Výsledky vyhledávání - "Fahd Benjelloun"

Akademický článek

Activation of Toll-Like Receptors Differentially Modulates Inflammation in the Human Reproductive Tract: Preliminary Findings

Autor: Fahd Benjelloun, Héloïse Quillay, Claude Cannou, Romain Marlin, Yoann Madec, Hervé Fernandez, Fabrice Chrétien, Roger Le Grand, Françoise Barré-Sinoussi, Marie-Thérèse Nugeyre, Elisabeth Menu

Publikováno v: Frontiers in Immunology, Vol 11 (2020)

The female reproductive tract (FRT) is the main site of entry of sexually transmitted infections (STIs). Toll-like receptors (TLRs) that recognize pathogenic motifs are widely expressed in the FRT. TLR stimulation induces immune activation and local

Externí odkaz: https://doaj.org/article/6859f61e6e5c42469b48390664afe1d4

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Akademický článek

Dynamics of Vaginal and Rectal Microbiota Over Several Menstrual Cycles in Female Cynomolgus Macaques

Autor: Marie-Thérèse Nugeyre, Nicolas Tchitchek, Cindy Adapen, Claude Cannou, Vanessa Contreras, Fahd Benjelloun, Jacques Ravel, Roger Le Grand, Romain Marlin, Elisabeth Menu

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)

The composition of the microbiota in cynomolgus macaques is only partially characterized, although this animal model is often used to study pathogenesis and preventive strategies against infections. We thus performed, for the first time, a longitudin

Externí odkaz: https://doaj.org/article/eedee43244944307a81868dabb92dc47

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Akademický článek

Seminal Plasma Exposures Strengthen Vaccine Responses in the Female Reproductive Tract Mucosae

Autor: Romain Marlin, Marie-Thérèse Nugeyre, Nicolas Tchitchek, Matteo Parenti, Cécile Lefebvre, Hakim Hocini, Fahd Benjelloun, Claude Cannou, Silvia Nozza, Nathalie Dereuddre-Bosquet, Yves Levy, Françoise Barré-Sinoussi, Gabriella Scarlatti, Roger Le Grand, Elisabeth Menu

Publikováno v: Frontiers in Immunology, Vol 10 (2019)

HIV-1 sexual transmission occurs mainly via mucosal semen exposures. In the female reproductive tract (FRT), seminal plasma (SP) induces physiological modifications, including inflammation. An effective HIV-1 vaccine should elicit mucosal immunity, h

Externí odkaz: https://doaj.org/article/9be9253e678345728e99c5e3f12e2168

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A high mucosal blocking score is associated with HIV protection

Autor: Mario Clerici, Bernard Verrier, Norma Rallón, Blandine Chanut, Jorge del Romero, Alexandre Girard, Christian Genin, Stéphane Paul, Mara Biasin, Frédéric Lucht, Fabienne Jospin, José M. Benito, Jean Jacques Pin, Fahd Benjelloun, Carmen Rodríguez

Publikováno v: AIDS
AIDS, Lippincott, Williams & Wilkins, 2019, 33 (3), pp.411-423. ⟨10.1097/QAD.0000000000002099⟩
AIDS. Official journal of the international AIDS Society
AIDS. Official journal of the international AIDS Society, 2019, 33 (3), pp.411-423. ⟨10.1097/QAD.0000000000002099⟩

International audience; BACKGROUND:Early steps of HIV infection are mediated by the binding of the envelope to mucosal receptors as α4β7 and the C-type lectins DC-SIGN and langerin. Previously Env-specific B-cell responses have been reported in hig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e526359b0fc46cf5230fb418fcd34f
https://hal.archives-ouvertes.fr/hal-02351387

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Modified Vaccinia Virus Ankara Vector Induces Specific Cellular and Humoral Responses in the Female Reproductive Tract, the Main HIV Portal of Entry

Autor: Elisabeth Menu, Nathalie Dereuddre-Bosquet, Claude Cannou, Roger Le Grand, Matteo Parenti, Hakim Hocini, Marie-Thérèse Nugeyre, Françoise Barré-Sinoussi, Romain Marlin, Nicolas Tchitchek, Fahd Benjelloun, Yves Levy, Gabriella Scarlatti

Publikováno v: Journal of Immunology
Journal of Immunology, 2017, 199 (5), pp.1923-1932. ⟨10.4049/jimmunol.1700320⟩

