Zobrazeno 1 - 10
of 695
pro vyhledávání: '"Faith H"'
Autor:
Rodney Ogwang, Lewis Murugu, Irene N. Nkumama, Lydia Nyamako, Oscar Kai, Kennedy Mwai, Linda Murungi, Richard Idro, Philip Bejon, James Tuju, Sam Muchina Kinyanjui, Faith H. A. Osier
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundMalaria remains a major global health priority, and monoclonal antibodies (mAbs) are emerging as potential new tools to support efforts to control the disease. Recent data suggest that Fc-dependent mechanisms of immunity are important media
Externí odkaz:
https://doaj.org/article/3596a9cc7bec4318b00e63734a832347
Autor:
Doreen D. Mutemi, James Tuju, Rodney Ogwang, Lydia Nyamako, Kennedy M. Wambui, Ivette R. Cruz, Pär Villner, Victor Yman, Samson M. Kinyanjui, Ingegerd Rooth, Billy Ngasala, Anna Färnert, Faith H. A. Osier
Publikováno v:
Vaccines, Vol 12, Iss 2, p 203 (2024)
Malaria transmission intensity affects the development of naturally acquired immunity to malaria. An absolute correlate measure of protection against malaria is lacking. However, antibody-mediated functions against Plasmodium falciparum correlate wit
Externí odkaz:
https://doaj.org/article/b268b86836494599a872943934959601
Autor:
Faith H. Brennan, Yang Li, Cankun Wang, Anjun Ma, Qi Guo, Yi Li, Nicole Pukos, Warren A. Campbell, Kristina G. Witcher, Zhen Guan, Kristina A. Kigerl, Jodie C. E. Hall, Jonathan P. Godbout, Andy J. Fischer, Dana M. McTigue, Zhigang He, Qin Ma, Phillip G. Popovich
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Here the authors show, using microglia-specific depletion techniques and single cell transcriptomics, that optimal repair after murine spinal cord injury (SCI) requires microglia.
Externí odkaz:
https://doaj.org/article/c71897bb4488416ab0aceb965a3c158b
Autor:
Fauzia K. Musasia, Irene N. Nkumama, Roland Frank, Victor Kipkemboi, Martin Schneider, Kennedy Mwai, Dennis O. Odera, Micha Rosenkranz, Kristin Fürle, Domitila Kimani, James Tuju, Patricia Njuguna, Mainga Hamaluba, Melissa C. Kapulu, Hedda Wardemann, CHMI-SIKA Study Team, Faith H. A. Osier
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Here the authors show that antibody-dependent phagocytosis of ring-stage P. falciparum parasites is mediated by merozoite antigens and is a strong predictor of protection following challenge in a controlled human malaria infection study in semi-immun
Externí odkaz:
https://doaj.org/article/05eca205b64046bc81c04d229ecba544
Autor:
Karamoko Niaré, Timothy Chege, Micha Rosenkranz, Kennedy Mwai, Zoe Saßmannshausen, Dennis Odera, Lydia Nyamako, James Tuju, Tiono Alfred, John N. Waitumbi, Bernhards Ogutu, Sodiomon B. Sirima, Gordon Awandare, Bourema Kouriba, Julian C. Rayner, Faith H. A. Osier
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionDetailed analyses of genetic diversity, antigenic variability, protein localization and immunological responses are vital for the prioritization of novel malaria vaccine candidates. Comprehensive approaches to determine the most appropria
Externí odkaz:
https://doaj.org/article/8bd727a934b34249bd207e4d4cb957a2
Autor:
Victor Yman, James Tuju, Michael T. White, Gathoni Kamuyu, Kennedy Mwai, Nelson Kibinge, Muhammad Asghar, Christopher Sundling, Klara Sondén, Linda Murungi, Daniel Kiboi, Rinter Kimathi, Timothy Chege, Emily Chepsat, Patience Kiyuka, Lydia Nyamako, Faith H. A. Osier, Anna Färnert
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Serological markers of recent Plasmodium falciparum infection could be useful to estimate incidence. Here, the authors identify a combination of five serological markers to detect exposure to infection within the previous three months with >80% sensi
Externí odkaz:
https://doaj.org/article/d52d616fbfd049d7ab986c391d76b171
Publikováno v:
BMC Microbiology, Vol 20, Iss 1, Pp 1-16 (2020)
Abstract Background The production of methane by methanogens is dependent on numerous iron-sulfur (Fe-S) cluster proteins; yet, the machinery involved in Fe-S cluster biogenesis in methanogens remains largely unknown. Methanogen genomes encode unchar
Externí odkaz:
https://doaj.org/article/ccedc92bd4584154975087fbd8309cd7
Autor:
Randall S. Carpenter, Jessica M. Marbourg, Faith H. Brennan, Katherine A. Mifflin, Jodie C. E. Hall, Roselyn R. Jiang, Xiaokui M. Mo, Malith Karunasiri, Matthew H. Burke, Adrienne M. Dorrance, Phillip G. Popovich
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Spinal cord injury (SCI) often leads to immune dysfunction, but mechanistic insights are still lacking. Here the authors show that SCI alters chemokine signaling and induces long, persisting defects in hematopoietic stem and progenitor cell migration
Externí odkaz:
https://doaj.org/article/0d1de6f876b2431485cb553f43443b20
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/b81bbb63f96547db8bf32bb7bd49c8c7
Autor:
Faith H. N. Howard, Amy Kwan, Natalie Winder, Amina Mughal, Cristal Collado-Rojas, Munitta Muthana
Publikováno v:
Viruses, Vol 14, Iss 7, p 1493 (2022)
Emerging and re-emerging viral diseases have increased in number and geographical extent during the last decades. Examples include the current COVID-19 pandemic and the recent epidemics of the Chikungunya, Ebola, and Zika viruses. Immune responses to
Externí odkaz:
https://doaj.org/article/5e73d6f025a34d49a7f743cb47aba781