Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Falko G. Falkner"'
Autor:
Johannes Lengler, Sogue Coulibaly, Bernadette Gruber, Reinhard Ilk, Josef Mayrhofer, Friedrich Scheiflinger, Werner Hoellriegl, Falko G. Falkner, Hanspeter Rottensteiner
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 581-588 (2020)
Gene therapy product release requires reliable and consistent demonstration of biopotency. In hemophilia B vectors, this is usually determined in vivo by measuring the plasma levels of the expressed human factor IX (FIX) transgene product in FIX knoc
Externí odkaz:
https://doaj.org/article/385fb00f577f4457ac3b71706cbf6f70
Autor:
Sogue Coulibaly, Friedrich Scheiflinger, Josef Mayrhofer, Hanspeter Rottensteiner, Reinhard Ilk, Werner Hoellriegl, Bernadette Gruber, Falko G. Falkner, Johannes Lengler
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss, Pp 581-588 (2020)
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss, Pp 581-588 (2020)
Gene therapy product release requires reliable and consistent demonstration of biopotency. In hemophilia B vectors, this is usually determined in vivo by measuring the plasma levels of the expressed human factor IX (FIX) transgene product in FIX knoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb849e8599c86f72ce720421abe2e77
http://europepmc.org/articles/PMC7139127
http://europepmc.org/articles/PMC7139127
Autor:
Otfried Kistner, Brian A Crowe, Walter Wodal, Astrid Kerschbaum, Helga Savidis-Dacho, Nicolas Sabarth, Falko G Falkner, Ines Mayerhofer, Wolfgang Mundt, Manfred Reiter, Leopold Grillberger, Christa Tauer, Michael Graninger, Alois Sachslehner, Michael Schwendinger, Peter Brühl, Thomas R Kreil, Hartmut J Ehrlich, P Noel Barrett
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9349 (2010)
The recent emergence and rapid spread of a novel swine-derived H1N1 influenza virus has resulted in the first influenza pandemic of this century. Monovalent vaccines have undergone preclinical and clinical development prior to initiation of mass immu
Externí odkaz:
https://doaj.org/article/371cf088181640879869f94a514c85ae
Autor:
Annett Hessel, Michael Schwendinger, Daniela Fritz, Sogue Coulibaly, Georg W Holzer, Nicolas Sabarth, Otfried Kistner, Walter Wodal, Astrid Kerschbaum, Helga Savidis-Dacho, Brian A Crowe, Thomas R Kreil, P Noel Barrett, Falko G Falkner
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12217 (2010)
BACKGROUND: The development of novel influenza vaccines inducing a broad immune response is an important objective. The aim of this study was to evaluate live vaccines which induce both strong humoral and cell-mediated immune responses against the no
Externí odkaz:
https://doaj.org/article/2b24e378b3064e2aa532a5ed5adbfba7
Autor:
Astrid Kerschbaum, Claudia Gaiswinkler, Thomas R. Kreil, Walter Wodal, M. Keith Howard, Falko G. Falkner, Daniel Portsmouth, Helga Savidis-Dacho, Richard Fritz, Sogue Coulibaly, Otfried Kistner, Stefan Kiermayr, Christina Piskernik, P. Noel Barrett, Christine Hohenadl
Publikováno v:
Vaccine. 30:4625-4631
Background Influenza viruses of subtype A/H9N2 are enzootic in poultry across Asia and the Middle East and are considered to have pandemic potential. The development of new vaccine manufacturing technologies is a cornerstone of influenza pandemic pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63d7875247d261b8104f653fa41580d7
https://doi.org/10.1016/j.vaccine.2012.04.102
https://doi.org/10.1016/j.vaccine.2012.04.102
Autor:
Alexandra Loew-Baselli, Hartmut J. Ehrlich, Klaus Orlinger, Eva-Maria Poellabauer, Richard Fritz, P. Noel Barrett, Thomas R. Kreil, Bernd Unger, Yvonne Hofmeister, Georg Holzer, Falko G. Falkner
Publikováno v:
The Journal of Infectious Diseases. 203:1556-1564
After vaccination of humans with tick-borne encephalitis virus (TBEV) vaccine, the extent of cross-neutralization between viruses of the European, Far Eastern, and Siberian subtypes of TBEV and Omsk hemorrhagic fever virus (OHFV) was analyzed. Hybrid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7e4101287a308b32cfc52969eda7ebe
https://doi.org/10.1093/infdis/jir122
https://doi.org/10.1093/infdis/jir122
Autor:
John Aaskov, Otfried Kistner, Helga Savidis-Dacho, Thomas R. Kreil, Susanne Brunner, P. Noel Barrett, Gerald Aichinger, Josef Mayrhofer, Hartmut J. Ehrlich, Karl Schmid, Georg Holzer, Falko G. Falkner, Sogue Coulibaly
Publikováno v:
Vaccine. 29:4132-4141
Ross River Virus has caused reported outbreaks of epidemic polyarthritis, a chronic debilitating disease associated with significant long-term morbidity in Australia and the Pacific region since the 1920s. To address this public health concern, a for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e5032940f99084ba11c1bb3c9abf1ed
https://doi.org/10.1016/j.vaccine.2011.03.089
https://doi.org/10.1016/j.vaccine.2011.03.089
Autor:
Burtram C. Fielding, Seng Gee Lim, Kuo-Ming Lip, Josef Mayrhofer, Shuo Shen, Falko G. Falkner, Hsueh-Ling Janice Oh, Zhi-Hong Li, Xiaoming Yang, Yee-Joo Tan, Le-Ann Hwang, Jianlin Fu, Chih-Fong Chou, Choong-Tat Keng, Wanjin Hong, Timothy H.P. Tan, Aihua Zhang
Publikováno v:
Journal of Virology
We have previously shown that an Escherichia coli -expressed, denatured spike (S) protein fragment of the severe acute respiratory coronavirus, containing residues 1029 to 1192 which include the heptad repeat 2 (HR2) domain, was able to induce neutra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d86e7cc7df805454799b1d57eb9f9a53
Publikováno v:
Virology. 337:235-241
The Escherichia coli thymidine kinase/thymidylate kinase (tk/tmk) fusion gene encodes an enzyme that efficiently converts the prodrug 3′-azido-2′,3′-dideoxythymidine (AZT) into its toxic triphosphate derivative, a substance which stops DNA chai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f965fcbf88543fc5075bd1e60e36dea9
https://doi.org/10.1016/j.virol.2005.04.009
https://doi.org/10.1016/j.virol.2005.04.009
Autor:
Marijan Gerencer, V. Wieser, M. Schmidt, B. T. Ober, Werner Gritschenberger, Sogue Coulibaly, Falko G. Falkner, Helga Savidis-Dacho, Peter Brühl
Publikováno v:
Journal of Virology. 76:7713-7723
Potent and safe vaccinia virus vectors inducing cell-mediated immunity are needed for clinical use. Replicating vaccinia viruses generally induce strong cell-mediated immunity; however, they may have severe adverse effects. As a vector for clinical u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baeaa3b7b7b973eeeb71189fd7b5fafd
https://doi.org/10.1128/jvi.76.15.7713-7723.2002
https://doi.org/10.1128/jvi.76.15.7713-7723.2002