Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Fahire G Akarca"'
Autor:
Hui Zheng, Eirini Pectasides, Mohamed Uduman, Charles S Fuchs, James M Cleary, Adam J Bass, Jérémy Augustin, Leonie K de Klerk, Anuj K Patel, Sarah Derks, Nihal Raman, Fahire G Akarca, Nadine J McCleary, Douglas A Rubinson, Jeffrey W Clark, Bridget Fitzpatrick, Lauren K Brais, Megan E Cavanaugh, Amanda J Rode, Melissa G Jean, Patrick H Lizotte, Matthew J Nazzaro, Peter C Enzinger
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 9 (2021)
Externí odkaz:
https://doaj.org/article/88b5dffda1124385a9d172a7073bce20
Autor:
Adam J. Bass, Channing J. Der, Douglas R. Lowy, Adrienne D. Cox, Emanuel F. Petricoin, Kwok-Kin Wong, George Church, Timothy C. Wang, Katherine A. Hoadley, Mariaelena Pierobon, Sarah Derks, Leonie K. de Klerk, Fahire G. Akarca, Zhong Wu, Jin Zhou, Jennifer Liao, Matthew D. Stachler, Alex G. Papageorge, J. Nathaniel Diehl, Devon R. Blake, Richard G. Hodge, Yichen Wang, Antje Schaefer, Haisheng Zhang
Supplementary Figures and Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e810e7c390d32bad4be2d052c43dbf2
https://doi.org/10.1158/2159-8290.22535581.v1
https://doi.org/10.1158/2159-8290.22535581.v1
Autor:
Adam J. Bass, Channing J. Der, Douglas R. Lowy, Adrienne D. Cox, Emanuel F. Petricoin, Kwok-Kin Wong, George Church, Timothy C. Wang, Katherine A. Hoadley, Mariaelena Pierobon, Sarah Derks, Leonie K. de Klerk, Fahire G. Akarca, Zhong Wu, Jin Zhou, Jennifer Liao, Matthew D. Stachler, Alex G. Papageorge, J. Nathaniel Diehl, Devon R. Blake, Richard G. Hodge, Yichen Wang, Antje Schaefer, Haisheng Zhang
Diffuse gastric cancer (DGC) is a lethal malignancy lacking effective systemic therapy. Among the most provocative recent results in DGC has been that of highly recurrent missense mutations in the GTPase RHOA. The function of these mutations has rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a2062b37221a584c9e0557e87fe2a8e
https://doi.org/10.1158/2159-8290.c.6547882.v1
https://doi.org/10.1158/2159-8290.c.6547882.v1
Autor:
Adam J. Bass, Channing J. Der, Douglas R. Lowy, Adrienne D. Cox, Emanuel F. Petricoin, Kwok-Kin Wong, George Church, Timothy C. Wang, Katherine A. Hoadley, Mariaelena Pierobon, Sarah Derks, Leonie K. de Klerk, Fahire G. Akarca, Zhong Wu, Jin Zhou, Jennifer Liao, Matthew D. Stachler, Alex G. Papageorge, J. Nathaniel Diehl, Devon R. Blake, Richard G. Hodge, Yichen Wang, Antje Schaefer, Haisheng Zhang
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32cf2b19817995da9a9a75ad73aa191b
https://doi.org/10.1158/2159-8290.22535578
https://doi.org/10.1158/2159-8290.22535578
Autor:
Adam J. Bass, Channing J. Der, Douglas R. Lowy, Adrienne D. Cox, Emanuel F. Petricoin, Kwok-Kin Wong, George Church, Timothy C. Wang, Katherine A. Hoadley, Mariaelena Pierobon, Sarah Derks, Leonie K. de Klerk, Fahire G. Akarca, Zhong Wu, Jin Zhou, Jennifer Liao, Matthew D. Stachler, Alex G. Papageorge, J. Nathaniel Diehl, Devon R. Blake, Richard G. Hodge, Yichen Wang, Antje Schaefer, Haisheng Zhang
List of Models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a32eefeff46aef947cd43c914935d6ac
https://doi.org/10.1158/2159-8290.22535575
https://doi.org/10.1158/2159-8290.22535575
Autor:
Adam J. Bass, Channing J. Der, Douglas R. Lowy, Adrienne D. Cox, Emanuel F. Petricoin, Kwok-Kin Wong, George Church, Timothy C. Wang, Katherine A. Hoadley, Mariaelena Pierobon, Sarah Derks, Leonie K. de Klerk, Fahire G. Akarca, Zhong Wu, Jin Zhou, Jennifer Liao, Matthew D. Stachler, Alex G. Papageorge, J. Nathaniel Diehl, Devon R. Blake, Richard G. Hodge, Yichen Wang, Antje Schaefer, Haisheng Zhang
Supplementary Video S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::593f9baaa0b2cdf971f6b99af39b1142
https://doi.org/10.1158/2159-8290.22535554.v1
https://doi.org/10.1158/2159-8290.22535554.v1
Autor:
Eirini Pectasides, Sarah Derks, Charles S. Fuchs, Megan E. Cavanaugh, Peter C. Enzinger, Anuj K. Patel, Amanda J. Rode, Douglas A. Rubinson, Adam J. Bass, Bridget Fitzpatrick, Lauren K. Brais, Nadine Jackson McCleary, Mariano Severgnini, Patrick H. Lizotte, Fahire G Akarca, Jeffrey W. Clark, Leonie K. de Klerk, Melissa G Jean, Matthew Nazzaro, Jeremy Augustin, Mohamed Uduman, James M. Cleary, Hui Zheng, Nihal Raman
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 9 (2021)
Journal for Immunotherapy of Cancer, 9(9):e002472. BioMed Central