The female reproductive tract (FRT) is one of the major mucosal invasion sites for HIV-1. This site has been neglected in previous HIV-1 vaccine studies. Immune responses in the FRT after systemic vaccination remain to be characterized. Using a modif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3981bb566f509e3041cd534885631db
https://hal-pasteur.archives-ouvertes.fr/pasteur-01597708/document

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First Membrane Proximal External Region-Specific Anti-HIV1 Broadly Neutralizing Monoclonal IgA1 Presenting Short CDRH3 and Low Somatic Mutations

Autor: Alexandre Girard, Fabienne Jospin, Christian Genin, Gaël Champier, Bernard Verrier, Stéphane Paul, Michel Cogné, Nicole M. Thielens, Blandine Chanut, Nicolas Rochereau, Zeliha Oruc, Nadine Vincent, Fahd Benjelloun

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2016, 197 (5), pp.1979-88. ⟨10.4049/jimmunol.1600309⟩
Journal of Immunology, 2016, 197 (5), pp.1979-88. ⟨10.4049/jimmunol.1600309⟩

Mucosal HIV-1–specific IgA have been described as being able to neutralize HIV-1 and to block viral transcytosis. In serum and saliva, the anti-HIV IgA response is predominantly raised against the envelope of HIV-1. In this work, we describe the in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::773ccb264a8e608a82534ead3dcb0577
https://hal.univ-grenoble-alpes.fr/hal-01356638

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The local environment orchestrates mucosal decidual macrophage differentiation and substantially inhibits HIV-1 replication

Autor: Héloïse Quillay, H. El Costa, Marion Duriez, J Ighil, Romain Marlin, Françoise Barré-Sinoussi, Fahd Benjelloun, C. de Truchis, Elisabeth Menu, Claude Cannou, M. Rahmati, Marie-Thérèse Nugeyre

Publikováno v: Mucosal Immunology
Mucosal Immunology, Nature Pub. Group, 2016, 9 (3), pp.634-46. ⟨10.1038/mi.2015.87⟩
Mucosal Immunology, 2016, 9 (3), pp.634-46. ⟨10.1038/mi.2015.87⟩

International audience; Macrophages from the decidua basalis (dM), the main uterine mucosa during pregnancy, are weakly permissive to HIV-1 infection. Here, we investigated the mechanisms underlying this natural control. We show, by using freshly pur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::764efd7d7f7fb011bb2f2f76d831e437
https://hal-pasteur.archives-ouvertes.fr/pasteur-01453433

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Role of human immunodeficiency virus type 1 envelope structure in the induction of broadly neutralizing antibodies

Autor: Christian Genin, Bernard Verrier, P. Lawrence, Stéphane Paul, Fahd Benjelloun

Publikováno v: Journal of virology. 86(24)

Very soon after the discovery of neutralizing antibodies (NAbs) toward human immunodeficiency virus type 1 (HIV-1) infection, it became apparent that characterization of these NAbs would be an important step in finding a cure for or a vaccine to erad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8edf092f3060d0ac74bfff3821cf342
https://pubmed.ncbi.nlm.nih.gov/23015715

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HIV-1 Glycoprotein Immunogenicity

Autor: Stéphane Paul, Fahd Benjelloun, Christian Genin

Publikováno v: Recent Translational Research in HIV/AIDS

The Human Immunodeficiency Virus type 1 (HIV-1) is a C-type enveloped retrovirus (classification based on morphology of retroviruses electron microscopy) of the Retroviridae family. It’s consisting in a genome of 2 positive stranded RNA molecules a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a89a2d133742a38e621f3f69e8511583
https://doi.org/10.5772/23209

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Promyelocytic leukemia-nuclear body formation is an early event leading to retinoic acid-induced differentiation of neuroblastoma cells

Autor: Camille Ripoll, Fahd Benjelloun, A. Delaune, E. Legrand, Cécile Corbière, Vannier Jp, Marc Vasse

Publikováno v: Journal of Neurochemistry
Journal of Neurochemistry, Wiley, 2007, 104 (1), pp.071106220615005-???. ⟨10.1111/j.1471-4159.2007.05019.x⟩

International audience; Neuroblastoma is one of the most common cancers in children. Neuroblastoma differentiation is linked to the presence of the promyelocytic leukemia (PML) protein. Retinoic acid, a powerful differentiation-inducer in vitro, is a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73efc1cf68448f512797eb69f8c4245e
https://doi.org/10.1111/j.1471-4159.2007.05019.x

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