Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Fakhriedzwan Idris"'
Publikováno v:
Expert Opinion on Drug Discovery. 16:47-58
From both a public health and economic perspective, vaccination is arguably the most effective approach to combat endemic and pandemic infectious diseases. Dengue affects more than 100 countries in the tropical and subtropical world, with 100-400 mil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baa4e39f92bf3b9a9308a9aea678a3f8
https://doi.org/10.1080/17460441.2020.1811675
https://doi.org/10.1080/17460441.2020.1811675
Autor:
Edem, Gavor, Yeu Khai, Choong, Nikhil Kumar, Tulsian, Digant, Nayak, Fakhriedzwan, Idris, Hariharan, Sivaraman, Donald Heng Rong, Ting, Alonso, Sylvie, Yu Keung, Mok, R Manjunatha, Kini, J, Sivaraman
Publikováno v:
Life Science Alliance
Using high-resolution structure, we have characterized the substrate specificity of Aedes aegypti procarboxypeptidase B1 and provided mechanistic insights into the binding and inhibition of DENV
Metallocarboxypeptidases play critical roles in th
Metallocarboxypeptidases play critical roles in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::46c8150c1cb0a96cbc76714565d7851e
https://pubmed.ncbi.nlm.nih.gov/34750241
https://pubmed.ncbi.nlm.nih.gov/34750241
Publikováno v:
Archives of Virology. 164:1069-1083
The blood-brain barrier (BBB) is a physical barrier that restricts the passage of cells and molecules as well as pathogens into the central nervous system (CNS). Some viruses enter the CNS by disrupting the BBB, while others can reach the CNS without
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a2fb446de6db23a36b5f55bd47c4836
https://doi.org/10.1007/s00705-019-04175-3
https://doi.org/10.1007/s00705-019-04175-3
Autor:
Chanditha Hapuarachchi, Eunice Tze Xin Tan, Yukei Oo, Sylvie Alonso, Lee Ching Ng, Janice Zuo Hui Chia, Fakhriedzwan Idris, Clement Peng Hee Boey, Pei Xuan Lee, Li Ching Ong, Donald Heng Rong Ting, Yen Leong Chua
Publikováno v:
The Journal of Experimental Medicine
Lee et al. show that circulating NS1 protein does not contribute to dengue pathogenesis in mice infected with highly virulent DENV2 strains. Instead, structural prME region is found to play a critical role in the in vivo fitness and virulence of thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aab02235485ae2d146ecf214c817dc2c
http://europepmc.org/articles/PMC7478733
http://europepmc.org/articles/PMC7478733
Autor:
Donald Heng Rong Ting, Alonso Sylvie, Digant Nayak, Yu-Keung Mok, Fakhriedzwan Idris, Yeu Khai Choong, Edem Gavor, Nikhil Kumar Tulsian, Hariharan Sivaraman, R. Manjunatha Kini, J. Sivaraman
Publikováno v:
Life Science Alliance. 5:e202101211
Metallocarboxypeptidases play critical roles in the development of mosquitoes and influence pathogen/parasite infection of the mosquito midgut. Here, we report the crystal structure of Aedes aegypti procarboxypeptidase B1 (PCPBAe1), characterized its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0a479660352b79010ccc0d8bacd9ab0
https://doi.org/10.26508/lsa.202101211
https://doi.org/10.26508/lsa.202101211
Publikováno v:
Archives of Virology
Dengue virus, an RNA virus belonging to the genus Flavivirus, affects 50 million individuals annually, and approximately 500,000-1,000,000 of these infections lead to dengue hemorrhagic fever or dengue shock syndrome. With no licensed vaccine or spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e19fc78b553509d3cd973b1f553bb8f
https://doi.org/10.1007/s00705-016-2855-2
https://doi.org/10.1007/s00705-016-2855-2
Blood-brain barrier (BBB) is a selective barrier formed by the endothelial cells that line cerebral microvessels. It serves as a physical barrier due to the presence of complex tight junctions between adjacent endothelial cells which limits the parac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac272c0168abec1c9c9e699bac135aa1
IntroductionComplete inactivation of virus is crucial before samples are manipulated outside of biological containment areas or general cleaning. There are several control methods that could decrease the risk from viral contamination on surfaces, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5befd1dfd36a877b44076acfbea4203f
https://doi.org/10.1101/427666
https://doi.org/10.1101/427666
Publikováno v:
Journal of vector ecology : journal of the Society for Vector Ecology. 38(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df81339143c1a18d985391c356555890
https://pubmed.ncbi.nlm.nih.gov/23701628
https://pubmed.ncbi.nlm.nih.gov/23701628
Autor:
J. Lim, H. Muharram, Fakhriedzwan Idris, Uta Meyding-Lamadé, U. Khalsum, Nurul Adhwa Rahman, H. Abdul, Suwarni Diah, Eva Maria Craemer
Publikováno v:
Journal of the Neurological Sciences. 357:e4
Background: European tick-borne encephalitis (TBE) commonly presents with neurological disturbances, whereas primary psychiatric manifestations are rare. Aim: To report a case of acute TBE presenting as major depressive episode. Case report: A 72-yea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2e6751ed5ba58d9f650d914e101d523
https://doi.org/10.1016/j.jns.2015.08.094
https://doi.org/10.1016/j.jns.2015.08.094