Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Falko Apel"'
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0282919 (2023)
Granulomatosis with Polyangiitis (GPA) is a small vessel vasculitis typically associated with release of neutrophil extracellular traps (NETs) by activated neutrophils. In this study, we further aimed to investigate the contributions of neutrophils a
Externí odkaz:
https://doaj.org/article/446ea32caccf4f1ba4bee56b2683ed8b
Autor:
Gabriel Sollberger, Robert Streeck, Falko Apel, Brian Edward Caffrey, Arthur I Skoultchi, Arturo Zychlinsky
Publikováno v:
eLife, Vol 9 (2020)
Neutrophils are important innate immune cells that tackle invading pathogens with different effector mechanisms. They acquire this antimicrobial potential during their maturation in the bone marrow, where they differentiate from hematopoietic stem ce
Externí odkaz:
https://doaj.org/article/756d71219e59472cafbb39ce56bdad90
Autor:
Karl-Peter Hopfner, Robert Streeck, Christian Karl Frese, Arturo Zychlinsky, Falko Apel, Lorenz Sebastian Knackstedt, Liudmila Andreeva, Christian Goosmann
Publikováno v:
Science Signaling. 14
Neutrophil extracellular traps (NETs) are structures consisting of chromatin and antimicrobial molecules that are released by neutrophils during a form of regulated cell death called NETosis. NETs trap invading pathogens, promote coagulation, and act
Autor:
Brian E. Caffrey, Falko Apel, Robert Streeck, Arthur I. Skoultchi, Gabriel Sollberger, Arturo Zychlinsky
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Neutrophils are important innate immune cells that tackle invading pathogens with different effector mechanisms. They acquire this antimicrobial potential during their maturation in the bone marrow, where they differentiate from hematopoietic stem ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba8246a54ed234f174838ae6653500d
https://hdl.handle.net/21.11116/0000-0006-8A94-721.11116/0000-0006-8A96-5
https://hdl.handle.net/21.11116/0000-0006-8A94-721.11116/0000-0006-8A96-5
Autor:
Evelin Schwarzer, Bärbel Raupach, Jean Langhorne, Valentina Barrera, Sebastian Lorenz Knackstedt, Simon P. Harding, Christopher A. Moxon, Deirdre Cunningham, Sam Patel, Renate Krüger, Aase Berg, Volker Brinkmann, Falko Apel, Kari Otterdal, Borko Amulic, Benjamin Mordmüller, Athina Georgiadou, Aubrey J. Cunnington, Ulrike Abu-Abed, Arturo Zychlinsky
Publikováno v:
Knackstedt, S L, Georgiadou, A, Apel, F, Abu-Abed, U, Moxon, C A, Cunnington, A J, Raupach, B, Cunningham, D, Langhorne, J, Krüger, R, Barrera, V, Harding, S P, Berg, A, Patel, S, Otterdal, K, Mordmüller, B, Schwarzer, E, Brinkmann, V, Zychlinsky, A & Amulic, B 2019, ' Neutrophil extracellular traps drive inflammatory pathogenesis in malaria ', Science Immunology, vol. 4, no. 40, eaaw0336 . https://doi.org/10.1126/sciimmunol.aaw0336
SCIENCE IMMUNOLOGY
Science Immunology
SCIENCE IMMUNOLOGY
Science Immunology
Neutrophils are essential innate immune cells that extrude chromatin in the form of neutrophil extracellular traps (NETs) when they die. This form of cell death has potent immunostimulatory activity. We show that heme-induced NETs are essential for m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8690c8d7c84f48f18692ecb1587269
https://research-information.bris.ac.uk/ws/files/214087360/all_revisions_no_track_changes_03062019_SUBMITTED.pdf
https://research-information.bris.ac.uk/ws/files/214087360/all_revisions_no_track_changes_03062019_SUBMITTED.pdf
Autor:
Slava Stamova, Malte von Bonin, Anja Feldmann, Marc Schmitz, Holger Bartsch, Martin Bornhäuser, Rebekka Wehner, Falko Apel, Claudia Arndt, Marc Cartellieri, Michael Bachmann, Gerhard Ehninger, Stefanie Koristka
Publikováno v:
Analytical biochemistry. 423(2)
There is growing interest in the development of novel single-chain bispecific antibodies for retargeting of immune effector T cells to tumor cells. Until today, functional fusion constructs consisting of a single-chain bispecific antibody and a fluor