Zobrazeno 1 - 10
of 189
pro vyhledávání: '"Faisel Khan"'
Autor:
Kunihiko Aizawa, Alun D. Hughes, Francesco Casanova, Kim M. Gooding, Phillip E. Gates, David M. Mawson, Jennifer Williams, Isabel Goncalves, Jan Nilsson, Faisel Khan, Helen M. Colhoun, Carlo Palombo, Kim H. Parker, Angela C. Shore
Publikováno v:
ESC Heart Failure, Vol 11, Iss 5, Pp 3290-3298 (2024)
Abstract Aims Parameters derived from reservoir‐excess pressure analysis have been demonstrated to predict cardiovascular events. Thus, altered reservoir‐excess pressure parameters could have a detrimental effect on highly‐perfused organs like
Externí odkaz:
https://doaj.org/article/90221f9627714e60b5164d980c6f572e
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109077- (2024)
Summary: Laser speckle contrast imaging (LSCI) is an important non-invasive capability for real-time imaging for tissue-perfusion assessment. Yet, the size and weight of current clinical standard LSCI instrumentation restricts usage to mainly periphe
Externí odkaz:
https://doaj.org/article/d6cab2f413444360896f4b14918bf3eb
Autor:
Zhen Hui Peh, Adel Dihoum, Dana Hutton, J. Simon C. Arthur, Graham Rena, Faisel Khan, Chim C. Lang, Ify R. Mordi
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Heart failure with preserved ejection fraction (HFpEF) accounts for around half of all cases of heart failure and may become the dominant type of heart failure in the near future. Unlike HF with reduced ejection fraction there are few evidence-based
Externí odkaz:
https://doaj.org/article/d0e1aa5fca884514b08614539715dcd2
Publikováno v:
BMJ Open, Vol 13, Iss 6 (2023)
Introduction People who inject drugs are at risk of a range of injecting-related infections and injuries, which can threaten life and limb. In parallel to escalating rates of drug-related deaths seen in Scotland and the UK, there has also been an inc
Externí odkaz:
https://doaj.org/article/37bc6284e508432085694d8e07581014
Autor:
Chuanyan Wu, Yan Borné, Rui Gao, Maykel López Rodriguez, William C. Roell, Jonathan M. Wilson, Ajit Regmi, Cheng Luan, Dina Mansour Aly, Andreas Peter, Jürgen Machann, Harald Staiger, Andreas Fritsche, Andreas L. Birkenfeld, Rongya Tao, Robert Wagner, Mickaël Canouil, Mun-Gwan Hong, Jochen M. Schwenk, Emma Ahlqvist, Minna U. Kaikkonen, Peter Nilsson, Angela C. Shore, Faisel Khan, Andrea Natali, Olle Melander, Marju Orho-Melander, Jan Nilsson, Hans-Ulrich Häring, Erik Renström, Claes B. Wollheim, Gunnar Engström, Jianping Weng, Ewan R. Pearson, Paul W. Franks, Morris F. White, Kevin L. Duffin, Allan Arthur Vaag, Markku Laakso, Norbert Stefan, Leif Groop, Yang De Marinis
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Follistatin promotes in type 2 diabetes (T2D) pathogenesis in model animals and is elevated in patients with T2D. Here the authors report that plasma follistatin associates with increased risk of incident T2D in two longitudinal cohorts, and show tha
Externí odkaz:
https://doaj.org/article/718976e80f5648f99659b5ea904f47e5
Autor:
Annelie Shami, Andreas Edsfeldt, Eva Bengtsson, Jan Nilsson, Angela C. Shore, Andrea Natali, Faisel Khan, Esther Lutgens, Isabel Gonçalves
Publikováno v:
Journal of Stroke, Vol 23, Iss 3, Pp 367-376 (2021)
Background and Purpose CD40 and CD40 ligand (CD40L) are costimulatory molecules of the tumor necrosis factor receptor superfamily and well known for their involvement in inflammatory diseases: atherosclerotic mouse models with disrupted CD40 signalli
Externí odkaz:
https://doaj.org/article/a59fad5770eb4319b4cb7cdafcbcb201
Autor:
Abdulmalik Zuhair Arab, Aldo Alberto Conti, Fleur Davey, Faisel Khan, Alexander Mario Baldacchino
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Introduction: In 2019, Scotland reported the highest number of drug deaths amongst EU countries. Of the 1,264 drug deaths reported in 2019, 94% were related to polysedative use. Studies have proposed a relationship between opioid use and cardiovascul
Externí odkaz:
https://doaj.org/article/a851ea49acd54409b1cbc6a84a94425b
Publikováno v:
BMC Neurology, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Background Cholinesterase inhibitors remain the first line therapy for people with mild to moderate Alzheimer’s disease (AD). Response is modest and difficult to predict from pre-treatment characteristics. We hypothesise that skin vascular
Externí odkaz:
https://doaj.org/article/1cb30457f67e47fcbd7599c2d3d166fd
Autor:
Shaween Al-Talabany, Ify Mordi, J. Graeme Houston, Helen M. Colhoun, Jonathan R. Weir-McCall, Shona Z. Matthew, Helen C. Looker, Daniel Levin, Jill J. F. Belch, Fiona Dove, Faisel Khan, Chim C. Lang
Publikováno v:
BMC Cardiovascular Disorders, Vol 18, Iss 1, Pp 1-8 (2018)
Abstract Background Epicardial adipose tissue (EAT) is an emerging cardio-metabolic risk factor and has been shown to correlate with adverse cardiovascular (CV) outcome; however the underlying pathophysiology of this link is not well understood. The
Externí odkaz:
https://doaj.org/article/e5ad439aea454f3e92d284483ef7c099
Autor:
Naveed Akbar, Calum Forteath, Muhammad S. Hussain, Kathleen Reyskens, Jill J. F. Belch, Chim C. Lang, Ify R. Mordi, U Bhalraam, J. Simon C. Arthur, Faisel Khan
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8655 (2021)
Inflammation promotes endothelial dysfunction, but the underlying mechanisms remain poorly defined in vivo. Using translational vascular function testing in myocardial infarction patients, a situation where inflammation is prevalent, and knock-out (K
Externí odkaz:
https://doaj.org/article/5e2c6d8d4de347488f39e0cdac949974