Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Faith Hollingsworth"'
Autor:
Julie M. Gastier-Foster, Fredrick Lutwama, Olive Mbabazi, Steven Mlenga, Kennedy Ulaya, Ruth Namazzi, E. Faith Hollingsworth, Dolores Lopez-Terrada, Kevin E. Fisher, Angshumoy Roy, Carl E. Allen, David G. Poplack, Rizine Mzikamanda, Nmazuo Ozuah, Peter Wasswa
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Risk stratification and molecular targeting have been key to increasing cure rates for pediatric cancers in high-income countries. In contrast, precise diagnosis in low-resource settings is hindered by insufficient pathology infrastructure. The Globa
Externí odkaz:
https://doaj.org/article/57f31e6043a84d179f230139c333fdd9
Autor:
Pavel Sumazin, Tricia L. Peters, Stephen F. Sarabia, Hyunjae R. Kim, Martin Urbicain, Emporia Faith Hollingsworth, Karla R. Alvarez, Cintia R. Perez, Alice Pozza, Mohammad Javad Najaf Panah, Jessica L. Epps, Kathy Scorsone, Barry Zorman, Howard Katzenstein, Allison F. O’Neill, Rebecka Meyers, Greg Tiao, Jim Geller, Sarangarajan Ranganathan, Arun A. Rangaswami, Sarah E. Woodfield, John A. Goss, Sanjeev A. Vasudevan, Andras Heczey, Angshumoy Roy, Kevin E. Fisher, Rita Alaggio, Kalyani R. Patel, Milton J. Finegold, Dolores H. López-Terrada
Publikováno v:
Journal of hepatology. 77(4)
Hepatoblastoma (HB) and hepatocellular carcinoma (HCC) are the predominant liver cancers in children, though their respective treatment options and associated outcomes differ dramatically. Risk stratification using a combination of clinical, histolog
Autor:
Julie M. Gastier-Foster, E. Faith Hollingsworth, Dolores H. Lopez-Terrada, Kevin E. Fisher, Angshumoy Roy, Peter M. Wasswa, Nmazuo W. Ozuah, Parth Mehta, Joseph Lubega, Carl E. Allen, David G. Poplack, Fredrick Lutwama
Publikováno v:
Cancer Research. 82:1021-1021
The extreme disparity in pediatric cancer outcomes in low- and middle-income countries (LMICs, 20%) vs. the US (80%) can only be solved by addressing the inequities of access to high quality healthcare, including a precise diagnosis. In the US, excel
Autor:
D. Williams Parsons, Nipun Kakkar, Ilavarasi Gandhi, Priya Mahajan, Faith Hollingsworth, Ioanna D. Athanassaki, Koel Sen Baksi, Rajkumar Venkatramani, Dolores Lopez-Terrada, Angshumoy Roy, Daniel C. Chelius, Monica E. Lopez, Samara L. Potter, Raghu Chandramohan, Jacquelyn Reuther, Stephen F. Sarabia, Norma M. Quintanilla, Horatiu Voicu, Hadi Sayeed
Publikováno v:
Pediatric bloodcancerREFERENCES. 68(1)
Background Pediatric papillary thyroid carcinoma (PTC) is clinically and biologically distinct from adult PTC. We sequenced a cohort of clinically annotated pediatric PTC cases enriched for high-risk tumors to identify genetic alterations of relevanc
Autor:
Jared Jakacky, Nimesh R. Patel, Faith Hollingsworth, Hadi Sayeed, Andre M. Oliveira, Brian P. Rubin, Alaa A. Salim, Alexander J. Lazar, Stephen F. Sarabia, Munir R. Tanas, Mikako Warren, Dolores Lopez-Terrada, Wei Lien Wang
Publikováno v:
Histopathology. 67:699-708
Aims Epithelioid haemangioendothelioma (EHE) is a malignant vascular neoplasm. Subsets have been characterized previously by translocations resulting in either WWTR1–CAMTA1 or YAP1–TFE3 fusion. We sought to develop molecular and immunohistochemic
