Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Fahad Benthani"'
Autor:
Nicola Currey, Zeenat Jahan, C. Elizabeth Caldon, Phuong N. Tran, Fahad Benthani, Penelope De Lacavalerie, Daniel L. Roden, Brian S. Gloss, Claudia Campos, Elaine G. Bean, Amanda Bullman, Saskia Reibe-Pal, Marcel E. Dinger, Mark A. Febbraio, Stephen J. Clarke, Jane E. Dahlstrom, Maija R.J. Kohonen-Corish
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 4, Pp 819-839 (2019)
Background & Aims: The early events by which inflammation promotes cancer are still not fully defined. The MCC gene is silenced by promoter methylation in colitis-associated and sporadic colon tumors, but its functional significance in precancerous l
Externí odkaz:
https://doaj.org/article/3f5a2d0c39a64c9b94fae8baddfca8d1
Autor:
Dessislava N. Mladenova, Jane E. Dahlstrom, Phuong N. Tran, Fahad Benthani, Elaine G. Bean, Irvin Ng, Laurent Pangon, Nicola Currey, Maija R. J. Kohonen-Corish
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 9, Pp 1093-1103 (2015)
Hypoxia-inducible factor 1α (HIF1α) is a transcription factor that regulates the adaptation of cells to hypoxic microenvironments, for example inside solid tumours. Stabilisation of HIF1α can also occur in normoxic conditions in inflamed tissue or
Externí odkaz:
https://doaj.org/article/c4eabf5f865941bdb4e7569db2f3fceb
Autor:
Markus Landthaler, Bernd Lamprecht, Riad Ghanem, Amjad Khan, Michael Mülleder, Maurice Reimann, Herta Steinkellner, Soyoung Lee, Emanuel Wyler, Mario Mairhofer, Wolfram Hoetzenecker, Paulina Richter-Pechanska, Séverine Kunz, Josef Tomasits, Rupert Langer, Kristina Dietert, Michael Schotsaert, Maria Pammer, Carles Martínez-Romero, Susanne Kimeswenger, Theresa C. Firsching, Jakob Trimpert, Melissa Uccellini, Achim D. Gruber, Bettina Purfürst, Adolfo García-Sastre, Clemens A. Schmitt, Reinhard Motz, Nikolaus Osterrieder, Anna Habringer, Markus Ralser, Julia Adler, Fahad Benthani, Martin Schönlein, Andrea Lau, Daniela Niemeyer, Christian Drosten, Dimitri Belenki, Dorothy N. Y. Fan, Roland Eils, Francesco Di Pierro, Lea Kausche, Gagandeep Singh, Christian Paar, Edward Georg Michaelis, Helmut J. F. Salzer, Yong Yu, Sabine Kaltenbrunner
Publikováno v:
Nature. 599(7884)
Derailed cytokine and immune cell networks account for the organ damage and the clinical severity of COVID-19 (refs. 1–4). Here we show that SARS-CoV-2, like other viruses, evokes cellular senescence as a primary stress response in infected cells.
Autor:
Saskia Reibe-Pal, Mark A. Febbraio, Amanda Bullman, Brian S. Gloss, Elaine G. Bean, C. Elizabeth Caldon, Stephen Clarke, Marcel E. Dinger, Nicola Currey, Daniel L. Roden, Maija R.J. Kohonen-Corish, Phuong N. Tran, Penelope De Lacavalerie, Fahad Benthani, Jane E. Dahlstrom, Claudia Guimarães Camargo Campos, Zeenat Jahan
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 4, Pp 819-839 (2019)
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 4, Pp 819-839 (2019)
Background & Aims The early events by which inflammation promotes cancer are still not fully defined. The MCC gene is silenced by promoter methylation in colitis-associated and sporadic colon tumors, but its functional significance in precancerous le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c468af758b15860c11906bdd37df6fef
Autor:
Amr H. Allam, Maija R.J. Kohonen-Corish, Fahad Benthani, Paul Timpson, Nicola Currey, Sam Al-Sohaily, T. Phuong, Janindra Warusavitarne, Morghan C. Lucas, David Herrmann
Publikováno v:
ESMO Open. 3:A86-A87
Introduction The ‘Mutated in colorectal cancer’ (MCC) gene was originally discovered due to its linkage with the APC gene. MCC is silenced through gene promoter methylation in colorectal cancer (CRC) but its significance has been poorly understoo
Autor:
Phuong N. Tran, Louise Carey, Fahad Benthani, Marc Giry-Laterriere, Laurent Pangon, Irvin Ng, Maija R.J. Kohonen-Corish, Nicola Currey
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 16, Iss 5, Pp 11522-11530 (2015)
International Journal of Molecular Sciences, Vol 16, Iss 5, Pp 11522-11530 (2015)
Mutations of the SHANK3 gene have been associated with autism spectrum disorder. Individuals harboring different SHANK3 mutations display considerable heterogeneity in their cognitive impairment, likely due to the high SHANK3 transcriptional diversit