Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Faith H A Osier"'
Autor:
Gathoni Kamuyu, Christian Bottomley, James Mageto, Brett Lowe, Patricia P Wilkins, John C Noh, Thomas B Nutman, Anthony K Ngugi, Rachael Odhiambo, Ryan G Wagner, Angelina Kakooza-Mwesige, Seth Owusu-Agyei, Kenneth Ae-Ngibise, Honorati Masanja, Faith H A Osier, Peter Odermatt, Charles R Newton, Study of Epidemiology of Epilepsy in Demographic Sites (SEEDS) group
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 5, p e2908 (2014)
Epilepsy is common in developing countries, and it is often associated with parasitic infections. We investigated the relationship between exposure to parasitic infections, particularly multiple infections and active convulsive epilepsy (ACE), in fiv
Externí odkaz:
https://doaj.org/article/b8d855699a6a441ba6cc68dbf1d5e7ec
Autor:
George M Warimwe, Linda M Murungi, Gathoni Kamuyu, George M Nyangweso, Juliana Wambua, Vivek Naranbhai, Helen A Fletcher, Adrian V S Hill, Philip Bejon, Faith H A Osier, Kevin Marsh
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57320 (2013)
Plasmodium falciparum malaria remains a major cause of illness and death in sub-Saharan Africa. Young children bear the brunt of the disease and though older children and adults suffer relatively fewer clinical attacks, they remain susceptible to asy
Externí odkaz:
https://doaj.org/article/6121631c297b4fee8a9870abcf44e77d
Autor:
Philip Bejon, Thomas N Williams, Anne Liljander, Abdisalan M Noor, Juliana Wambua, Edna Ogada, Ally Olotu, Faith H A Osier, Simon I Hay, Anna Färnert, Kevin Marsh
Publikováno v:
PLoS Medicine, Vol 7, Iss 7, p e1000304 (2010)
BackgroundInfectious diseases often demonstrate heterogeneity of transmission among host populations. This heterogeneity reduces the efficacy of control strategies, but also implies that focusing control strategies on "hotspots" of transmission could
Externí odkaz:
https://doaj.org/article/6784a10e6a1e4030a6dc307c291beb26
Autor:
Federica Verra, Jacques Simpore, George M Warimwe, Kevin K Tetteh, Tevis Howard, Faith H A Osier, Germana Bancone, Pamela Avellino, Isa Blot, Greg Fegan, Peter C Bull, Thomas N Williams, David J Conway, Kevin Marsh, David Modiano
Publikováno v:
PLoS ONE, Vol 2, Iss 10, p e978 (2007)
A recently proposed mechanism of protection for haemoglobin C (HbC; beta6Glu-->Lys) links an abnormal display of PfEMP1, an antigen involved in malaria pathogenesis, on the surface of HbC infected erythrocytes together with the observation of reduced
Externí odkaz:
https://doaj.org/article/0eb468f537e74a9e9f43c2d67416f3bf
Autor:
Rodney Ogwang, Lewis Murugu, Irene N. Nkumama, Lydia Nyamako, Oscar Kai, Kennedy Mwai, Linda Murungi, Richard Idro, Philip Bejon, James Tuju, Sam Muchina Kinyanjui, Faith H. A. Osier
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundMalaria remains a major global health priority, and monoclonal antibodies (mAbs) are emerging as potential new tools to support efforts to control the disease. Recent data suggest that Fc-dependent mechanisms of immunity are important media
Externí odkaz:
https://doaj.org/article/3596a9cc7bec4318b00e63734a832347
Autor:
Doreen D. Mutemi, James Tuju, Rodney Ogwang, Lydia Nyamako, Kennedy M. Wambui, Ivette R. Cruz, Pär Villner, Victor Yman, Samson M. Kinyanjui, Ingegerd Rooth, Billy Ngasala, Anna Färnert, Faith H. A. Osier
Publikováno v:
Vaccines, Vol 12, Iss 2, p 203 (2024)
Malaria transmission intensity affects the development of naturally acquired immunity to malaria. An absolute correlate measure of protection against malaria is lacking. However, antibody-mediated functions against Plasmodium falciparum correlate wit
Externí odkaz:
https://doaj.org/article/b268b86836494599a872943934959601
Autor:
Fauzia K. Musasia, Irene N. Nkumama, Roland Frank, Victor Kipkemboi, Martin Schneider, Kennedy Mwai, Dennis O. Odera, Micha Rosenkranz, Kristin Fürle, Domitila Kimani, James Tuju, Patricia Njuguna, Mainga Hamaluba, Melissa C. Kapulu, Hedda Wardemann, CHMI-SIKA Study Team, Faith H. A. Osier
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Here the authors show that antibody-dependent phagocytosis of ring-stage P. falciparum parasites is mediated by merozoite antigens and is a strong predictor of protection following challenge in a controlled human malaria infection study in semi-immun
Externí odkaz:
https://doaj.org/article/05eca205b64046bc81c04d229ecba544
Autor:
Karamoko Niaré, Timothy Chege, Micha Rosenkranz, Kennedy Mwai, Zoe Saßmannshausen, Dennis Odera, Lydia Nyamako, James Tuju, Tiono Alfred, John N. Waitumbi, Bernhards Ogutu, Sodiomon B. Sirima, Gordon Awandare, Bourema Kouriba, Julian C. Rayner, Faith H. A. Osier
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionDetailed analyses of genetic diversity, antigenic variability, protein localization and immunological responses are vital for the prioritization of novel malaria vaccine candidates. Comprehensive approaches to determine the most appropria
Externí odkaz:
https://doaj.org/article/8bd727a934b34249bd207e4d4cb957a2
Autor:
Victor Yman, James Tuju, Michael T. White, Gathoni Kamuyu, Kennedy Mwai, Nelson Kibinge, Muhammad Asghar, Christopher Sundling, Klara Sondén, Linda Murungi, Daniel Kiboi, Rinter Kimathi, Timothy Chege, Emily Chepsat, Patience Kiyuka, Lydia Nyamako, Faith H. A. Osier, Anna Färnert
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Nature Communications
Nature Communications
Strengthening malaria surveillance is a key intervention needed to reduce the global disease burden. Reliable serological markers of recent malaria exposure could improve current surveillance methods by allowing for accurate estimates of infection in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::124b2bdb33008dd6f83964e3e010f60f
https://doaj.org/article/d52d616fbfd049d7ab986c391d76b171
https://doaj.org/article/d52d616fbfd049d7ab986c391d76b171
Autor:
Nelson Kibinge, Eustasius Musenge, Gathoni Kamuyu, Samson M. Kinyanjui, Timothy Chege, James Tuju, Kennedy Mwai, Emily Chepsat, Lydia Nyamako, James Mburu, Faith H. A. Osier, Rinter Kimathi, Irene Nkumama
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 2518-2525 (2021)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal
Graphical abstract
Protein microarrays are versatile tools for high throughput study of the human proteome, but systematic and non-systematic sources of bias constrain optimal interpretation and the ultimate utility of the data. Published guidel
Protein microarrays are versatile tools for high throughput study of the human proteome, but systematic and non-systematic sources of bias constrain optimal interpretation and the ultimate utility of the data. Published guidel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2405914bf151bb124bbd1588b569225
http://www.sciencedirect.com/science/article/pii/S2001037021001562
http://www.sciencedirect.com/science/article/pii/S2001037021001562