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of 60
pro vyhledávání: '"Fairfax BP"'
Autor:
Fairfax BP, Pratap S, Roberts ISD, Collier J, Kaplan R, Meade AM, Ritchie AW, Eisen T, Macaulay VM, Protheroe A
Publikováno v:
BMC Cancer, Vol 12, Iss 1, p 590 (2012)
Abstract Background Sorafenib is an orally available kinase inhibitor with activity at Raf, PDGFβ and VEGF receptors that is licensed for the treatment of advanced renal cell carcinoma (RCC) and hepatocellular carcinoma (HCC). Current evidence-based
Externí odkaz:
https://doaj.org/article/7d072e67bb5943888bb27b97591ff7dd
Autor:
Isar Nassiri, Fairfax Bp, Rosalin Cooper, A. Verge de Los Aires, Orion Tong, Sharma Pk, Mahé Ea, Watson Ra, Middleton Mr, Taylor Ca, Hélène Ruffieux
Immune checkpoint blockers (ICB) exert their anti-cancer effects via CD8+ T cells, although how responses vary over sub-populations and across clones is incompletely understood. We performed single-cell RNA-sequencing of CD8+ T cells and their recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7d124c4fec3096d597cc6f27165fcec
https://doi.org/10.1101/2020.11.15.383786
https://doi.org/10.1101/2020.11.15.383786
Autor:
Gilchrist, JJ, Rautanen, A, Fairfax, BP, Mills, TC, Naranbhai, V, Trochet, H, Pirinen, M, Muthumbi, E, Mwarumba, S, Njuguna, P, Mturi, N, Msefula, CL, Gondwe, EN, MacLennan, JM, Chapman, SJ, Molyneux, ME, Knight, JC, Spencer, CCA, Williams, TN, MacLennan, CA, Scott, JAG, Hill, AVS
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications
Nature Communications
Nontyphoidal Salmonella (NTS) is a major cause of bacteraemia in Africa. The disease typically affects HIV-infected individuals and young children, causing substantial morbidity and mortality. Here we present a genome-wide association study (180 case
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::3dbabe32d6fc98e198b4e8caf532df8c
http://link.springer.com/article/10.1038/s41467-017-02398-z
http://link.springer.com/article/10.1038/s41467-017-02398-z
Autor:
Simpson, NH, Addis, L, Brandler, WM, Slonims, V, Clark, A, Watson, J, Scerri, TS, Hennessy, ER, Bolton, PF, Conti-Ramsden, G, Fairfax, BP, Knight, JC, Stein, J, Talcott, JB, O'Hare, A, Baird, G, Paracchini, S, Fisher, SE, Newbury, DF
AIM: Sex chromosome aneuploidies increase the risk of spoken or written language disorders but individuals with specific language impairment (SLI) or dyslexia do not routinely undergo cytogenetic analysis. We assess the frequency of sex chromosome an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e86b41de9404a37a0eb15da12924ead2
https://ora.ox.ac.uk/objects/uuid:35f3b9a1-9f64-4867-a8f3-46271d28c7ac
https://ora.ox.ac.uk/objects/uuid:35f3b9a1-9f64-4867-a8f3-46271d28c7ac
Autor:
Simpson, NH, Addis, L, Brandler, WM, Slonims, V, Clark, A, Watson, J, Scerri, TS, Hennessy, ER, Bolton, PF, Conti-Ramsden, G, Fairfax, BP, Knight, JC, Stein, J, Talcott, JB, O'Hare, A, Baird, G, Paracchini, S, Fisher, SE, Newbury, DF, Nudel, R, Monaco, AP, Simonoff, E, Pickles, A, Everitt, A, Seckl, J, Cowie, H, Cohen, W, Nasir, J, Bishop, DVM, Simkin, Z
Publikováno v:
Developmental Medicine and Child Neurology. 56(4)
Aim: Sex chromosome aneuploidies increase the risk of spoken or written language disorders but individuals with specific language impairment (SLI) or dyslexia do not routinely undergo cytogenetic analysis. We assess the frequency of sex chromosome an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::c3993d789321c9e5de7e1e90a70ff92c
http://ora.ox.ac.uk/objects/uuid:d25e55ca-771b-495f-9989-04f85be2b81f
http://ora.ox.ac.uk/objects/uuid:d25e55ca-771b-495f-9989-04f85be2b81f
Akademický článek
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Autor:
Gilchrist JJ; Department of Paediatrics, University of Oxford, Oxford OX3 9DU, UK; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK., Fang H; Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Danielli S; Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Tomkova M; Ludwig Cancer Research Oxford, University of Oxford, Oxford OX3 7DQ, UK., Nassiri I; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK; Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Ng E; Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford OX3 7LD, UK., Tong O; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK., Taylor C; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK., Muldoon D; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK., Cohen LRZ; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK., Al-Mossawi H; Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford OX3 7LD, UK., Lau E; Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Neville M; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford OX3 7LE, UK., Schuster-Boeckler B; Ludwig Cancer Research Oxford, University of Oxford, Oxford OX3 7DQ, UK., Knight JC; Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Fairfax BP; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK; Department of Oncology, University of Oxford, Oxford OX3 9DS, UK. Electronic address: benjamin.fairfax@oncology.ox.ac.uk.
