Výsledky vyhledávání - "Fadlo R, Khuri"

Akademický článek

In Lebanon 'It Never Rains But It Pours'—How the American University of Beirut faced dangers and seized opportunities: Transforming medical education through multiple crises

Autor: Fadlo R. Khuri

Publikováno v: FASEB BioAdvances, Vol 3, Iss 9, Pp 676-682 (2021)

Abstract Higher education and healthcare are in the eye of the health, economic, and political storms induced by the COVID‐19 pandemic. Many of the questions that have been raised had been lingering incipiently, but others are legitimately new and

Externí odkaz: https://doaj.org/article/5c95c531f8d04579b115f661db48d207

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Akademický článek

Durvalumab and tremelimumab with or without stereotactic body radiation therapy in relapsed small cell lung cancer: a randomized phase II study

Autor: Chao Zhang, Shuhua Wang, Suresh Ramalingam, Sagar Lonial, Walter Curran, Edmund K Waller, Bassel Nazha, Taofeek K Owonikoko, Conor Steuer, Suchita Pakkala, Kristin Higgins, Zhengjia Chen, Gabriel Sica, Guojing Zhang, Mohammad S Hossain, Tyler Beardslee, Fadlo R Khuri

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)

Background Immune checkpoint blockade (ICB) targeting programmed cell death protein 1 and cytotoxic T lymphocyte-associated protein 4 has achieved modest clinical activity as salvage therapy in relapsed small cell lung cancer (SCLC). We conducted thi

Externí odkaz: https://doaj.org/article/1972602b33d841d1980a59a671248fb6

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Akademický článek

The OncoPPi network of cancer-focused protein–protein interactions to inform biological insights and therapeutic strategies

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)

Understanding of dysregulation in cancers requires knowledge, beyond cancer genomes, of the interactions of cancer-associated proteins. Here, the authors use high-throughput, time-resolved FRET to map protein–protein interactions to establish a lun

Externí odkaz: https://doaj.org/article/68054ffe48384c37b6507f6dc7acbd25

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Akademický článek

Evaluation of preclinical efficacy of everolimus and pasireotide in thyroid cancer cell lines and xenograft models.

Autor: Taofeek K Owonikoko, Guojing Zhang, Shenila B Lallani, Zhengjia Chen, Deborah E Martinson, Fadlo R Khuri, Sagar Lonial, Adam Marcus, Shi-Yong Sun

Publikováno v: PLoS ONE, Vol 14, Iss 2, p e0206309 (2019)

BackgroundSignaling through mTOR and somatostatin pathway is implicated in thyroid cancer development.MethodWe evaluated everolimus, an mTOR inhibitor and pasireotide, a multi receptor somatostatin analogue as potential therapy of thyroid cancer focu

Externí odkaz: https://doaj.org/article/114c0e90df34469385e1e3fecd490a97

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