Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Fai, Thomas G."'
Autor:
Bai, Xuesong, Fai, Thomas G.
Cell size varies between different cell types, and between different growth and osmotic conditions. However, the nuclear-to-cell volume ratio (N/C ratio) remains nearly constant. In this paper, we build on existing deterministic models of N/C ratio h
Externí odkaz:
http://arxiv.org/abs/2407.19066
In this paper, we model the configurations of a system of hard rods by viewing each rod in a cell formed by its neighbors. By minimizing the free energy in the model and performing molecular dynamics, where, in both cases, the shape of the cell is a
Externí odkaz:
http://arxiv.org/abs/2312.00239
Publikováno v:
Phys. Rev. Lett. 130, 128204 (2023)
We use a theoretical model to explore how fluid dynamics, in particular, the pressure gradient and wall shear stress in a channel, affect the deposition of particles flowing in a microfluidic network. Experiments on transport of colloidal particles i
Externí odkaz:
http://arxiv.org/abs/2210.01780
Publikováno v:
SIAM J. Appl. Mat., 84(3), S476-S492, 2024
The transport of particles in cells is influenced by the properties of intracellular networks they traverse while searching for localized target regions or reaction partners. Moreover, given the rapid turnover in many intracellular structures, it is
Externí odkaz:
http://arxiv.org/abs/2207.07682
Autor:
Zhang, Ying, Fai, Thomas G.
Publikováno v:
PLOS Comput. Biol., 19(7), e1011241, 2023
The geometry of the blood vessel wall plays a regulatory role on the motion of red blood cells (RBCs). The overall topography of the vessel wall depends on many features, among which the endothelial lining of the endothelial surface layer (ESL) is an
Externí odkaz:
http://arxiv.org/abs/2203.12113
Autor:
Kelly, Gess, Fai, Thomas G.
Publikováno v:
Proc. R. Soc. A., 478(2261), 20220119, 2022
We propose a coarse-grained theoretical model to capture the aging of microfluidic devices under different conditions including constant applied flow rate and constant applied pressure gradient. Microfluidic devices that sort cells by their deformabi
Externí odkaz:
http://arxiv.org/abs/2108.01570
Publikováno v:
SIAM J. Appl. Mat., 82(3), 793-820, 2022
We study the dynamics of membrane vesicle motor transport into dendritic spines, which are bulbous intracellular compartments in neurons that play a key role in transmitting signals between neurons. We consider the stochastic analog of the vesicle tr
Externí odkaz:
http://arxiv.org/abs/2107.07597
Publikováno v:
J. Nonlinear Sci., 31, 87, 2021
Within this work we derive and analyse an expression for the free energy of a single-species system in the thermodynamic limit in terms of a generalised cavity volume, that is exact in general, and in principle applicable to systems across their enti
Externí odkaz:
http://arxiv.org/abs/2104.15029
Publikováno v:
J. Chem. Phys., 154, 104505, 2021
We study packings of hard spheres on lattices. The partition function, and therefore the pressure, may be written solely in terms of the accessible free volume, i.e. the volume of space that a sphere can explore without touching another sphere. We co
Externí odkaz:
http://arxiv.org/abs/2011.07106
Autor:
Fai, Thomas G., Park, Youngmin
Publikováno v:
J. Math. Biol. 84, 8 (2022)
Organelle size control is a fundamental question in biology that demonstrates the fascinating ability of cells to maintain homeostasis within their highly variable environments. Theoretical models describing cellular dynamics have the potential to he
Externí odkaz:
http://arxiv.org/abs/2010.08163