Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Fakhraddin Naghibalhossaini"'
Publikováno v:
Pharmaceutical Sciences, Vol 30, Iss 1, Pp 116-128 (2024)
Background: Emerging evidence suggests that epigenetic mechanisms contribute to 5-fluorouracil (5-FU) resistance in colorectal cancer (CRC). However, there is limited research on the direct impact of 5-FU on epigenetic alterations in CRC. This study
Externí odkaz:
https://doaj.org/article/58e69ea437934e18a01236ab8140c07b
Autor:
Zahra Khoshdel, Naser Gholijani, Maryam Niknam, Nasim Rahmani, Mohsen Hemmati-Dinarvand, Fakhraddin Naghibalhossaini
Publikováno v:
Dermatology Practical & Conceptual, Vol 12, Iss 4 (2022)
Introduction: Vitiligo is a chronic skin disease, which its etiopathogenesis is not fully understood. Numerous studies have suggested that oxidative stress may play a role in the pathophysiology of vitiligo. There are controversial reports as to the
Externí odkaz:
https://doaj.org/article/30f9f9d5452a427f8e406f00d8e7bd1a
Autor:
Esmaeel Babaeenezhad, Fakhraddin Naghibalhossaini, Masoumeh Rajabibazl, Zohreh Jangravi, Forouzan Hadipour Moradi, Mohammad Davood Fattahi, Jörg D. Hoheisel, Mostafa Moradi Sarabi, Soroosh Shahryarhesami
Publikováno v:
Non-Coding RNA, Vol 8, Iss 5, p 67 (2022)
Digestive tract cancers represent a serious public health issue. In recent years, evidence has accumulated that microRNA miR-185 is implicated in the pathogenesis of this group of highly malignant tumors. Its expression variations correlate with clin
Externí odkaz:
https://doaj.org/article/972dbb55c0004dfbab56d0d6f900fb92
Publikováno v:
Iranian Journal of Medical Sciences, Vol 44, Iss 5, Pp 397-405 (2019)
Background: Intense stress can change pain perception and induce hyperalgesia; a phenomenon called stress-induced hyperalgesia (SIH). However, the neurobiological mechanism of this effect remains unclear. The present study aimed to investigate the ef
Externí odkaz:
https://doaj.org/article/d3b6af9fde164d47af4fdae25890dccc
Autor:
Fakhraddin Naghibalhossaini, Marzieh Shefaghat, Amirata Mansouri, Hajar Jaberi, Mohsen Tatar, Ebrahim Eftekhar
Publikováno v:
Acta Medica Iranica, Vol 55, Iss 12 (2018)
5-fluorouracil (5-FU) is one of the major components of many standard regimens for chemotherapy of colorectal cancer (CRC) and some other malignancies. Given the known relationship between thymidylate synthase (TS) and methylenetetrahydrofolate reduc
Externí odkaz:
https://doaj.org/article/c22a4956ada140bcacd6b6fe0e1a38e4
Autor:
Pooneh Mokarram, Krishan Kumar, Hassan Brim, Fakhraddin Naghibalhossaini, Mehdi Saberi-firoozi, Mehdi Nouraie, Robert Green, Ed Lee, Duane T Smoot, Hassan Ashktorab
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e7012 (2009)
Mutations and promoters' methylation of a set of candidate cancer genes (CAN genes) are associated with progression of colorectal cancer (CRC). We hypothesized that these genes' promoters are inactivated through epigenetic silencing and may show a di
Externí odkaz:
https://doaj.org/article/62a8e5770fd3471084688cbdfcb0d6f7
Autor:
Mostafa Moradi Sarabi, Esmaeel Babaeenezhad, Maral Amini, Fakhraddin Naghibalhossaini, Mozhgan Kaviani
Publikováno v:
Endocrine, Metabolic & Immune Disorders - Drug Targets. 22:1178-1190
Bilirubin is the main waste product of heme catabolism. At high concentrations, bilirubin may cause toxicity, especially in the brain, kidney, and erythrocytes. Membrane and mitochondrial dysfunction, oxidative stress, apoptosis, necrosis, endoplasmi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deece04748e0f1042554a603dee2a40b
https://doi.org/10.2174/1871530321666211125102924
https://doi.org/10.2174/1871530321666211125102924
Publikováno v:
Nutrition and Cancer. 74:1446-1456
Fruit-derived polyphenolic compounds have been shown to exert anticancer effects via epigenetic mechanisms. In this study, we investigated the effect of blackberry extract on the expression of DNMTs (Dnmt1, Dnmt3a, and Dnmt3b) and HDACs (HDAC1-4 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89e5b3d9b6973663008b57511b451ec5
https://doi.org/10.1080/01635581.2021.1952454
https://doi.org/10.1080/01635581.2021.1952454
Publikováno v:
Journal of Surgical Research. 253:272-279
Background Mechanical ventilation (MV) is life saving; yet it may induce severe lung injury and lead to multisystem organ failure and death. Thyroid hormones (THs) promote alveolar fluid clearance and alleviates hypoxia-induced lung injury. Given tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cca5c212b0ffe515033ea55917e48afa
https://doi.org/10.1016/j.jss.2020.03.060
https://doi.org/10.1016/j.jss.2020.03.060
Autor:
Seyed Mohammad Hashem Hosseini, Mohammad Hadi Eskandari, Hadi Hashemi Gahruie, Fakhraddin Naghibalhossaini, Mohammad-Taghi Golmakani, Reza Zarei, Fatemeh Ghiasi
Publikováno v:
International journal of pharmaceutics. 610
This work aimed to develop a novel nanoencapsulation system for food colloidal formulations using gelled lipid nanoparticles (GLNs) to improve the functionality, stability, and bioactivity of cuminaldehyde as a highly volatile and poor hydrophilic fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3e26c3ab24902b37899c46eac8ac3aa
https://pubmed.ncbi.nlm.nih.gov/34752917
https://pubmed.ncbi.nlm.nih.gov/34752917