Publikováno v:
Cell genomics [Cell Genom] 2024 May 08; Vol. 4 (5), pp. 100541. Date of Electronic Publication: 2024 Apr 24.
Autor:
Watson RA; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.; Department of Oncology, University of Oxford, Oxford, UK.; Cancer and Haematology Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Ye W; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.; Department of Oncology, University of Oxford, Oxford, UK.; Cancer and Haematology Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Taylor CA; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.; Department of Oncology, University of Oxford, Oxford, UK., Jungkurth E; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.; Department of Oncology, University of Oxford, Oxford, UK., Cooper R; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.; Department of Oncology, University of Oxford, Oxford, UK., Tong O; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.; Department of Oncology, University of Oxford, Oxford, UK., James T; Department of Clinical Biochemistry, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Shine B; Department of Clinical Biochemistry, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Hofer M; Department of Neuro Pathology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Jenkins D; Department of Clinical Neurology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Pell R; Department of Cellular Pathology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Ieremia E; Department of Cellular Pathology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Jones S; Oxford Centre for Histopathological Research, Oxford University Hospitals NHS Trust, Oxford, UK., Maldonado-Perez D; Oxford Centre for Histopathological Research, Oxford University Hospitals NHS Trust, Oxford, UK., Roberts ISD; Department of Cellular Pathology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Coupe N; Cancer and Haematology Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Middleton MR; Department of Oncology, University of Oxford, Oxford, UK.; Cancer and Haematology Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Payne MJ; Cancer and Haematology Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Fairfax BP; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK benjamin.fairfax@oncology.ox.ac.uk.; Department of Oncology, University of Oxford, Oxford, UK.; Cancer and Haematology Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Publikováno v:
Journal for immunotherapy of cancer [J Immunother Cancer] 2024 Apr 24; Vol. 12 (4). Date of Electronic Publication: 2024 Apr 24.
Autor:
Chong AY; The Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK. Electronic address: amanda.chong@well.ox.ac.uk., Brenner N; Division of Infections and Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Jimenez-Kaufmann A; Advanced Genomics Unit, National Laboratory of Genomics for Biodiversity (LANGEBIO), CINVESTAV, Irapuato, Mexico., Cortes A; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK., Hill M; MRC-Population Health Research Unit, University of Oxford, Oxford, UK., Littlejohns TJ; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Gilchrist JJ; The Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK; Department of Paediatrics, University of Oxford, Oxford, UK., Fairfax BP; Department of Oncology, University of Oxford, Oxford, UK., Knight JC; The Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK; NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Hodel F; Global Health Institute, School of Life Sciences, EPFL, Lausanne, Switzerland; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Fellay J; Global Health Institute, School of Life Sciences, EPFL, Lausanne, Switzerland; Swiss Institute of Bioinformatics, Lausanne, Switzerland; Precision Medicine Unit, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., McVean G; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK., Moreno-Estrada A; Advanced Genomics Unit, National Laboratory of Genomics for Biodiversity (LANGEBIO), CINVESTAV, Irapuato, Mexico., Waterboer T; Division of Infections and Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Hill AVS; The Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK; The Jenner Institute, University of Oxford, Oxford, UK., Mentzer AJ; The Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK. Electronic address: alexander.mentzer@ndm.ox.ac.uk.
Publikováno v:
American journal of human genetics [Am J Hum Genet] 2024 Feb 01; Vol. 111 (2), pp. 295-308. Date of Electronic Publication: 2024 Jan 16.