Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Faith Hassinger"'
Autor:
Don S. Dizon, Katina Robison, Shannon Diane MacLaughlan David, Jason T Machan, Matthew James Hadfield, Eric I Marks, Rani Chudasama, Tarra Evans, Mary Lorraine Lopresti, Emma Safran, Michaela Kastura, Faith Hassinger, Ashlee Sturtevant, Roxanne Wood, Alexi A. Wright, Rochelle Strenger, Ursula A. Matulonis, Christina Bandera, Susana M. Campos, Michael J. Birrer
Publikováno v:
Journal of Clinical Oncology. 40:5598-5598
5598 Background: Clear Cell Carcinoma (CCC) outside the kidney is a rare tumor that can arise from multiple organs, including the ovary, endometrium and cervix. Extra-renal CCC is chemoresistant and has a poor prognosis. Data suggest that CCC of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::701a4e213435234d1309662712c183eb
https://doi.org/10.1200/jco.2022.40.16_suppl.5598
https://doi.org/10.1200/jco.2022.40.16_suppl.5598
Autor:
Amber Scotton, Brian Beardslee, Khanh T. Do, Geoffrey I. Shapiro, Sheelagh Frame, Solida Pruitt-Thompson, Daniella Zheleva, Ketki Bhushan, Nicole G. Chau, David Blake, Andrew Wolanski, Judy H. Chiao, Faith Hassinger
Publikováno v:
Cancer Research. 78:CT037-CT037
Background: CYC065 is a potent and selective inhibitor of CDK2 and CDK9. CDK2 drives cell cycle transition and activates major DNA double-strand break repair pathways; CDK9 regulates transcription of genes through phosphorylation of RNAP II. This fir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cd37af4885da326f36a1f76a55f684b
https://doi.org/10.1158/1538-7445.am2018-ct037
https://doi.org/10.1158/1538-7445.am2018-ct037
Autor:
Solida Pruitt-Thompson, Geoffrey I. Shapiro, Leena Gandi, Bruce E. Johnson, Faith Hassinger, Geoffrey R. Oxnard, James M. Cleary, Alona Muzikansky, Ketki Bhushan, Kwok-Kin Wong, Nicole G. Chau, Elizabeth Downey, John Hilton, Andrew Wolanski, Jeffrey G. Supko, Adrienne Anderson, Joseph W. Gibson, Nora Feeney, Suzanne M. Barry, Cloud P. Paweletz, Pasi A. Jänne, Brian Beardslee
Publikováno v:
Cancer Research. 77:CT046-CT046
Background: Both MEK and CDK4/6 have been investigated as therapeutic targets in preclinical models of RAS mutant solid tumors. Multiple mechanisms contribute to synergism including the development of MAP kinase-dependence in RAS mutant cells exposed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f99ef92a955925fcbea941593d7f3f9b
https://doi.org/10.1158/1538-7445.am2017-ct046
https://doi.org/10.1158/1538-7445.am2017-ct046
Autor:
Khanh T. Do, Suzanne M. Barry, James M. Cleary, Bose Kochupurakkal, Dongpo Cai, Sara M. Tolaney, Andrew Wolanski, Solida Pruitt-Thompson, John Hilton, Jeffrey G. Supko, Elizabeth Downey, Alan D. D'Andrea, Richard Piekarz, Joseph Geradts, Geoffrey I. Shapiro, L. Austin Doyle, Alona Muzikansky, Ketki Bhushan, Christine Unitt, Brian Beardslee, Faith Hassinger
Publikováno v:
Cancer Research. 77:CT047-CT047
Background: Although PARP inhibition is effective against HR repair-deficient cancers, efficacy is limited by HR proficiency, whether present de novo or as a result of acquired resistance, prompting HR disrupting strategies to sensitize tumor cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56125646a3bead97bdf9334c70222f9a
https://doi.org/10.1158/1538-7445.am2017-ct047
https://doi.org/10.1158/1538-7445.am2017-ct047