Inflammatory breast cancer microenvironment repertoire based on DNA methylation data deconvolution reveals actionable targets to enhance the treatment efficacy.

Autor: Calanca N; Department of Clinical Genetics, University Hospital of Southern Denmark, Beriderbakken 4, Vejle, DK, 7100, Denmark.; Department of Chemical and Biological Sciences, Institute of Biosciences, São Paulo State University (UNESP), Botucatu, SP, 18618-689, Brazil., Faldoni FLC; Department of Clinical Genetics, University Hospital of Southern Denmark, Beriderbakken 4, Vejle, DK, 7100, Denmark., Souza CP; Medical Oncology Department, Barretos Cancer Hospital, Pio XII Foundation, Barretos, SP, 14784-400, Brazil., Souza JS; Health Technology Institute, SENAI CIMATEC, Salvador, BA, 41650-010, Brazil., de Souza Alves BE; Department of Physiology and Pharmacology, Drug Research and Development Center (NPDM), Faculty of Medicine, Federal University of Ceará, Fortaleza, 60430-270, Brazil., Soares MBP; Health Technology Institute, SENAI CIMATEC, Salvador, BA, 41650-010, Brazil.; Gonçalo Moniz Institute, FIOCRUZ, Salvador, BA, 40296-710, Brazil., Wong DVT; Department of Physiology and Pharmacology, Drug Research and Development Center (NPDM), Faculty of Medicine, Federal University of Ceará, Fortaleza, 60430-270, Brazil., Lima-Junior RCP; Department of Physiology and Pharmacology, Drug Research and Development Center (NPDM), Faculty of Medicine, Federal University of Ceará, Fortaleza, 60430-270, Brazil., Marchi FA; Department of Head and Neck Surgery, University of São Paulo Medical School, São Paulo, SP, 05402-000, Brazil.; Center for Translational Research in Oncology, Cancer Institute of the State of São Paulo (ICESP), São Paulo, SP, 01246-000, Brazil., Rainho CA; Department of Chemical and Biological Sciences, Institute of Biosciences, São Paulo State University (UNESP), Botucatu, SP, 18618-689, Brazil., Rogatto SR; Department of Clinical Genetics, University Hospital of Southern Denmark, Beriderbakken 4, Vejle, DK, 7100, Denmark. silvia.rogatto@unesp.br.; Institute of Regional Health Research, University of Southern Denmark, Odense, 5000, Denmark. silvia.rogatto@unesp.br.; Botucatu Medical School Hospital, São Paulo State University (UNESP), Botucatu, SP, Brazil. silvia.rogatto@unesp.br.

Publikováno v: Journal of translational medicine [J Transl Med] 2024 Aug 05; Vol. 22 (1), pp. 735. Date of Electronic Publication: 2024 Aug 05.

Inflammatory Breast Cancer: Clinical Implications of Genomic Alterations and Mutational Profiling.

Autor: Faldoni FLC; International Research Center, A.C.Camargo Cancer Center, São Paulo 01508-010, Brazil.; Department of Clinical Genetics, University Hospital of Southern Denmark, 7100 Vejle, Denmark., Villacis RAR; Department of Genetics and Morphology, Institute of Biological Sciences, University of Brasília-UnB, Brasília 70910-900, Brazil., Canto LM; Department of Clinical Genetics, University Hospital of Southern Denmark, 7100 Vejle, Denmark., Fonseca-Alves CE; Department of Veterinary Surgery and Anesthesiology, School of Veterinary Medicine and Animal Science, São Paulo State University-UNESP, Botucatu 18618-681, Brazil., Cury SS; Department of Structural and Functional Biology, Institute of Biosciences, São Paulo State University-UNESP, Botucatu 18618-689, Brazil., Larsen SJ; Department of Mathematics and Computer Science, University of Southern Denmark, 5230 Odense, Denmark., Aagaard MM; Department of Clinical Genetics, University Hospital of Southern Denmark, 7100 Vejle, Denmark., Souza CP; Department of Breast and Gynecologic Oncology, Barretos Cancer Hospital, Pio XII Foundation, Barretos 14784-390, Brazil., Scapulatempo-Neto C; Molecular Oncology Research Center, Barretos, SP, 14784-400, and Diagnósticos da América (DASA), Barueri 01525-001, Brazil., Osório CABT; Department of Pathology, A.C.Camargo Cancer Center, São Paulo 01525-001, Brazil., Baumbach J; Department of Mathematics and Computer Science, University of Southern Denmark, 5230 Odense, Denmark.; TUM School of Life Sciences Weihenstephan, Technical University of Munich, 85354 Freising, Germany., Marchi FA; International Research Center, A.C.Camargo Cancer Center, São Paulo 01508-010, Brazil., Rogatto SR; Department of Clinical Genetics, University Hospital of Southern Denmark, 7100 Vejle, Denmark.; Institute of Regional Health Research, University of Southern Denmark, 500 Odense, Denmark.

Publikováno v: Cancers [Cancers (Basel)] 2020 Sep 30; Vol. 12 (10). Date of Electronic Publication: 2020 Sep 30.