Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Fafa Baouchi-Mokrane"'
Autor:
Fafa Baouchi-Mokrane, Gregory T. Everson, James R. Burton, Liviawati Sutjandra Wu, Jennifer J. Kiser, Thomas J. Urban, David Z. D'Argenio, Peter L. Anderson, Joseph E. Rower, Kyle P. Hammond
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:2179-2188
Ribavirin, a guanosine analog, is a broad-spectrum antiviral agent. Ribavirin has been a fundamental component of the treatment of hepatitis C virus (HCV) infection for decades, but there is a very limited understanding of the clinical pharmacology o
Autor:
Jacob A. Langness, Zayani Sims, Jennifer J. Kiser, Eric G. Meissner, Aimee E. Truesdale, Leah C. Jimmerson, Thomas J. Urban, Christina L. Aquilante, Fafa Baouchi-Mokrane, Shyam Kottilil, Ariel Hodara
Publikováno v:
Journal of clinical pharmacology. 57(1)
Individuals with lower inosine triphosphatase (ITPA) enzyme activity have a reduced likelihood of experiencing hemolytic anemia during hepatitis C virus (HCV) treatment containing ribavirin (RBV). Because ITPA degrades purines and RBV is a purine ana