de Klerk, L K, Patel, A K, Derks, S, Pectasides, E, Augustin, J, Uduman, M, Raman, N, Akarca, F G, McCleary, N J, Cleary, J M, Rubinson, D A, Clark, J W, Fitzpatrick, B, Brais, L K, Cavanaugh, M E, Rode, A J, Jean, M G, Lizotte, P H, Nazzaro, M J, Severgnini, M, Zheng, H, Fuchs, C S, Enzinger, P C & Bass, A J 2021, ' Phase II study of pembrolizumab in refractory esophageal cancer with correlates of response and survival ', Journal for Immunotherapy of Cancer, vol. 9, no. 9, e002472 . https://doi.org/10.1136/jitc-2021-002472, https://doi.org/10.1136/jitc-2021-002472
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer, 9(9):e002472. BioMed Central
de Klerk, L K, Patel, A K, Derks, S, Pectasides, E, Augustin, J, Uduman, M, Raman, N, Akarca, F G, McCleary, N J, Cleary, J M, Rubinson, D A, Clark, J W, Fitzpatrick, B, Brais, L K, Cavanaugh, M E, Rode, A J, Jean, M G, Lizotte, P H, Nazzaro, M J, Severgnini, M, Zheng, H, Fuchs, C S, Enzinger, P C & Bass, A J 2021, ' Phase II study of pembrolizumab in refractory esophageal cancer with correlates of response and survival ', Journal for Immunotherapy of Cancer, vol. 9, no. 9, e002472 . https://doi.org/10.1136/jitc-2021-002472, https://doi.org/10.1136/jitc-2021-002472
Journal for Immunotherapy of Cancer
BackgroundImmune checkpoint inhibitors have revolutionized cancer treatment, but the benefits in refractory patients with esophageal cancer have been modest. Predictors of response as well as new targets for novel therapeutic combinations are needed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c810cbc651fe7a89668ba3764f6711a
https://jitc.bmj.com/content/9/9/e002472.full
https://jitc.bmj.com/content/9/9/e002472.full
Autor:
Diane Stapleton, Mark Redston, Fahire G Akarca, Matthew D. Stachler, Richard H. Lash, Marianne Rara, Laurel Nowden, Anthony Kim, Amy Noffsinger, Adam J. Bass
Publikováno v:
Gastroenterology. 162(2)
BACKGROUND AND AIMS Barrett's esophagus (BE) is the precursor to esophageal adenocarcinoma. A major challenge is identifying the small group with BE who will progress to advanced disease from the many who will not. Assessment of p53 status has promis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83ed38df23bef6698f8c97c35e17df56
https://pubmed.ncbi.nlm.nih.gov/34757142
https://pubmed.ncbi.nlm.nih.gov/34757142
Autor:
Mark Redston, Adam J. Bass, Diane Stapleton, Fahire G Akarca, Anthony Kim, Laurel Nowden, Matthew D. Stachler, Richard H. Lash, Amy Noffsinger
Barrett’s esophagus is the precursor to esophageal adenocarcinomas, which are deadly cancers with a rapidly rising incidence. A major challenge is identifying the small group with Barrett’s esophagus who will progress to advanced disease from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b382c75d8d101c5d061295a39c8aa73
https://doi.org/10.1101/2020.10.18.20213561
https://doi.org/10.1101/2020.10.18.20213561
Autor:
Ben Li, S. Derks, Felix Dietlein, Fahire G Akarca, X. Xu, A.C. Da Silva, L.K. de Klerk, E.M. Van Allen, Scott J. Rodig, Shirley Liu, Anna Maria Chiaravalli, Gordon J. Freeman, Jason L. Hornick, Kevin X. Liu, Adam J. Bass, T. Fleitas, Claire A. Margolis, Vesteinn Thorsson, Yang Liu, Shuji Ogino
Publikováno v:
Ann Oncol
Annals of Oncology, 31(8), 1011-1020. Oxford University Press
Derks, S, de Klerk, L K, Xu, X, Fleitas, T, Liu, K X, Liu, Y, Dietlein, F, Margolis, C, Chiaravalli, A M, Da Silva, A C, Ogino, S, Akarca, F G, Freeman, G J, Rodig, S J, Hornick, J L, van Allen, E, Li, B, Liu, S X, Thorsson, V & Bass, A J 2020, ' Characterizing diversity in the tumor-immune microenvironment of distinct subclasses of gastroesophageal adenocarcinomas ', Annals of Oncology, vol. 31, no. 8, pp. 1011-1020 . https://doi.org/10.1016/j.annonc.2020.04.011
Annals of Oncology, 31(8), 1011-1020. Oxford University Press
Derks, S, de Klerk, L K, Xu, X, Fleitas, T, Liu, K X, Liu, Y, Dietlein, F, Margolis, C, Chiaravalli, A M, Da Silva, A C, Ogino, S, Akarca, F G, Freeman, G J, Rodig, S J, Hornick, J L, van Allen, E, Li, B, Liu, S X, Thorsson, V & Bass, A J 2020, ' Characterizing diversity in the tumor-immune microenvironment of distinct subclasses of gastroesophageal adenocarcinomas ', Annals of Oncology, vol. 31, no. 8, pp. 1011-1020 . https://doi.org/10.1016/j.annonc.2020.04.011
Background Gastroesophageal adenocarcinomas (GEAs) are heterogeneous cancers where immune checkpoint inhibitors have robust efficacy in heavily inflamed microsatellite instability (MSI) or Epstein-Barr virus (EBV)-positive subtypes. Immune checkpoint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac081e16c2b5abccbd9a9efc5d5e6879
https://europepmc.org/articles/PMC7690253/
https://europepmc.org/articles/PMC7690253/