Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Falko Partosch"'
Autor:
Monika Batke, Martin Gütlein, Falko Partosch, Ursula Gundert-Remy, Christoph Helma, Stefan Kramer, Andreas Maunz, Madeleine Seeland, Annette Bitsch
Publikováno v:
Frontiers in Pharmacology, Vol 7 (2016)
1.AbstractInterest is increasing in the development of non-animal methods for toxicological evaluations. These methods are however, particularly challenging for complex toxicological endpoints such as repeated dose toxicity. European Legislation, e.g
Externí odkaz:
https://doaj.org/article/0e0db98bc3f84328a4051111cc5ed665
Autor:
Oliver Licht, Franziska Breuer, Alina Baskirov, Katharina Blümlein, Rupert Kellner, Dirk Pallapies, Falko Partosch, Bianca Pieczyk, Susanne Schwonbeck, Petra Wiedemeier, Ariane Zwintscher
Publikováno v:
EFSA Supporting Publications. 19
An Extensive Literature Search (ELS) to collect and identify all studies published since 2009 and relevant to the topic organic arsenic in combination with the substance group characterisation, occurrence in food and toxicity was performed in the thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::415b980ac5fe88d8094166ddf2d1a379
https://doi.org/10.2903/sp.efsa.2022.en-7565
https://doi.org/10.2903/sp.efsa.2022.en-7565
Publikováno v:
Zahnmedizin up2date. 13:299-317
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e774bba88f5aac3c6aafd7e412a4eecc
https://doi.org/10.1055/a-0977-7856
https://doi.org/10.1055/a-0977-7856
Autor:
Falko Partosch, Claudia Röhl, Ursula Gundert-Remy, Klaus-Michael Wollin, Aswin Mangerich, Jan G. Hengstler, Alexius Freyberger, Thomas Gebel, Georg Damm, Heidi Foth, Thomas Schupp
Publikováno v:
Archives of Toxicology
Archives of toxicology, 94:2319-2329
Archives of toxicology, 94:2319-2329
Lead (Pb) exposure of consumers and the environment has been reduced over the past decades. Despite all measures taken, immission of Pb onto agricultural soils still occurs, with fertilizer application, lead shot from hunting activities, and Pb from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::842c7be410e1b747fe00b19b33652091
Autor:
Klaus-Michael Wollin, Heidi Foth, Claudia Röhl, Falko Partosch, Aswin Mangerich, Jan G. Hengstler, Thomas Gebel, Thomas Schupp, Alexius Freyberger, Ursula Gundert-Remy, Georg Damm
Publikováno v:
Archives of toxicology, 94:967-1016
Archives of Toxicology
Archives of Toxicology
The use of hydraulic fracturing (HF) to extract oil and natural gas has increased, along with intensive discussions on the associated risks to human health. Three technical processes should be differentiated when evaluating human health risks, namely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bd63cb3e084eb50ccc2b8ea07adc8aa
https://repository.publisso.de/resource/frl:6422814
https://repository.publisso.de/resource/frl:6422814
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 123:213-220
Mycobacterial diseases remain a significant cause of morbidity and mortality worldwide. Rifampicin and ethambutol are among the drugs recommended by WHO as first-line treatment. In this work, we addressed the question whether doses of the two anti-tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae83272bbbeb95f3180d0ad7821b1f7
https://doi.org/10.1111/bcpt.12995
https://doi.org/10.1111/bcpt.12995
Autor:
Ursula Gundert-Remy, Falko Partosch, Linda Reilly, José Cortiñas Abrahantes, Jean Lou Cm Dorne, George E.N. Kass, Rositsa Serafimova
Publikováno v:
Toxicology letters. 314
The Threshold of Toxicological Concern (TTC) concept integrates data on exposure, chemical structure, toxicity and metabolism to identify a safe exposure threshold value for chemicals with insufficient toxicity data for risk assessment. The TTC value
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::918354164320cb9b9697c5770c9aa4b3
https://pubmed.ncbi.nlm.nih.gov/31325634
https://pubmed.ncbi.nlm.nih.gov/31325634
Autor:
Falko Partosch, E. Di Consiglio, Emanuela Testai, Hans Mielke, Ursula Gundert-Remy, Reinhold Kreutz
Publikováno v:
Archives of Toxicology. 91:1663-1670
A physiologically based human kinetic model (PBHKM) was used to predict the in vivo ibuprofen dose leading to the same concentration-time profile as measured in cultured human hepatic cells (Truisi et al. in Toxicol Lett 233(2):172-186, 2015). We par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51b97878fdc22ca4f8de17d10366629f
https://doi.org/10.1007/s00204-016-1863-z
https://doi.org/10.1007/s00204-016-1863-z
Autor:
Hans Mielke, Falko Partosch, Ralf Stahlmann, Ursula Gundert-Remy, Susan Barlow, Burkhard Kleuser
Publikováno v:
Archives of Toxicology. 89:941-948
The TTC concept uses toxicological data from animal testing to derive generic human exposure threshold values (TTC values), below which the risk of adverse effects on human health is considered to be low. It uses distributions of no-observed-adverse-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69d8d57d3d9841ba73332efe57aa2fcf
https://doi.org/10.1007/s00204-014-1287-6
https://doi.org/10.1007/s00204-014-1287-6
Autor:
Christoph Helma, Monika Batke, Stefan Kramer, Falko Partosch, Madeleine Seeland, Martin Gütlein, Annette Bitsch, Andreas Maunz, Ursula Gundert-Remy
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 7 (2016)
Frontiers in Pharmacology, Vol 7 (2016)
Interest is increasing in the development of non-animal methods for toxicological evaluations. These methods are however, particularly challenging for complex toxicological endpoints such as repeated dose toxicity. European Legislation, e.g., the Eur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3737a446c05cee89f729a6d7f02d77be
https://pubmed.ncbi.nlm.nih.gov/27708580
https://pubmed.ncbi.nlm.nih.gov/27708580