Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Falco Reissig"'
Publikováno v:
Pharmaceuticals, Vol 16, Iss 12, p 1720 (2023)
Background: The combination of platinum-containing cytostatic drugs with different radiation qualities has been studied for years. Despite their massive side effects, these drugs still belong to the therapeutic portfolio in cancer treatment. To overc
Externí odkaz:
https://doaj.org/article/5a8f05bb2a0d4c1d897a766a25194817
Autor:
Falco Reissig, Dr. Kristof Zarschler, Dr. René Hübner, Dr. Hans‐Jürgen Pietzsch, Prof. Dr. Klaus Kopka, Dr. Constantin Mamat
Publikováno v:
ChemistryOpen, Vol 9, Iss 8, Pp 797-805 (2020)
Abstract The treatment of cancer patients with α‐particle‐emitting therapeutics continues to gain in importance and relevance. The range of radiopharmaceutically relevant α‐emitters is limited to a few radionuclides, as stable chelators or ca
Externí odkaz:
https://doaj.org/article/438f32c0cb654ab9b3871122b6845a96
Autor:
Santiago Andrés Brühlmann, Martin Walther, Martin Kreller, Falco Reissig, Hans-Jürgen Pietzsch, Torsten Kniess, Klaus Kopka
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 314 (2023)
Theranostic matched pairs of radionuclides have aroused interest during the last couple of years, and in that sense, copper is one element that has a lot to offer, and although 61Cu and 64Cu are slowly being established as diagnostic radionuclides fo
Externí odkaz:
https://doaj.org/article/81e626fb223d4ae986ac978a77c95224
Autor:
Santiago Andrés Brühlmann, Martin Kreller, Hans-Jürgen Pietzsch, Klaus Kopka, Constantin Mamat, Martin Walther, Falco Reissig
Publikováno v:
Pharmaceuticals, Vol 15, Iss 10, p 1167 (2022)
Targeted Alpha Therapy is a research field of highest interest in specialized radionuclide therapy. Over the last decades, several alpha-emitting radionuclides have entered and left research topics towards their clinical translation. Especially, 225A
Externí odkaz:
https://doaj.org/article/e1bd40fef1c94cd9bfea8361bca86f00
Autor:
Falco Reissig, David Bauer, Martin Ullrich, Martin Kreller, Jens Pietzsch, Constantin Mamat, Klaus Kopka, Hans-Jürgen Pietzsch, Martin Walther
Publikováno v:
Pharmaceuticals, Vol 13, Iss 10, p 272 (2020)
Barium-131 is a single photon emission computed tomography (SPECT)-compatible radionuclide for nuclear medicine and a promising diagnostic match for radium-223/-224. Herein, we report on the sufficient production route 133Cs(p,3n)131Ba by using 27.5
Externí odkaz:
https://doaj.org/article/d47137eec1fc4101b331b6b8c56d1e9f
Autor:
Falco Reissig, Constantin Mamat, Joerg Steinbach, Hans-Juergen Pietzsch, Robert Freudenberg, Carlos Navarro-Retamal, Julio Caballero, Joerg Kotzerke, Gerd Wunderlich
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0161973 (2016)
It is evident that 99mTc causes radical-mediated DNA damage due to Auger electrons, which were emitted simultaneously with the known γ-emission of 99mTc. We have synthesized a series of new 99mTc-labeled pyrene derivatives with varied distances betw
Externí odkaz:
https://doaj.org/article/14586482c8e746e984cd5fa3cce06f2e
Publikováno v:
Nuclear Medicine and Biology 98(2021), 59-68
With the exception of beryllium, divalent cations of every alkaline earth metal are characterized by their calcimimetic behavior. Thus, in vivo biodistribution of these cations mostly occurs in form of a massive accumulation in bone tissues, consisti
Autor:
Constantin Mamat, Falco Reissig
Publikováno v:
ChemistryOpen 11(2022), e202200039
The increasing application of positron emission tomography (PET) in nuclear medicine has stimulated the extensive development of a multitude of novel and versatile techniques to introduce fluorine-18 especially for the radiolabelling of biologically
Autor:
Jörg Kotzerke, Roswitha Runge, Robert Freudenberg, Armin Lühr, Falco Reissig, Gerd Wunderlich
Publikováno v:
Nuclear Medicine and Biology. :65-70
Introduction Radiation-induced DNA damage occurs from direct and indirect effects. The induction is influenced by the physical characteristics of the radionuclide, especially its linear energy transfer. Hypoxia reduces the effect of irradiation treat
Autor:
Falco Reissig, Kristof Zarschler, Zbynek Novy, Milos Petrik, Katerina Bendova, Daniela Kurfurstova, Jan Bouchal, Marie-Charlotte Ludik, Florian Brandt, Klaus Kopka, Marta Khoylou, Hans-Jürgen Pietzsch, Marian Hajduch, Constantin Mamat
Publikováno v:
Theranostics 12(2022), 7203-7215
Rationale: Small 225Ac-labeled prostate-specific membrane antigen (PSMA)-targeted radioconjugates have been described for targeted alpha therapy of metastatic castration-resistant prostate cancer. Transient binding to serum albumin as a highly abunda
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c8b8c884205da5c842281f61ee28cb
https://www.hzdr.de/publications/Publ-34927-1
https://www.hzdr.de/publications/Publ-34927-1