Transitioning single-cell genomics into the clinic.

Autor: Lim J; Cellular Science, Garvan Institute of Medical Research, Sydney, NSW, Australia.; Department of Oncology, St George Hospital, Sydney, NSW, Australia.; The Kinghorn Cancer Centre, St Vincent's Hospital, Sydney, NSW, Australia.; Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia., Chin V; Cellular Science, Garvan Institute of Medical Research, Sydney, NSW, Australia.; The Kinghorn Cancer Centre, St Vincent's Hospital, Sydney, NSW, Australia.; Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia., Fairfax K; School of Medicine, University of Tasmania, Hobart, Australia., Moutinho C; Cellular Science, Garvan Institute of Medical Research, Sydney, NSW, Australia., Suan D; Cellular Science, Garvan Institute of Medical Research, Sydney, NSW, Australia.; Westmead Clinical School, University of Sydney, Sydney, NSW, Australia., Ji H; School of Medicine, Stanford University, Palo Alto, CA, USA.; Stanford Genome Technology Center, Stanford University, Palo Alto, CA, USA., Powell JE; Cellular Science, Garvan Institute of Medical Research, Sydney, NSW, Australia. j.powell@garvan.org.au.; Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia. j.powell@garvan.org.au.; UNSW Cellular Genomics Futures Institute, University of New South Wales, Sydney, NSW, Australia. j.powell@garvan.org.au.

Publikováno v: Nature reviews. Genetics [Nat Rev Genet] 2023 Aug; Vol. 24 (8), pp. 573-584. Date of Electronic Publication: 2023 May 31.

Functional genomics for curation of variants in telomere biology disorder associated genes: A systematic review.

Autor: Nelson N; The Menzies Institute for Medical Research, College of Health and Medicine, The University of Tasmania, Hobart, Tasmania, Australia; Department of Molecular Medicine, The Royal Hobart Hospital, Hobart, Tasmania, Australia; Department of Molecular Haematology, The Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia. Electronic address: niles.nelson@utas.edu.au., Feurstein S; Section of Hematology, Oncology, and Rheumatology, Department of Internal Medicine, Heidelberg University Hospital, Heidelberg, Germany., Niaz A; Children's Medical Research Institute, Faculty of Medicine and Health, University of Sydney, Westmead, New South Wales, Australia., Truong J; School of Science, STEM College, RMIT University, Bundoora, Victoria, Australia., Holien JK; School of Science, STEM College, RMIT University, Bundoora, Victoria, Australia., Lucas S; The Menzies Institute for Medical Research, College of Health and Medicine, The University of Tasmania, Hobart, Tasmania, Australia., Fairfax K; The Menzies Institute for Medical Research, College of Health and Medicine, The University of Tasmania, Hobart, Tasmania, Australia., Dickinson J; The Menzies Institute for Medical Research, College of Health and Medicine, The University of Tasmania, Hobart, Tasmania, Australia., Bryan TM; Children's Medical Research Institute, Faculty of Medicine and Health, University of Sydney, Westmead, New South Wales, Australia.

Publikováno v: Genetics in medicine : official journal of the American College of Medical Genetics [Genet Med] 2023 Mar; Vol. 25 (3), pp. 100354. Date of Electronic Publication: 2022 Dec 07.

Absence of pro-survival A1 has no impact on inflammatory cell survival in vivo during acute lung inflammation and peritonitis.

Autor: Gangoda L; The Walter and Eliza Hall Institute of Medical Research (WEHI), Melbourne, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia.; La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia., Schenk RL; The Walter and Eliza Hall Institute of Medical Research (WEHI), Melbourne, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Best SA; The Walter and Eliza Hall Institute of Medical Research (WEHI), Melbourne, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Nedeva C; La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia., Louis C; The Walter and Eliza Hall Institute of Medical Research (WEHI), Melbourne, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., D'Silva DB; The Walter and Eliza Hall Institute of Medical Research (WEHI), Melbourne, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Fairfax K; The Walter and Eliza Hall Institute of Medical Research (WEHI), Melbourne, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia.; Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, Australia., Jarnicki AG; Department of Biochemistry and Pharmacology, University of Melbourne, Parkville, VIC, Australia., Puthalakath H; La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia., Sutherland KD; The Walter and Eliza Hall Institute of Medical Research (WEHI), Melbourne, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Strasser A; The Walter and Eliza Hall Institute of Medical Research (WEHI), Melbourne, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Herold MJ; The Walter and Eliza Hall Institute of Medical Research (WEHI), Melbourne, VIC, Australia. herold@wehi.edu.au.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia. herold@wehi.edu.au.

Publikováno v: Cell death and differentiation [Cell Death Differ] 2022 Jan; Vol. 29 (1), pp. 96-104. Date of Electronic Publication: 2021 Jul 24.

Loss of immune cell identity with age inferred from large atlases of single cell transcriptomes.

Autor: Connolly, Erin¹ (AUTHOR), Pan, Tony^2,3 (AUTHOR), Aluru, Maneesha² (AUTHOR), Chockalingam, Sriram² (AUTHOR), Dhere, Vishal⁴ (AUTHOR), Gibson, Greg¹ (AUTHOR) greg.gibson@biology.gatech.edu

Publikováno v: Aging Cell. Dec2024, Vol. 23 Issue 12, p1-15. 15p.

IL-4-Secreting secondary Tfh cells arise from memory T cells, not persisting Tfh cells, not persisting Tfh cells, through a B cell dependent mechanism

Autor: Fairfax, K., Everts, B., Amiel, E., Smith, A., Schramm, G., Haas, H., Randolph, G., Taylor, J., Pearce, E.

Publikováno v: The Journal of Immunology

Humoral immunity requires crosstalk between T follicular helper (Tfh) and B cells. Nevertheless, a detailed understanding of this intercellular interaction during secondary immune responses is lacking. We examined this by focusing on the response to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1874::75d3c4e2bbb16f2e0d9274f1af2c1435
https://hdl.handle.net/21.11116/0000-0006-A4DC-921.11116/0000-0006-A4DE-7