Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Fadi Saadeh"'
Autor:
Jan Remsik, Yudan Chi, Xinran Tong, Ugur Sener, Camille Derderian, Abigail Park, Fadi Saadeh, Tejus Bale, Adrienne Boire
Publikováno v:
Cancer Reports, Vol 5, Iss 4, Pp n/a-n/a (2022)
Abstract Background Leptomeningeal metastasis (LM), or spread of cancer cells into the cerebrospinal fluid (CSF), is characterized by a rapid onset of debilitating neurological symptoms and markedly bleak prognosis. The lack of reproducible in vitro
Externí odkaz:
https://doaj.org/article/95974a54e7b14fedb35845edf380dcfd
Autor:
Joelle Makoukji, Fadi Saadeh, Karl Albert Mansour, Sally El‐Sitt, Jamal Al Ali, Nihar Kinarivala, Paul C. Trippier, Rose‐Mary Boustany
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 5, Iss 9, Pp 1089-1103 (2018)
Abstract Objective Neuronal Ceroid Lipofuscinoses (NCL) are fatal inherited neurodegenerative diseases with established neuronal cell death and increased ceramide levels in brain, hence, a need for disease‐modifying drug candidates, with potential
Externí odkaz:
https://doaj.org/article/e661f20a7f5146d8aa6824cfbddc37a8
Autor:
Adrienne Boire, Yudan Chi, Jan Remsik, Vaidodas Kiseliovas, Camille Derderian, Ugur Sener, Fadi Saadeh, Katie Nikishina, Tejus Bale, Christine Iacobuzio-Donahue, Tiffany Thomas, Dana Pe’er, Linas Mazutis, Jessica Wilcox
Publikováno v:
WFNOS 2022 Abstract Book.
Autor:
Xinran Tong, Min Jun Li, Fadi Saadeh, Jean Wu, Adrienne Boire, Rajmohan Murali, Ján Remšík, Yudan Chi, Tejus Bale, Jenna Snyder, Camille Derderian, David Guber
Publikováno v:
J Neuroimmunol
Meninges, or the membranous coverings of the brain and spinal cord, play host to dozens of morbid pathologies. In this study we provide a method to isolate the leptomeningeal cell layer, identify leptomeninges in histologic slides, and maintain lepto
The meninges remain an unexplored area of neurobiology. These structures play host to dozens of morbid pathologies. This protocol provides a reliable way to identify and isolate pial cells from mice using robust markers of pial identity in mouse and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6de5628625e95b69e60eb6c81dfa1f7
https://doi.org/10.1101/2021.02.01.429222
https://doi.org/10.1101/2021.02.01.429222
Autor:
Adrienne Boire, Fadi Saadeh
Publikováno v:
Central Nervous System Metastases ISBN: 9783030429577
Leptomeningeal metastasis has been on the rise in liquid and solid malignancies and is often associated with a dismal prognosis. Multifocal neurologic signs and symptoms in patients with primary malignancies should prompt clinicians to assess for lep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::393c5f999d3bfd0a703b0650b17f8977
https://doi.org/10.1007/978-3-030-42958-4_12
https://doi.org/10.1007/978-3-030-42958-4_12
Publikováno v:
Journal of Clinical Neurology (Seoul, Korea)
Treating adult low-grade gliomas (LGGs) is particularly challenging due to the highly infiltrative nature of this type of brain cancer. Although surgery, radiotherapy, and chemotherapy are the mainstay treatment modalities for LGGs, the optimal combi
Autor:
Yudan Chi, Ján Remšík, Adrienne Boire, Tejus Bale, Ugur Sener, Fadi Saadeh, Camille Derderian, Abigail Park, Xinran Tong
Publikováno v:
Cancer Rep (Hoboken)
Background Leptomeningeal metastasis (LM), or spread of cancer cells into the cerebrospinal fluid (CSF), is characterized by a rapid onset of debilitating neurological symptoms and markedly bleak prognosis. The lack of reproducible in vitro and in vi
Publikováno v:
The International Journal of Biological Markers. 33:22-32
Epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein and a member of the tyrosine kinase superfamily receptor. Gliomas are tumors originating from glial cells, which show a range of aggressiveness depending on grade and stage. Many
Autor:
Majdi Alghader, Linas Mazutis, Ugur Sener, Dana Pe'er, Tiffany Thomas, Christine A. Iacobuzio-Donahue, Yudan Chi, Vaidotas Kiseliovas, Adrienne Boire, Camille Derderian, Fadi Saadeh, Katie Nikishina, Ján Remšík, Tejus Bale
Publikováno v:
Science (New York, N.Y.). 369(6501)
Ironing out a survival strategy Metastatic cells display a notable ability to adapt to—and even thrive in—harsh microenvironments. One extreme example is leptomeningeal metastases (LM), cancer cells that enter a region of the central nervous syst