Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Fadi G. Saqallah"'
Autor:
Nurul Hanim Salin, Maywan Hariono, Nur Sarah Dyana Khalili, Iffah Izzati Zakaria, Fadi G. Saqallah, Mohamad Nurul Azmi Mohamad Taib, Ezatul Ezleen Kamarulzaman, Habibah A. Wahab, Muhammad Hidhir Khawory
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
According to the World Health Organisation (WHO), as of week 23 of 2022, there were more than 1,311 cases of dengue in Malaysia, with 13 deaths reported. Furthermore, there was an increase of 65.7% during the same period in 2021. Despite the increase
Externí odkaz:
https://doaj.org/article/37a9c00b1d1941308bc8194666cdbd61
Autor:
Raghdaa Hamdan Al Zarzour, Ezatul Ezleen Kamarulzaman, Fadi G. Saqallah, Fauziahanim Zakaria, Muhammad Asif, Khairul Niza Abdul Razak
Publikováno v:
Heliyon, Vol 8, Iss 9, Pp e10665- (2022)
Extensive attention has been focused on herbal medicine for the treatment of different endocrine disorders. In fact, compelling scientific evidence indicates that natural compounds might act as endocrine modulators by mimicking, stimulating, or inhib
Externí odkaz:
https://doaj.org/article/01d8f2fdc05b45efbfed05afc4889da5
Publikováno v:
Heliyon, Vol 8, Iss 8, Pp e10391- (2022)
Background: Antirrhinum majus (Snapdragon) is a perennial Mediterranean-native plant that is commonly used for mass display. Few reports acknowledged the traditional use of A. majus for its medicinal and therapeutic effects. Herein, we assess the imp
Externí odkaz:
https://doaj.org/article/174adcad06214b528d1b7e4ee3a2a5b4
Autor:
Belal O. Al-Najjar, Fadi G. Saqallah
Publikováno v:
Molecules, Vol 28, Iss 9, p 3878 (2023)
The P2Y12 receptor is an important member of the purinergic receptor family, known for its critical role in platelet activation and thrombosis. In our previously published study, the acridinone analogue NSC618159 was identified as a potent antagonist
Externí odkaz:
https://doaj.org/article/290ca8059d5e429ea72213a3818c13c6
Autor:
Ibrahim M. Abdulbaqi, Reem Abou Assi, Anan Yaghmur, Yusrida Darwis, Noratiqah Mohtar, Thaigarajan Parumasivam, Fadi G. Saqallah, Habibah A. Wahab
Publikováno v:
Pharmaceuticals, Vol 14, Iss 8, p 725 (2021)
Lung cancer (LC) is the leading cause of cancer-related deaths, responsible for approximately 18.4% of all cancer mortalities in both sexes combined. The use of systemic therapeutics remains one of the primary treatments for LC. However, the therapeu
Externí odkaz:
https://doaj.org/article/aaba251449bc4f569ff2718d7a285f46
Autor:
Mohammad G. Al-Thiabat, Fadi G. Saqallah, Amirah Mohd Gazzali, Noratiqah Mohtar, Beow Keat Yap, Yee Siew Choong, Habibah A Wahab
Publikováno v:
Molecules, Vol 26, Iss 4, p 1079 (2021)
Folate receptor alpha (FRα) is known as a biological marker for many cancers due to its overexpression in cancerous epithelial tissue. The folic acid (FA) binding affinity to the FRα active site provides a basis for designing more specific targets
Externí odkaz:
https://doaj.org/article/a08fd84cf58b4731b2bef61e1d951057
Publikováno v:
Scientia Pharmaceutica, Vol 86, Iss 4, p 45 (2018)
Mediterranean-native perennial plant Antirrhinum majus was scrutinized in this study for its antioxidant activity and its total phenolic content in order to test for the plant’s wound-healing capability. The traditional uses of this plant to treat
Externí odkaz:
https://doaj.org/article/e600a58fd04a404e90ba1052bc34fd7e
Publikováno v:
Reviews in Endocrine and Metabolic Disorders. 24:297-316
Publikováno v:
RSC Medicinal Chemistry. 14:239-246
In silico and in vitro discovery of P2Y12 antagonists utilizing structure-based pharmacophore modelling directed by quantitative structure-activity relationship (QSAR) analysis.
Publikováno v:
Phytochemistry. 202
Dengue virus (DENV) is an arbovirus widespread through tropical and subtropical areas. It is transmitted to humans through Aedes mosquitoes. Infections with DENV can lead to a series of complications, including dengue fever, dengue haemorrhagic fever