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pro vyhledávání: '"Fadumo Ahmed Isse"'
Autor:
Sherif Hanafy Mahmoud, Fatma Hefny, Fadumo Ahmed Isse, Shahmeer Farooq, Spencer Ling, Cian O'Kelly, Demetrios James Kutsogiannis
Publikováno v:
Frontiers in Neurology, Vol 14 (2024)
BackgroundNimodipine improves outcomes following aneurysmal subarachnoid hemorrhage (aSAH). Guidelines recommend that all patients should receive a fixed-dose nimodipine for 21 days. However, studies reported variability of nimodipine concentrations
Externí odkaz:
https://doaj.org/article/549446bd75524c30abdcdc899943fce0
Publikováno v:
Analytica, Vol 2, Iss 3, Pp 57-65 (2021)
Clobazam (CLB) is a benzodiazepine that is used in many types of epilepsy. Although therapeutic drug monitoring (TDM) of CLB is not routine, there is evidence that TDM may be of value in conditions where pharmacokinetic alterations are suspected. The
Externí odkaz:
https://doaj.org/article/3e02c36425584294b8d2ea62ba7c949b
Publikováno v:
Drugs in R&D, Vol 20, Iss 4, Pp 307-318 (2020)
Abstract Nimodipine has been shown to improve outcomes following aneurysmal subarachnoid hemorrhage. Guidelines recommend that all patients receive a fixed dose of oral nimodipine for 21 days. However, pharmacokinetic studies have suggested variabili
Externí odkaz:
https://doaj.org/article/ed9050c451154a9dba3b5158c9bb7917
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 23, Iss 1 (2020)
PURPOSE: Delayed cerebral ischemia (DCI) and vasospasm are the main challenges contributing to unfavorable outcomes following aneurysmal subarachnoid hemorrhage. Nimodipine has been shown to decrease the incidence of delayed cerebral ischemia and imp
Externí odkaz:
https://doaj.org/article/8e06ca41d9ca4971866c8c6c857ab4aa
Publikováno v:
Prostaglandins & Other Lipid Mediators. 168:106749
Publikováno v:
Drug metabolism reviews.
The incidence of heart failure (HF) is generally preceded by cardiac hypertrophy (CH), which is the enlargement of cardiac myocytes in response to stress. During CH, the metabolism of arachidonic acid (AA), which is present in the cell membrane phosp
Autor:
Fadumo Ahmed Isse, Ahmad H. Alammari, Ahmed A. El-Sherbeni, Dion R. Brocks, Ayman O.S. El-Kadi
Publikováno v:
Prostaglandinsother lipid mediators. 165
Arachidonic acid (AA) is a polyunsaturated fatty acid with a structure of 20:4(ω-6). Cytochrome P450s (CYPs) metabolize AA to several regioisomers and enantiomers of hydroxyeicosatetraenoic acids (HETEs). The hydroxy-metabolites (HETEs) exist as ena
Publikováno v:
Analytica, Vol 2, Iss 7, Pp 57-65 (2021)
Analytica
Volume 2
Issue 3
Pages 7-65
Analytica
Volume 2
Issue 3
Pages 7-65
Clobazam (CLB) is a benzodiazepine that is used in many types of epilepsy. Although therapeutic drug monitoring (TDM) of CLB is not routine, there is evidence that TDM may be of value in conditions where pharmacokinetic alterations are suspected. The
Publikováno v:
Drug Metabolism and Disposition. :DMD-AR
Publikováno v:
Drug metabolism reviews. 54(2)
Understanding lipid metabolism is a critical key to understanding the pathogenesis of Diabetes Mellitus (DM). It is known that 60-90% of DM patients are obese or used to be obese. The incidence of obesity is rising owing to the modern sedentary lifes