Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Falco Kilchmann"'
Autor:
Sachin Kotak, Silvan D. Boss, Pierre Gönczy, Mahendra Awale, Jean-Louis Reymond, Maria J. Marcaida, Thomas Schick, Falco Kilchmann
Publikováno v:
Journal of medicinal chemistry
Here we report the discovery of a selective inhibitor of Aurora A, a key regulator of cell division and potential anticancer target. We used the atom category extended ligand overlap score (xLOS), a 3D ligand-based virtual screening method recently d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02b7e44e14199cb5fa7d72bf28e107f4
https://doi.org/10.1021/acs.jmedchem.6b00709
https://doi.org/10.1021/acs.jmedchem.6b00709
Autor:
Veronika Ehmke, Cornelia Heindl, Tanja Schirmeister, Falco Kilchmann, Jin Huang, François Diederich, Kunqiang Cui
Publikováno v:
MEDCHEMCOMM
Proteases of protozoan parasites have emerged as promising targets in drug design and discovery due to their indispensable roles in the life cycles of the parasites. For the development of new therapeutic agents against the malarial parasite Plasmodi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaa096edb5b39dea79ae86acc1f6169f
https://doi.org/10.1039/c1md00115a
https://doi.org/10.1039/c1md00115a