Chemoselective and diastereodivergent synthesis of new spirooxindolo-pyrrolizidines and pyrrolidines stemming from unsymmetrical 1,3-bis(arylidene)tetral-2-ones: a combined experimental and theoretical study

Autor: Houda Gazzeh, Fadwa Rouatbi, Sami Chniti, Moheddine Askri, Michael Knorr, Carsten Strohmann, Christopher Golz, Al Mokhtar Lamsabhi

Publikováno v: New Journal of Chemistry. 46:19198-19212

An experimental and theoretical study of an efficient one-pot three-components cycloaddition reaction leading to pentacyclic dispiropyrrolizidin/pyrrolidinoxindoles endowed by four contiguous stereogenic centres with moderate to good yields was repor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9ba076d6fc19492197ba31bb7ff361da
https://doi.org/10.1039/d2nj03887k

Synthesis of new spirooxindole derivatives through 1,3-dipolar cycloaddition of azomethine ylides and their antitubercular activity

Autor: Dharmarajan Sriram, Frederic Nana, Gilbert Kirsch, Moheddine Askri, Fadwa Rouatbi, Perumal Yogeeswari

Publikováno v: Tetrahedron Letters. 57:163-167

Non-stabilized azomethine ylides, generated in situ from isatin derivatives and l -proline, have been reacted with (E,E)-1,3-bis(arylidene)indan-2-ones as dipolarophiles in a 1,3-dipolar cycloaddition reaction. Novel functionalized dispiroheterocycli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9716379645d8d637cc4de260fb09abc4
https://doi.org/10.1016/j.tetlet.2015.11.056

Synthesis of highly substituted spiropyrrolidines via 1, 3-dipolar cycloaddition reaction of N-metalated azomethine ylides. A new access to spiropyrroline derivatives

Autor: Chourouk Mhiri, Fadwa Rouatbi, Sarra Boudriga, Moheddine Askri, Kabula Ciamal, Michael Knorr, Karin Monnier-Jobé, Abderrahim Khatyr, Yoann Rousselin, Marek M. Kubicki

Publikováno v: Mediterranean Journal of Chemistry
Mediterranean Journal of Chemistry, Mediterranean Journal of Chemistry, 2015, 4 (1), pp.30-50
Mediterranean Journal of Chemistry, Vol 4, Iss 1, Pp 30-50 (2015)

1,3-dipolar cycloaddition of (E)-arylidene-(2H)-indanones 1 (Ar = Ph, p-MeC6H4, p-MeOC6H4, p-ClC6H4) and (E)-2-arylidene-(2H)-tetralones 2 (Ar = Ph, p-MeC6H4, p-MeOC6H4, p-ClC6H4) to N-metalated azomethine ylides 3 generated from methyl N-arylidenegl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9648084d5957cae9860f10f44bb485da
https://hal.science/hal-01277418