Zobrazeno 1 - 10
of 1 269
pro vyhledávání: '"Fagerberg P"'
Autor:
Pal, Adittya, Fagerberg, Rolf, Andersen, Jakob Lykke, Flamm, Christoph, Dittrich, Peter, Merkle, Daniel
Finding pathways that optimize the formation of a particular target molecule in a chemical reaction network is a key problem in many settings, including reactor systems. Reaction networks are mathematically well represented as hypergraphs, a modeling
Externí odkaz:
http://arxiv.org/abs/2411.15900
We propose a seasonal AR model with time-varying parameter processes in both the regular and seasonal parameters. The model is parameterized to guarantee stability at every time point and can accommodate multiple seasonal periods. The time evolution
Externí odkaz:
http://arxiv.org/abs/2409.18640
Autor:
Andersen, Jakob L., Davoodi, Akbar, Fagerberg, Rolf, Flamm, Christoph, Fontana, Walter, Kolčák, Juri, Laurent, Christophe V. F. P., Merkle, Daniel, Nøjgaard, Nikolai
The explosion of data available in life sciences is fueling an increasing demand for expressive models and computational methods. Graph transformation is a model for dynamic systems with a large variety of applications. We introduce a novel method of
Externí odkaz:
http://arxiv.org/abs/2404.02692
Autor:
Andersen, Jakob L., Banke, Sissel, Fagerberg, Rolf, Flamm, Christoph, Merkle, Daniel, Stadler, Peter F.
The exploration of pathways and alternative pathways that have a specific function is of interest in numerous chemical contexts. A framework for specifying and searching for pathways has previously been developed, but a focus on which of the many pat
Externí odkaz:
http://arxiv.org/abs/2309.10629
Information on the structure of molecules, retrieved via biochemical databases, plays a pivotal role in various disciplines, such as metabolomics, systems biology, and drug discovery. However, no such database can be complete, and the chemical struct
Externí odkaz:
http://arxiv.org/abs/2308.12735
Autor:
Tieu-Long Phan, Klaus Weinbauer, Thomas Gärtner, Daniel Merkle, Jakob L. Andersen, Rolf Fagerberg, Peter F. Stadler
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-18 (2024)
Abstract Purpose Reaction databases are a key resource for a wide variety of applications in computational chemistry and biochemistry, including Computer-aided Synthesis Planning (CASP) and the large-scale analysis of metabolic networks. The full pot
Externí odkaz:
https://doaj.org/article/b648281f42a7453a94f4907c86e00bba
Autor:
Andrea Accogli, Saurabh Shakya, Taewoo Yang, Christine Insinna, Soo Yeon Kim, David Bell, Kirill R. Butov, Mariasavina Severino, Marcello Niceta, Marcello Scala, Hyun Sik Lee, Taekyeong Yoo, Jimmy Stauffer, Huijie Zhao, Chiara Fiorillo, Marina Pedemonte, Maria C. Diana, Simona Baldassari, Viktoria Zakharova, Anna Shcherbina, Yulia Rodina, Christina Fagerberg, Laura Sønderberg Roos, Jolanta Wierzba, Artur Dobosz, Amanda Gerard, Lorraine Potocki, Jill A. Rosenfeld, Seema R. Lalani, Tiana M. Scott, Daryl Scott, Mahshid S. Azamian, Raymond Louie, Hannah W. Moore, Neena L. Champaigne, Grace Hollingsworth, Annalaura Torella, Vincenzo Nigro, Rafal Ploski, Vincenzo Salpietro, Federico Zara, Simone Pizzi, Giovanni Chillemi, Marzia Ognibene, Erin Cooney, Jenny Do, Anders Linnemann, Martin J. Larsen, Suzanne Specht, Kylie J. Walters, Hee-Jung Choi, Murim Choi, Marco Tartaglia, Phillippe Youkharibache, Jong-Hee Chae, Valeria Capra, Sung-Gyoo Park, Christopher J. Westlake
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract WDR44 prevents ciliogenesis initiation by regulating RAB11-dependent vesicle trafficking. Here, we describe male patients with missense and nonsense variants within the WD40 repeats (WDR) of WDR44, an X-linked gene product, who display cilio
Externí odkaz:
https://doaj.org/article/af57c8de8d9140e89c63f41fb89329f6
Autor:
Andersen, Jakob L., Fagerberg, Rolf, Flamm, Christoph, Fontana, Walter, Kolčák, Juri, Laurent, Christophe V. F. P., Merkle, Daniel, Nøjgaard, Nikolai
Reaction mechanisms are often presented as sequences of elementary steps, such as codified by arrow pushing. We propose an approach for representing such mechanisms using graph transformation. In this framework, each elementary step is a rule for mod
Externí odkaz:
http://arxiv.org/abs/2201.04515
Autor:
Andersen, Jakob L., Fagerberg, Rolf, Kolčák, Juri, Laurent, Christophe V. F. P., Merkle, Daniel, Nøjgaard, Nikolai
Graph transformation formalisms have proven to be suitable tools for the modelling of chemical reactions. They are well established in theoretical studies and increasingly also in practical applications in chemistry. The latter is made feasible via t
Externí odkaz:
http://arxiv.org/abs/2201.04360
Autor:
Ditte Buchwald, Casper Schmidt, Dorte Buchwald, Kristina Iris Winter, Ivan Bo Nielsen, Kirsten Klostergaard, Dorte Melgaard, Steen K. Fagerberg, Peter Derek Christian Leutscher
Publikováno v:
Palliative Medicine Reports, Vol 4, Iss 1, Pp 326-333 (2023)
Background: Cannabis may offer therapeutic benefits to patients with advanced cancer not responding adequately to conventional palliative treatment. However, tolerability is a major concern. Cognitive function is a potential adverse reaction to tetra
Externí odkaz:
https://doaj.org/article/72e3bb9b72524ce48ef48d6138227e21