Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Falk, Weih"'
Autor:
Laura B. Kuhn, Stefanie Valentin, Kristina Stojanovic, Daniel C. Strobl, Tea Babushku, Yan Wang, Ursula Rambold, Laura Scheffler, Sonja Grath, Dorothy John-Robbert, Helmut Blum, Annette Feuchtinger, Andreas Blutke, Falk Weih, Daisuke Kitamura, Roland Rad, Lothar J. Strobl, Ursula Zimber-Strobl
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Activation of CD40-signaling contributes to the initiation, progression and drug resistance of B cell lymphomas. We contributed to this knowledge by showing that constitutive CD40-signaling in B cells induces B cell hyperplasia and finally B cell lym
Externí odkaz:
https://doaj.org/article/54c53ebf14244ecf932108fe1c3c9659
Autor:
Zekiye Buket Yılmaz, Bente Kofahl, Patrick Beaudette, Katharina Baum, Inbal Ipenberg, Falk Weih, Jana Wolf, Gunnar Dittmar, Claus Scheidereit
Publikováno v:
Cell Reports, Vol 9, Iss 5, Pp 1756-1769 (2014)
Summary: The mechanisms that govern proteolytic maturation or complete destruction of the precursor proteins p100 and p105 are fundamental to homeostasis and activation of NF-κB; however, they remain poorly understood. Using mass-spectrometry-based
Externí odkaz:
https://doaj.org/article/ca93ccf850fe44099c3c3ee7a2b39c83
Autor:
Anja Döhler, Theresa Schneider, Ina Eckert, Eliana Ribechini, Nico Andreas, Marc Riemann, Boris Reizis, Falk Weih, Manfred B. Lutz
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Thymus-derived natural Foxp3+ CD4+ regulatory T cells (nTregs) play a key role in maintaining immune tolerance and preventing autoimmune disease. Several studies indicate that dendritic cells (DCs) are critically involved in the maintenance and proli
Externí odkaz:
https://doaj.org/article/2a667aeec8c04584bd5bd1e52dbb1a7c
Autor:
Anna-Lena Geiselhöringer, Caspar Ohnmacht, Marc Riemann, Maria Potthast, Falk Weih, Garima Garg, Julia Riewaldt, Karsten Kretschmer, Carsten B. Schmidt-Weber, Renske J. de Jong, Nico Andreas, Thomas Korn, Jean-Philippe Girard, Simon Blank, Dennis Russkamp
Publikováno v:
J. Immunol. 203, 2602-2613 (2019)
The Journal of Immunology
The Journal of Immunology
Foxp3+ regulatory T cells are well-known immune suppressor cells in various settings. In this study, we provide evidence that knockout of the relB gene in dendritic cells (DCs) of C57BL/6 mice results in a spontaneous and systemic accumulation of Fox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dee9b43798aebfb65c5472c803c1f7f9
https://doi.org/10.4049/jimmunol.1801530
https://doi.org/10.4049/jimmunol.1801530
Autor:
Nico Andreas, Andreas Thuy, Sravya Sreekantapuram, Ronny Haenold, Falk Weih, Ievgen O. Koliesnik
Publikováno v:
Immunobiology. 224:687-696
Abstarct Regulatory T cells (Tregs) maintain immune homeostasis and play an important role in tissue regeneration after injury. Mutations affecting development or homeostasis of Tregs lead to immune pathologies in humans and are often fatal in mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e4fc8d0220c582c6f833b463efb577b
https://doi.org/10.1016/j.imbio.2019.06.001
https://doi.org/10.1016/j.imbio.2019.06.001
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42741 (2012)
BackgroundConstitutive activation of the alternative NF-κB pathway leads to marginal zone B cell expansion and disorganized spleen microarchitecture. Furthermore, uncontrolled alternative NF-κB signaling may result in the development and progressio
Externí odkaz:
https://doaj.org/article/d13c4b0f40de4791ba85cb451391c701
Autor:
Mariem Ben-Abdallah, Aude Sturny-Leclère, Patrick Avé, Anne Louise, Frédérique Moyrand, Falk Weih, Guilhem Janbon, Sylvie Mémet
Publikováno v:
PLoS Pathogens, Vol 8, Iss 3, p e1002555 (2012)
Microbial pathogens have developed efficient strategies to compromise host immune responses. Cryptococcus neoformans is a facultative intracellular pathogen, recognised as the most common cause of systemic fungal infections leading to severe meningoe
Externí odkaz:
https://doaj.org/article/2e0bf8ce968944979850595b9c88ee25
Autor:
Tim Sparwasser, Carla N. Castro, Christian Engelmann, Nico Andreas, Thomas Kamradt, Marco Groth, Ronny Haenold, Marc Riemann, Ievgen O. Koliesnik, Falk Weih
Publikováno v:
European Journal of Immunology. 48:923-936
The NF-κB transcription factor subunit RelB is important for the full activation of conventional dendritic cells (cDCs) during T-cell-dependent immune responses. Although the number of splenic DCs is greatly reduced in RelBnull mice, the cause and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86330029632f2b3a18d92ad0db2a9d6a
https://doi.org/10.1002/eji.201747332
https://doi.org/10.1002/eji.201747332
Autor:
Sravya Sreekantapuram, Ievgen O. Koliesnik, Nico Andreas, Vasily S. Romanov, Ronny Haenold, Branislav Krljanac, Falk Weih
Publikováno v:
Immunobiology. 223:191-199
The role of the alternative NF-κB pathway is mainly attributed to the lymphoid organ formation and blood cancer. However, its involvement in lymphocyte differentiation is not clearly defined. Recently, we have shown that uncontrolled activation of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::447f462466e91984d5764d7f459d46ae
https://doi.org/10.1016/j.imbio.2017.10.026
https://doi.org/10.1016/j.imbio.2017.10.026
Autor:
Nuno R dos Santos, Maryvonne Williame, Stéphanie Gachet, Françoise Cormier, Anne Janin, Debra Weih, Falk Weih, Jacques Ghysdael
Publikováno v:
PLoS ONE, Vol 3, Iss 7, p e2555 (2008)
BACKGROUND: The Rel/NF-kappaB transcription factors are often activated in solid or hematological malignancies. In most cases, NF-kappaB activation is found in malignant cells and results from activation of the canonical NF-kappaB pathway, leading to
Externí odkaz:
https://doaj.org/article/93370d6cf1e54611a04af7bff76c713b