Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Faizal A. M. Raffi"'
Autor:
Faizal A. M. Raffi, Roland Lang
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2710 (2019)
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2710 (2019)
Kinase activation and phosphorylation cascades are key to initiate immune cell activation in response to recognition of antigen and sensing of microbial danger. However, for balanced and controlled immune responses, the intensity and duration of phos
Autor:
Matthias Schiemann, Uwe K. Appelt, Tim Sparwasser, Ulrike Billmeier, Roland Lang, Stefan Wirtz, Stephen M. Keyse, Jurjen Tel, Sandra Muench, Faizal A. M. Raffi, Joerg Mages, Katrin Jozefowski, Carl G. Figdor, Hubertus Hochrein, Nour Alati, Katharina Lahl, Magdalena Niedzielska
Publikováno v:
Journal of Immunology, 195, 4, pp. 1753-62
Journal of Immunology, 195, 1753-62
Journal of Immunology, 195, 1753-62
Plasmacytoid dendritic cells (pDCs) efficiently produce large amounts of type I IFN in response to TLR7 and TLR9 ligands, whereas conventional DCs (cDCs) predominantly secrete high levels of the cytokines IL-10 and IL-12. The molecular basis underlyi