Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Fahmida Sarmin"'
Autor:
Jenny M. Nguyen, Jose R. Conejo-Garcia, Hing C. Wong, Melanie R. Rutkowski, Emily K. Jeng, Amelia J. Tesone, Alfredo Perales-Puchalt, Mee Rie Sheen, Fahmida Sarmin, Steven Fiering, Tom L. Stephen, Julia Tchou, Michael J. Allegrezza, Nikolaos Svoronos
Publikováno v:
Cancer Research. 76:2561-2572
Many signal transduction inhibitors are being developed for cancer therapy target pathways that are also important for the proper function of antitumor lymphocytes, possibly weakening their therapeutic effects. Here we show that most inhibitors targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb42ed1ab158fa24d030f743f9eaec4
https://doi.org/10.1158/0008-5472.can-15-2808
https://doi.org/10.1158/0008-5472.can-15-2808
Autor:
Melanie Rutkowski, Ximena Escovar-Fadul, Fahmida Sarmin, Tom Stephen, Michael Allegrezza, Oswaldo Gil-Guerva, Amelia Tesone, Jose Conejo-Garcia
Publikováno v:
The Journal of Immunology. 188:162.48-162.48
It has been reported that up to 25% of the human population carries a dominant point mutation in TLR5 resulting in the loss of TLR5 signaling. TLR5 expression is paramount in modulating the balance of regulatory FoxP3+ and proinflamatory IL-17+ T cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b3b27d8c29ebf90c3fc0df8d96bf939
https://doi.org/10.4049/jimmunol.188.supp.162.48
https://doi.org/10.4049/jimmunol.188.supp.162.48
Autor:
Julia Tchou, Michael J. Allegrezza, Jose R. Conejo-Garcia, Mark E. Borowsky, Melanie R. Rutkowski, Fahmida Sarmin, Nikolaos Svoronos, Tom L. Stephen, Jenny M. Nguyen, Alfredo Perales-Puchalt, Amelia J. Tesone
Publikováno v:
Immunity. (3):427-439
Summary Tumor-reactive T cells become unresponsive in advanced tumors. Here we have characterized a common mechanism of T cell unresponsiveness in cancer driven by the upregulation of the transcription factor Forkhead box protein P1 (Foxp1), which pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc4a4722bcb3229e6c9ac6209d6abe3