Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Fahrettin, Haczeyni"'
Autor:
Fahrettin Haczeyni, Sandra Steensels, Benjamin D. Stein, James M. Jordan, Le Li, Vincent Dartigue, Selenay S. Sarklioglu, Jixuan Qiao, Xi K. Zhou, Andrew J. Dannenberg, Neil M. Iyengar, Haiyuan Yu, Lewis C. Cantley, Baran A. Ersoy
Publikováno v:
bioRxiv
Mitochondria-rich brown adipocytes dissipate cellular fuel as heat by thermogenic energy expenditure (TEE). Prolonged nutrient excess or cold exposure impair TEE and contribute to the pathogenesis of obesity, but the mechanisms remain incompletely un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd5204d46b6e6e663d2305ede515938
https://europepmc.org/articles/PMC10187325/
https://europepmc.org/articles/PMC10187325/
Autor:
Narcissus Teoh, Robert D. Goldin, George N. Ioannou, Matthew M. Yeh, Isabelle Leclercq, Geoffrey C. Farrell, Fahrettin Haczeyni, Yock Young Dan, Jun Yu
Publikováno v:
Journal of Gastroenterology and Hepatology. 33:1312-1320
Non-alcoholic steatohepatitis (NASH) is strongly associated with overnutrition, insulin resistance, and predisposition to type 2 diabetes. To critically analyze the translational significance of currently used animal models of NASH, we reviewed artic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0a6a69ec317cbfcf21f85e400c7f055
https://doi.org/10.1111/jgh.14122
https://doi.org/10.1111/jgh.14122
Autor:
Narcissus Teoh, Isabelle Leclercq, Vanessa Barn, W. Geoffrey Haigh, Geoffrey C. Farrell, Laurence Poekes, George N. Ioannou, Hans Wang, Fahrettin Haczeyni, Matthew M. Yeh, Auvro R. Mridha
Publikováno v:
Obesity. 25:155-165
Objective Nonalcoholic steatohepatitis (NASH) is the outcome of interactions between overnutrition, energy metabolism, and adipose function. Obeticholic acid (OCA) improves steatosis in patients but for unknown reasons does not resolve NASH pathology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4496a4da3ebed54d8552df7e80a835e6
https://doi.org/10.1002/oby.21701
https://doi.org/10.1002/oby.21701
Publikováno v:
Advances in experimental medicine and biology. 1061
Overnutrition, usually with obesity and genetic predisposition, lead to insulin resistance, which is an invariable accompaniment of nonalcoholic fatty liver disease (NAFLD). The associated metabolic abnormalities, pre- or established diabetes, hypert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0effeef6bda17db78483f7879eaff9c9
https://pubmed.ncbi.nlm.nih.gov/29956204
https://pubmed.ncbi.nlm.nih.gov/29956204
Autor:
Mark A. Febbraio, Vanessa Barn, Matthew M. Yeh, Kim S. Bell-Anderson, Narci C. Teoh, Christopher J. Nolan, Auvro R. Mridha, Fahrettin Haczeyni, Emma Estevez, Geoffrey C. Farrell
Publikováno v:
Obesity. 23:1845-1855
Objective Adipose inflammation and dysfunction underlie metabolic obesity. Exercise improves glycemic control and metabolic indices, but effects on adipose function and inflammation are less clear. Accordingly, it was hypothesized that exercise impro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::134800ef2cff01901660c1640d0e2845
https://doi.org/10.1002/oby.21170
https://doi.org/10.1002/oby.21170
Autor:
Fahrettin, Haczeyni, Matthew M, Yeh, George N, Ioannou, Isabelle A, Leclercq, Robert, Goldin, Yock Young, Dan, Jun, Yu, Narcissus C, Teoh, Geoffrey C, Farrell
Publikováno v:
Journal of gastroenterology and hepatology. 33(7)
Non-alcoholic steatohepatitis (NASH) is strongly associated with overnutrition, insulin resistance, and predisposition to type 2 diabetes. To critically analyze the translational significance of currently used animal models of NASH, we reviewed artic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2f81ccaf626e0f32a78627e7feb223c3
https://pubmed.ncbi.nlm.nih.gov/29424123
https://pubmed.ncbi.nlm.nih.gov/29424123
Autor:
Yun-Jung Choi, Narcissus Teoh, Vanessa Barn, Hans Wang, George N. Ioannou, Auvro R. Mridha, W. Geoffrey Haigh, Charles A. McWherter, Fahrettin Haczeyni, Matthew M. Yeh, Geoffrey C. Farrell
Publikováno v:
Hepatology Communications
Lipotoxicity associated with insulin resistance is central to nonalcoholic steatohepatitis (NASH) pathogenesis. To date, only weight loss fully reverses NASH pathology, but mixed peroxisome proliferator-activated receptor-alpha/delta (PPAR-α/δ) ago
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a70cd63260acc60fbe7009d820ae126
https://pubmed.ncbi.nlm.nih.gov/29404484
https://pubmed.ncbi.nlm.nih.gov/29404484