Pentacyclic triterpenes modulate farnesoid X receptor expression in colonic epithelial cells: Implications for colonic secretory function

Autor: Fallon, Ciara M., Smyth, Jessica S., Quach, Andrew, Lajczak-McGinley, Natalia, O’Toole, Aoibhlinn, Barrett, Kim E., Sheridan, Helen, Keely, Stephen J.

Publikováno v: In Journal of Biological Chemistry November 2022 298(11)

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A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling.

Autor: Ní Cheallaigh C; Department of Clinical Medicine, Institute of Molecular Medicine, Trinity College Dublin and St. James's Hospital, D08 W9RT, Dublin, Ireland; Adjuvant Research Group, School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, D02 PN40, Dublin, Ireland. Electronic address: nicheacm@tcd.ie., Sheedy FJ; Department of Clinical Medicine, Institute of Molecular Medicine, Trinity College Dublin and St. James's Hospital, D08 W9RT, Dublin, Ireland., Harris J; Centre for Inflammatory Diseases, Southern Clinical School, Monash University Faculty of Medicine, Nursing and Health Sciences, Clayton, Victoria 3168, Australia., Muñoz-Wolf N; Adjuvant Research Group, School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, D02 PN40, Dublin, Ireland., Lee J; Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA., West K; Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA., McDermott EP; Inflammation Research Group, School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, D02 PN40, Dublin, Ireland., Smyth A; UCD Schools of Veterinary Medicine, Medicine and Medical Science, and Biomolecular and Biomedical Science, and UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland., Gleeson LE; Department of Clinical Medicine, Institute of Molecular Medicine, Trinity College Dublin and St. James's Hospital, D08 W9RT, Dublin, Ireland., Coleman M; Department of Clinical Medicine, Institute of Molecular Medicine, Trinity College Dublin and St. James's Hospital, D08 W9RT, Dublin, Ireland., Martinez N; Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA., Hearnden CH; Adjuvant Research Group, School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, D02 PN40, Dublin, Ireland., Tynan GA; Adjuvant Research Group, School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, D02 PN40, Dublin, Ireland., Carroll EC; Adjuvant Research Group, School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, D02 PN40, Dublin, Ireland., Jones SA; Centre for Inflammatory Diseases, Southern Clinical School, Monash University Faculty of Medicine, Nursing and Health Sciences, Clayton, Victoria 3168, Australia., Corr SC; Inflammation Research Group, School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, D02 PN40, Dublin, Ireland., Bernard NJ; Inflammation Research Group, School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, D02 PN40, Dublin, Ireland., Hughes MM; Inflammation Research Group, School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, D02 PN40, Dublin, Ireland., Corcoran SE; Inflammation Research Group, School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, D02 PN40, Dublin, Ireland., O'Sullivan M; Department of Clinical Medicine, Institute of Molecular Medicine, Trinity College Dublin and St. James's Hospital, D08 W9RT, Dublin, Ireland., Fallon CM; Department of Clinical Medicine, Institute of Molecular Medicine, Trinity College Dublin and St. James's Hospital, D08 W9RT, Dublin, Ireland., Kornfeld H; Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA., Golenbock D; Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA., Gordon SV; UCD Schools of Veterinary Medicine, Medicine and Medical Science, and Biomolecular and Biomedical Science, and UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland., O'Neill LA; Inflammation Research Group, School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, D02 PN40, Dublin, Ireland., Lavelle EC; Adjuvant Research Group, School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, D02 PN40, Dublin, Ireland; Advanced Materials and BioEngineering Research (AMBER), Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN), Trinity College, D02 PN40, Dublin, Ireland. Electronic address: lavellee@tcd.ie., Keane J; Department of Clinical Medicine, Institute of Molecular Medicine, Trinity College Dublin and St. James's Hospital, D08 W9RT, Dublin, Ireland.

Publikováno v: Immunity [Immunity] 2016 Feb 16; Vol. 44 (2), pp. 368-79.