Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Faisal A. Almobarak"'
Autor:
Altaf A. Kondkar, Taif A. Azad, Tahira Sultan, Tanvir Khatlani, Abdulaziz A. Alshehri, Rakesh Radhakrishnan, Glenn P. Lobo, Ehab Alsirhy, Faisal A. Almobarak, Essam A. Osman, Saleh A. Al-Obeidan
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4571 (2024)
This study investigated the association between apolipoprotein E (APOE) gene polymorphisms (rs429358 and rs7412) and primary angle-closure glaucoma (PACG) and pseudoexfoliation glaucoma (PXG) in a Saudi cohort. Genotyping of 437 DNA samples (251 cont
Externí odkaz:
https://doaj.org/article/81163c4d512d441389ca0071c424b805
Autor:
Altaf A. Kondkar, Tahira Sultan, Taif A. Azad, Tanvir Khatlani, Abdulaziz A. Alshehri, Essam A. Osman, Glenn P. Lobo, Faisal A. Almobarak, Saleh A. Al-Obeidan
Publikováno v:
Biology, Vol 13, Iss 1, p 62 (2024)
Adult-onset glaucoma, an age-related neurodegenerative disease, is very prevalent among the elderly Arabs of Saudi origin. This study investigated the association between apolipoprotein E (APOE) gene variants (rs429358 and rs7412) and primary open-an
Externí odkaz:
https://doaj.org/article/73e7913bcd2e45bf8e1220c6953c7163
Publikováno v:
BMC Ophthalmology, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Purpose To evaluate the visual outcome, intraocular pressure control and trabeculectomy survival after phacoemulsification in eyes with prior trabeculectomy in uveitis associated with Vogt-Koyanagi-Harada disease (VKH). Design Retrospective
Externí odkaz:
https://doaj.org/article/3c8cfd2920cd49bbb0f2ec5d3b0a97e7
Autor:
Altaf A. Kondkar, Taif A. Azad, Tahira Sultan, Essam A. Osman, Faisal A. Almobarak, Glenn P. Lobo, Saleh A. Al-Obeidan
Publikováno v:
PLoS ONE, Vol 18, Iss 4 (2023)
Aim In a retrospective and exploratory case-control study, we examined the genetic association of two common polymorphisms in the 3’ untranslated region (UTR) of DICER1 (rs3742330) and DROSHA (rs10719) genes in primary open-angle glaucoma (POAG) an
Externí odkaz:
https://doaj.org/article/f1c7fa910cbc42f38c071f8aafb1a75c
Autor:
Altaf A. Kondkar, Tahira Sultan, Taif A. Azad, Essam A. Osman, Faisal A. Almobarak, Glenn P. Lobo, Saleh A. Al-Obeidan
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Objective: It is plausible that common disease mechanisms exist in glaucoma pathophysiology. Accordingly, we investigated the genetic association of two previously reported primary open-angle glaucoma (POAG)-related gene polymorphisms, rs2472493 (A >
Externí odkaz:
https://doaj.org/article/fffa71bc0ef44173943b20844a5917d7
Autor:
Doaa S. Milibari, Dalal Fatani, Abeer Ahmad, Ohoud Owaidhah, Saleh A. AlObeidan, Faisal A. Almobarak, Rizwan Malik
Publikováno v:
BMC Ophthalmology, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background The use of a tissue patch graft is common practice with a glaucoma drainage device (GDD). Patch grafts can be visible in the palpebral fissure and may be cosmetically displeasing for some patients. The aim of this study was to rep
Externí odkaz:
https://doaj.org/article/61c61678a2d54d91b8358d91fdc95d0a
Autor:
Altaf A. Kondkar, Tahira Sultan, Taif A. Azad, Essam A. Osman, Faisal A. Almobarak, Saleh A. Al-Obeidan
Publikováno v:
BMC Medical Genetics, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background Glaucoma is a polygenic neurodegenerative disease and the second most common cause of blindness in Saudi Arabia. To test the hypothesis that genetic variants in the genes involved in the bone morphogenic protein (BMP) signaling pa
Externí odkaz:
https://doaj.org/article/cd6faad0b9334fa5a1835ac04cfdf7e0
Autor:
Altaf A. Kondkar, Taif A. Azad, Abdullah S. Alobaidan, Tahira Sultan, Essam A. Osman, Faisal A. Almobarak, Glenn P. Lobo, Saleh A. Al-Obeidan
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Objective: Recent studies have demonstrated an association of single nucleotide polymorphisms (SNPs) rs35934224 in TXNRD2 and rs6478746 near LMX1B genes in primary open-angle glaucoma (POAG) among Europeans. We performed a retrospective, case-control
Externí odkaz:
https://doaj.org/article/764365d3dfad4c9386bec4409559fa58
Autor:
Altaf A. Kondkar, Taif A. Azad, Tahira Sultan, Essam A. Osman, Faisal A. Almobarak, Saleh A. Al-Obeidan
Publikováno v:
Journal of Ophthalmology, Vol 2020 (2020)
Purpose. To determine the association between plasma 8-hydroxy-2′-deoxyguanosine (8-OHdG) levels, a marker for oxidative DNA damage, and patients with primary open-angle glaucoma (POAG) or its clinical phenotypes. Furthermore, we also examined the
Externí odkaz:
https://doaj.org/article/f5370fad22f647198037661817b44395
Autor:
Altaf A. Kondkar, Tahira Sultan, Faisal A. Almobarak, Hatem Kalantan, Khaled K. Abu-Amero, Saleh A. Al-Obeidan
Publikováno v:
BMC Research Notes, Vol 11, Iss 1, Pp 1-5 (2018)
Abstract Objective Plexin domain containing 2 (PLXDC2), a cell surface transmembrane protein receptor for pigment epithelium derived factor, is expressed in many tissues including the eye. Polymorphism rs7081455 flanking PLXDC2 has been associated wi
Externí odkaz:
https://doaj.org/article/2f2b8ed72624411e89063c53d65fcf55