Autor:
Ichiro Nakano, Daniel P. Cahill, Kaushal Joshi, Nina Lelic, Faith Hollingsworth, Hendrikus Boddeke, Adriana Olar, Christopher E. Pelloski, Joy Gumin, Frederick F. Lang, Wilfred F. A. den Dunnen, Se Hoon Kim, Erik P. Sulman, Heidi S. Phillips, Howard Colman, Lihong Long, Khalida Wani, Ganesh Rao, Brian Vaillant, Johanna D. James, Suzhen Wang, Siobhan Conroy, Ravesanker Ezhilarasan, Aditya Raghunathan, Karlijn Hummelink, Lindsey Heathcock, Yoshinori Kodama, Krishna P.L. Bhat, Lindsey D. Goodman, Divya Raj, Amy B. Heimberger, Veerakumar Balasubramaniyan, Kenneth Aldape
Publikováno v:
Cancer cell, 24(3), 331-346. CELL PRESS
Despite extensive study, few therapeutic targets have been identified for glioblastoma (GBM). Here we show that patient-derived glioma sphere cultures (GSCs) that resemble either the proneural (PN) or nnesenchymal (MES) transcriptomal subtypes differ
Autor:
Kenneth Aldape, Dongmin Gu, Hong Ji, Pierre D. McCrea, Nam K. Tonthat, Moonsup Lee, Thomas P. Zwaka, Faith Hollingsworth, Krishna P. Bhat, Maria A. Schumacher
Publikováno v:
Journal of Biological Chemistry. 286:23178-23188
δ-Catenin is an Armadillo protein of the p120-catenin subfamily capable of modulating cadherin stability, small GTPase activity, and nuclear transcription. From yeast two-hybrid screening of a human embryonic stem cell cDNA library, we identified δ
Autor:
Horatiu Voicu, Monica E. Lopez, Stephen F. Sarabia, Faith Hollingsworth, Angshumoy Roy, Dolores Lopez-Terrada, Norma M. Quintanilla, Jacquelyn Reuther, Samara L. Potter, Ioanna D. Athanassaki, Donald W. Parsons, Hadi Sayeed, Rajkumar Venkatramani, Nipun Kakkar, Koel Sen Baksi, Daniel C. Chelius, Ilavarasi Gandhi
Publikováno v:
Cancer Research. 78:A36-A36
Background: Papillary thyroid carcinomas (PTC) comprise 90% of thyroid cancers in children. Pediatric PTC is known to be clinically and biologically different than adult PTC, with pediatric tumors more likely to present with metastases and less likel
Autor:
Ryuji Kobayashi, Kenneth Aldape, Seiji Kondo, E. Faith Hollingsworth, Yasuko Kondo, Naoki Shinojima, Oliver Bogler, Yutaka Tamada, Akitsugu Yamamoto, Eiji Iwado, Hiroshi Aoki, Li Zhang, Charles A. Conrad, Tomohisa Yokoyama, Takashi Shingu, Gordon B. Mills, Kenneth R. Hess, Raymond Sawaya
Publikováno v:
Autophagy. 4:467-475
Autophagy, an evolutionarily conserved response to stress, has recently been implicated in cancer initiation and progression, but the detailed mechanisms and functions have not yet been fully elucidated. One major obstacle to our understanding is lac
Autor:
Johanna D. James, Erik P. Sulman, Frederick F. Lang, Tiffany Doucette, Alice Turski, Brian Vaillant, Se Hoon Kim, Katrina Salazar, Howard Colman, Veerakumar Balasubramaniyan, Lindsey Heathcock, Ganesh Rao, Yuhui Yang, Kristin Diefes, Sjef Copray, Krishna P.L. Bhat, Kenneth Aldape, Khalida Wani, Yasaman Azodi, Faith Hollingsworth, Joy Gumin
Publikováno v:
Genes & Development, 25(24), 2594-2609. COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
Recent molecular classification of glioblastoma (GBM) has shown that patients with a mesenchymal (MES) gene expression signature exhibit poor overall survival and treatment resistance. Using regulatory network analysis of available expression microar