Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Faezeh Borzooee"'
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
APOBEC3G (A3G) is a host enzyme that mutates the genomes of retroviruses like HIV. Since A3G is expressed pre-infection, it has classically been considered an agent of innate immunity. We and others previously showed that the impact of A3G-induced mu
Externí odkaz:
https://doaj.org/article/a62c3e9fce5144838e1eb28e3d4d3bb0
Publikováno v:
Iranian Journal of Microbiology, Vol 5, Iss 2 (2013)
Background and Objectives: Sodium dodecyl sulfate (SDS) is one of the main surfactant components in detergents and cosmetics, used in high amounts as a detergent in products such as shampoos, car wash soap and toothpaste. Therefore, its bioremediatio
Externí odkaz:
https://doaj.org/article/b39d1eb746c243829c56d8e44c4fca9d
Autor:
Sarah Grasedieck, Afsaneh Panahi, Matthew C. Jarvis, Faezeh Borzooee, Reuben S. Harris, Mani Larijani, Hervé Avet-Loiseau, Mehmet Samur, Nikhil Munshi, Kevin Song, Arefeh Rouhi, Florian Kuchenbauer
Background: Recent insights into the pathogenesis of multiple myeloma (MM) have highlighted inflammation and genome editing, e.g. by APOBEC enzymes, as major drivers of disease onset and progression. We hypothesized that inclusion of molecular featur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f37948463e8a67b7dbb561ff5cd4d1ab
https://doi.org/10.21203/rs.3.rs-2184702/v1
https://doi.org/10.21203/rs.3.rs-2184702/v1
Autor:
Afsaneh Panahi, Sarah Grasedieck, Matthew Jarvis, Faezeh Borzooee, Reuben Harris, Mani Larijani, Kevin Song, Arefeh Rouhi, Florian Kuchenbauer
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 22:S117-S118
Autor:
Mani Larijani, Faezeh Borzooee
Publikováno v:
New Biotechnology. 51:67-79
AID/APOBEC3 enzymes are cytidine deaminases that mutate antibody and retroviral genes and also mediate extensive tumor genome mutagenesis. The study of purified AID/APOBEC3 proteins is challenged by difficulties with their expression and purification
Autor:
Cody P. Diamond, Faezeh Borzooee, Justin J King, Mani Larijani, Mahdi Asgharpour, Heather Fifield, Atefeh Ghorbani, Lesley M. Berghuis, Junbum Im
Publikováno v:
ACS pharmacologytranslational science. 4(4)
Activation-induced cytidine deaminase (AID) initiates antibody diversification by mutating immunoglobulin loci in B lymphocytes. AID and related APOBEC3 (A3) enzymes also induce genome-wide mutations and lesions implicated in tumorigenesis and tumor
Autor:
Matthew C. Jarvis, Reuben S. Harris, Sarah Grasedieck, Faezeh Borzooee, Arefeh Rouhi, Florian Kuchenbauer, Kevin W. Song, Mani Larijani, Afsaneh M. Shariatpanahi
Publikováno v:
Blood. 138:4718-4718
Background: The prognosis of MM is determined by affected organs, tumor burden as measured by e.g., the international staging system (ISS), disease biology such as cytogenetic abnormalities, and response to therapy. The outcome of high-risk MM patien
Autor:
Florian Kuchenbauer, Mani Larijani, Arefeh Rouhi, Matthew C. Jarvis, Kevin W. Song, Reuben S. Harris, Faezeh Borzooee, Afsaneh M. Shariatpanahi, Sarah Grasedieck
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 21:S100
Background Current clinical prognostication of newly diagnosed MM (NDMM) patients relies on clinical parameters and/or recurrent genetic changes, which mainly reflect early events in the development of MM. However, recent insights into the pathogenes
Publikováno v:
International Reviews of Immunology. 37:151-164
APOBEC3s (A3) are endogenous DNA-editing enzymes that are expressed in immune cells including T lymphocytes. A3s target and mutate the genomes of retroviruses that infect immune tissues such as the human immunodeficiency virus (HIV). Therefore, A3s w
Autor:
Faezeh Borzooee
Publikováno v:
Cancer Research. 81:1483-1483
Background: Tumor antigens (TA) on cancer cells can trigger immune response TA are peptides that are either not present, or are present to a much lesser extent, on normal cells compared to tumor cells. CD8+ Cytotoxic T-cells (CTL) recognize TAs bound