Zobrazeno 1 - 10
of 4 207
pro vyhledávání: '"Fairlamb"'
Autor:
Sola, I., Castellà, S., Viayna, E., Galdeano, C., Taylor, M.C., Gbedema, Stephen Y., Pérez, B., Clos, M.V., Jones, D.C., Fairlamb, A.H., Wright, Colin W., Kelly, J.M., Muñoz-Torrero, D.
Yes
Dual submicromolar trypanocidal–antiplasmodial compounds have been identified by screening and chemical synthesis of 4-aminoquinoline-based heterodimeric compounds of three different structural classes. In Trypanosoma brucei, inhibition of
Dual submicromolar trypanocidal–antiplasmodial compounds have been identified by screening and chemical synthesis of 4-aminoquinoline-based heterodimeric compounds of three different structural classes. In Trypanosoma brucei, inhibition of
Externí odkaz:
http://hdl.handle.net/10454/7485
Autor:
Fulton, M. D., Smartt, S. J., Rhodes, L., Huber, M. E., Villar, A. V., Moore, T., Srivastav, S., Schultz, A. S. B., Chambers, K. C., Izzo, L., Hjorth, J., Chen, T. -W., Nicholl, M., Foley, R. J., Rest, A., Smith, K. W., Young, D. R., Sim, S. A., Bright, J., Zenati, Y., de Boer, T., Bulger, J., Fairlamb, J., Gao, H., Lin, C. -C., Lowe, T., Magnier, E. A., Smith, I. A., Wainscoat, R., Coulter, D. A., Jones, D. O., Kilpatrick, C. D., McGill, P., Ramirez-Ruiz, E., Lee, K. -S., Narayan, G., Ramakrishnan, V., Ridden-Harper, R., Singh, A., Wang, Q., Kong, A. K. H., Ngeow, C. -C., Pan, Y. -C., Yang, S., Davis, K. W., Piro, A. L., Rojas-Bravo, C., Sommer, J., Yadavalli, S. K.
We present extensive optical photometry of the afterglow of GRB~221009A. Our data cover $0.9 - 59.9$\,days from the time of \textit{Swift} and \textit{Fermi} GRB detections. Photometry in $rizy$-band filters was collected primarily with Pan-STARRS an
Externí odkaz:
http://arxiv.org/abs/2301.11170
Autor:
George E. Clarke, James D. Firth, Lyndsay A. Ledingham, Chris S. Horbaczewskyj, Richard A. Bourne, Joshua T. W. Bray, Poppy L. Martin, Jonathan B. Eastwood, Rebecca Campbell, Alex Pagett, Duncan J. MacQuarrie, John M. Slattery, Jason M. Lynam, Adrian C. Whitwood, Jessica Milani, Sam Hart, Julie Wilson, Ian J. S. Fairlamb
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Understanding complex reaction systems is critical in chemistry. While synthetic methods for selective formation of products are sought after, oftentimes it is the full reaction signature, i.e., complete profile of products/side-products, th
Externí odkaz:
https://doaj.org/article/a5dc7136380943219f63ebaaa909dd86
8-Methoxy-naphtho[2,3-b]thiophen-4,9-quinone, a non-competitive inhibitor of trypanothione reductase
Autor:
Zani Carlos L, Fairlamb Alan H
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 98, Iss 4, Pp 565-568 (2003)
The enzyme trypanothione reductase is a recognised drug target in trypanosomatids and has been used in the search of new compounds with potential activity against diseases such as leishmaniasis, Chagas disease and African trypanosomiasis. 8-Methoxy-n
Externí odkaz:
https://doaj.org/article/0f6844e4ae994ab097e2e68a9461bacb
Autor:
de Boer, T. J. L., Huber, M. E., Magnier, E. A., Onaka, P. M., Chambers, K. C., Lin, C. -C., Gao, H., Fairlamb, J., Wainscoat, R. J.
Using data from a year-long dedicated campaign to observe bright stars, we study the crosstalk channels present in the GPC1 camera. By analyzing these data, we construct a dataset that checks source stars on almost every CCD of every chip within the
Externí odkaz:
http://arxiv.org/abs/2201.10680
Autor:
Lorna M MacLean, Mark Ariyanayagam, Lalitha Sastry, Christy Paterson, Manu De Rycker, Alan H Fairlamb
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0300021 (2024)
Trypanosoma cruzi (T. cruzi) is the causative agent of Chagas' disease, a parasitic infection responsible for significant morbidity and mortality in Latin America. The current treatments have many serious drawbacks and new drugs are urgently required
Externí odkaz:
https://doaj.org/article/919309b6fde141f59c00805954a3d78a
Autor:
Jones, D. O., Foley, R. J., Narayan, G., Hjorth, J., Huber, M. E., Aleo, P. D., Alexander, K. D., Angus, C. R., Auchettl, K., Baldassare, V. F., Bruun, S. H., Chambers, K. C., Chatterjee, D., Coppejans, D. L., Coulter, D. A., DeMarchi, L., Dimitriadis, G., Drout, M. R., Engel, A., French, K. D., Gagliano, A., Gall, C., Hung, T., Izzo, L., Jacobson-Galán, W. V., Kilpatrick, C. D., Korhonen, H., Margutti, R., Raimundo, S. I., Ramirez-Ruiz, E., Rest, A., Rojas-Bravo, C., Siebert, M. R., Smartt, S. J., Smith, K. W., Terreran, G., Wang, Q., Wojtak, R., Agnello, A., Ansari, Z., Arendse, N., Baldeschi, A., Blanchard, P. K., Brethauer, D., Bright, J. S., Brown, J. S., deBoer, T. J. L., Dodd, S. A., Fairlamb, J. R., Grillo, C., Hajela, A., Hede, C., Kolborg, A. N., Law-Smith, J. A. P., Lin, C. -C., Magnier, E. A., Malanchev, K., Matthews, D., Mockler, B., Muthukrishna, D., Pan, Y. -C., Pfister, H., Ramanah, D. K., Rest, S., Sarangi, A., Schrøder, S. L., Stauffer, C., Stroh, M. C., Taggart, K. L., Tinyanont, S., Wainscoat, R. J.
Time domain science has undergone a revolution over the past decade, with tens of thousands of new supernovae (SNe) discovered each year. However, several observational domains, including SNe within days or hours of explosion and faint, red transient
Externí odkaz:
http://arxiv.org/abs/2010.09724
Autor:
Wichittanakom, C., Oudmaijer, R. D., Fairlamb, J. R., Mendigutía, I., Vioque, M., Ababakr, K. M.
Publikováno v:
MNRAS, 493, 234-249 (2020)
This work presents a spectroscopic study of 163 Herbig Ae/Be stars. Amongst these, we present new data for 30 objects. Stellar parameters such as temperature, reddening, mass, luminosity and age are homogeneously determined. Mass accretion rates are
Externí odkaz:
http://arxiv.org/abs/2001.05971