Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Falk, Butter"'
Autor:
Henriette Franz, Maitreyi Rathod, Aude Zimmermann, Chiara Stüdle, Vivien Beyersdorfer, Karen Leal-Fischer, Pauline Hanns, Tomás Cunha, Dario Didona, Michael Hertl, Marion Scheibe, Falk Butter, Enno Schmidt, Volker Spindler
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Cell-cell junctions, and specifically desmosomes, are crucial for robust intercellular adhesion. Desmosomal function is compromised in the autoimmune blistering skin disease pemphigus vulgaris. We combine whole-genome knockout screening and
Externí odkaz:
https://doaj.org/article/5299e4b0ab3a4e0d82122e76ecb37ed4
Autor:
Marlene Reichel, Olga Schmidt, Mandy Rettel, Frank Stein, Tino Köster, Falk Butter, Dorothee Staiger
Publikováno v:
BMC Plant Biology, Vol 24, Iss 1, Pp 1-21 (2024)
Abstract Background The interaction of proteins with RNA in the cell is crucial to orchestrate all steps of RNA processing. RNA interactome capture (RIC) techniques have been implemented to catalogue RNA- binding proteins in the cell. In RIC, RNA-pro
Externí odkaz:
https://doaj.org/article/9427ac8f646348919b24242a139042b5
Autor:
Alexandra Nguyen, Al-Hassan M. Mustafa, Alessa K. Leydecker, Melisa Halilovic, Janine Murr, Falk Butter, Oliver H. Krämer
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract As a major source of cellular serine and threonine phosphatase activity, protein phosphatase-2A (PP2A) modulates signaling pathways in health and disease. PP2A complexes consist of catalytic, scaffolding, and B-type subunits. Seventeen PP2A
Externí odkaz:
https://doaj.org/article/9e6174433b8147c5a564a52252e4791f
Autor:
Christoph Hieber, Al-Hassan M. Mustafa, Sarah Neuroth, Sven Henninger, Hans-Peter Wollscheid, Joanna Zabkiewicz, Michelle Lazenby, Caroline Alvares, Siavosh Mahboobi, Falk Butter, Walburgis Brenner, Matthias Bros, Oliver H. Krämer
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 117076- (2024)
Hyperactive FMS-like receptor tyrosine kinase-3 mutants with internal tandem duplications (FLT3-ITD) are frequent driver mutations of aggressive acute myeloid leukemia (AML). Inhibitors of FLT3 produce promising results in rationally designed cotreat
Externí odkaz:
https://doaj.org/article/92a388417b2242c48063d7ece8629a1e
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110250- (2024)
Summary: Precise double-strand break (DSB) repair is a paramount for genome stability. Homologous recombination (HR) repairs DSBs when cyclin-dependent kinase (CDK) activity is high, which correlates with the availability of the sister chromatid as a
Externí odkaz:
https://doaj.org/article/caa75a24e2ff430db9602a22bb5853b5
Autor:
Hanna Braun, Ziyan Xu, Fiona Chang, Nikenza Viceconte, Grishma Rane, Michal Levin, Liudmyla Lototska, Franziska Roth, Alexia Hillairet, Albert Fradera-Sola, Vartika Khanchandani, Zi Wayne Sin, Wai Khang Yong, Oliver Dreesen, Yang Yang, Yunyu Shi, Fudong Li, Falk Butter, Dennis Kappei
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Telomeres are nucleoprotein structures at the ends of linear chromosomes. In humans, they consist of TTAGGG repeats, which are bound by dedicated proteins such as the shelterin complex. This complex blocks unwanted DNA damage repair at telom
Externí odkaz:
https://doaj.org/article/910ba664c7cf434ba6e5cf34d3a5ba0f
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-14 (2023)
Abstract Human cytomegalovirus (HCMV) is a pathogen of high medical relevance. Subviral Dense Bodies (DB) were developed as a vaccine candidate to ameliorate the severe consequences of HCMV infection. Development of such a candidate vaccine for human
Externí odkaz:
https://doaj.org/article/6bc4e020e29c48c8b2e13f87445089ac
Autor:
Gergana Taleva, Michaela Husová, Brian Panicucci, Carolina Hierro-Yap, Erika Pineda, Marc Biran, Martin Moos, Petr Šimek, Falk Butter, Frédéric Bringaud, Alena Zíková
Publikováno v:
PLoS Pathogens, Vol 19, Iss 10, p e1011699 (2023)
The long slender bloodstream form Trypanosoma brucei maintains its essential mitochondrial membrane potential (ΔΨm) through the proton-pumping activity of the FoF1-ATP synthase operating in the reverse mode. The ATP that drives this hydrolytic reac
Externí odkaz:
https://doaj.org/article/4dc3c4c623334b23bad5e9817194ed8a
Autor:
Annika Schmidt, Hui Zhang, Stephanie Schmitt, Cathia Rausch, Oliver Popp, Jiaxuan Chen, Dusan Cmarko, Falk Butter, Gunnar Dittmar, Frederik Lermyte, M. Cristina Cardoso
Publikováno v:
Cells, Vol 13, Iss 2, p 139 (2024)
Pericentric heterochromatin (PCH) forms spatio-temporarily distinct compartments and affects chromosome organization and stability. Albeit some of its components are known, an elucidation of its proteome and how it differs between tissues in vivo is
Externí odkaz:
https://doaj.org/article/935718bd7cc64150bf5f44bb4ff1a758
Autor:
Sandra Trindade, Mariana De Niz, Mariana Costa-Sequeira, Tiago Bizarra-Rebelo, Fábio Bento, Mario Dejung, Marta Valido Narciso, Lara López-Escobar, João Ferreira, Falk Butter, Frédéric Bringaud, Erida Gjini, Luisa M. Figueiredo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Trypanosoma brucei parasites invade different organs, such as the central nervous system, adipose tissue, and skin in mammalian host. Here, Trindade et al. perform mathematical modelling to show that adipose tissue forms (ATFs) grow slower than the b
Externí odkaz:
https://doaj.org/article/c718bb6bea3442f3958b2d73377049be