Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Faith V, Mayer"'
Autor:
Angela Woods, Jennet R. Williams, Phillip J. Muckett, Faith V. Mayer, Maria Liljevald, Mohammad Bohlooly-Y, David Carling
Publikováno v:
Cell Reports, Vol 18, Iss 13, Pp 3043-3051 (2017)
AMP-activated protein kinase (AMPK) plays a key role in integrating metabolic pathways in response to energy demand. We identified a mutation in the γ1 subunit (γ1D316A) that leads to activation of AMPK. We generated mice with this mutation to stud
Externí odkaz:
https://doaj.org/article/ef62f181128e4d0bbe4ebc25109d1987
Autor:
Angela, Woods, Jennet R, Williams, Phillip J, Muckett, Faith V, Mayer, Maria, Liljevald, Mohammad, Bohlooly-Y, David, Carling
Publikováno v:
Cell Reports
Summary AMP-activated protein kinase (AMPK) plays a key role in integrating metabolic pathways in response to energy demand. We identified a mutation in the γ1 subunit (γ1D316A) that leads to activation of AMPK. We generated mice with this mutation
Autor:
Roksana W. Ogrodowicz, Matthew J. Sanders, David Carling, Martin C. Schmidt, Fiona C. Leiper, Faith V. Mayer, Philip A. Walker, David Carmena, Bing Xiao, Chun Jing, Elizabeth Underwood, Steven J. Gamblin, Stephen R. Martin, Richard Heath, Rhonda R. McCartney, Lesley F. Haire
Publikováno v:
Cell Metabolism
Summary The SNF1 protein kinase complex plays an essential role in regulating gene expression in response to the level of extracellular glucose in budding yeast. SNF1 shares structural and functional similarities with mammalian AMP-activated protein
Autor:
Faith V. Mayer, Stephen R. Martin, David Carmena, Matthew J. Sanders, Bing Xiao, Rein Aasland, David Carling, Chun-Xia Jing, Steven Howell, Richard Heath, Peter Saiu, Elizabeth Underwood, Lesley F. Haire, John F. Eccleston, Steven J. Gamblin, Philip A. Walker
Publikováno v:
Nature
The heterotrimeric AMP-activated protein kinase (AMPK) has a key role in regulating cellular energy metabolism; in response to a fall in intracellular ATP levels it activates energy-producing pathways and inhibits energy-consuming processes. AMPK has