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A promising antifibrotic drug, pyridoxamine attenuates thioacetamide-induced liver fibrosis by combating oxidative stress, advanced glycation end products, and balancing matrix metalloproteinases.

Autor: Alshanwani AR; Physiology Department, College of Medicine & King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia., Hagar H; Physiology Department, College of Medicine & King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia. Electronic address: hhagar@ksu.edu.sa., Shaheen S; Anatomy Department and Stem Cell Unit, College of Medicine, King Saud University, Riyadh, Saudi Arabia., Alhusaini AM; Pharmacology and Toxicology Department, Faculty of Pharmacy, King Saud University, Riyadh, Saudi Arabia., Arafah MM; Pathology Department, College of Medicine, King Saud University, Riyadh, Saudi Arabia., Faddah LM; Pharmacology and Toxicology Department, Faculty of Pharmacy, King Saud University, Riyadh, Saudi Arabia., Alharbi FM; Biochemistry Department, College of Science, King Saud University, Riyadh, Saudi Arabia., Sharma AK; Pharmacology Department, Amity Institute of Pharmacy, Amity University, Gurugram, Haryana, 122413, India., Fayed A; Clinical Sciences Department, College of Medicine, Princess Nourah Bint Abdulrahman University, Saudi Arabia. Electronic address: aafayed@pnu.edu., Badr AM; Pharmacology and Toxicology Department, Faculty of Pharmacy, King Saud University, Riyadh, Saudi Arabia; Pharmacology and Toxicology Department, College of Pharmacy, Ain Shams University, Cairo, Egypt.

Publikováno v: European journal of pharmacology [Eur J Pharmacol] 2022 May 15; Vol. 923, pp. 174910. Date of Electronic Publication: 2022 Mar 23.

Cyanocobalamin and/or calcitriol mitigate renal damage-mediated by tamoxifen in rats: Implication of caspase-3/NF-κB signaling pathways.

Autor: Alshanwani AR; College of Medicine, Physiology Department, King Saud University, Saudi Arabia. Electronic address: aalshanawani@ksu.edu.sa., Mohamed AM; Therapeutic Chemistry Department, National Research Center, Cairo, Egypt; Biochemistry Department, College of Science, University of Jeddah, Jeddah, Saudi Arabia., Faddah LM; Pharmacology and Toxicology Department, Faculty of Pharmacy, King Saud University, Riyadh, Saudi Arabia., Shaheen S; College of Medicine, Anatomy Department, Stem Cell Unit, King Saud University, Riyadh, Saudi Arabia., Arafah MM; Pathology Department, College of Medicine, King Saud University, Riyadh, Saudi Arabia., Hagar H; College of Medicine, Physiology Department, King Saud University, Saudi Arabia; College of Pharmacy, Pharmacology and Toxicology Department, Zagazig University, Zagazig, Egypt., Alhusaini AM; Pharmacology and Toxicology Department, Faculty of Pharmacy, King Saud University, Riyadh, Saudi Arabia., Alharbi FMB; College of Science, Biochemistry Department, King Saud University, Riyadh, Saudi Arabia., AlHarthii A; Pharmacology and Toxicology Department, Faculty of Pharmacy, King Saud University, Riyadh, Saudi Arabia., Badr AM; Pharmacology and Toxicology Department, Faculty of Pharmacy, King Saud University, Riyadh, Saudi Arabia; Pharmacology and Toxicology Department, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.

Publikováno v: Life sciences [Life Sci] 2021 Jul 15; Vol. 277, pp. 119512. Date of Electronic Publication: 2021 Apr 16.

Vitamin C and Turmeric Attenuate Bax and Bcl-2 Proteins' Expressions and DNA Damage in Lead Acetate-Induced Liver Injury.

Autor: Alhusaini AM; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia., Faddah LM; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia., Hasan IH; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia., Jarallah SJ; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia., Alghamdi SH; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia., Alhadab NM; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia., Badr A; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.; Department of Pharmacology and Toxicology, College of Pharmacy, AIN Shams University, Egypt., Elorabi N; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt., Zakaria E; Department of Pharmaceutics Department, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia., Al-Anazi A; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.

Publikováno v: Dose-response : a publication of International Hormesis Society [Dose Response] 2019 Nov 19; Vol. 17 (4), pp. 1559325819885782. Date of Electronic Publication: 2019 Nov 19 (Print Publication: 2019).

Amelioration of panadol-induced nephrotoxicity via down-regulation of Bax/Bcl2 ratio with some antioxidants.

Autor: Al-Rasheed N; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia., Faddah LM; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia., Hasan IH; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia., Ali HM; Department of Genetics and Cytology, National Research Centre, Dokki, Gizza, Egypt; First Year Common Deanship, King Saud University, Riyadh, Saudi Arabia. Electronic address: hsameh2312003@yahoo.com., Al-Rasheed N; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia; Department of Pharmaceutical Sciences, College of Pharmacy, Princess NourahBint Abdulrahman University, Riyadh, Saudi Arabia., El Oraby NF; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia; Department of Pharmacology and Toxicology, Suez Canal University, Ismailia, Egypt., Mohamed MH; Nutrition and Food Science Department, National Research Centre, Dokki, Gizza, Egypt.

Publikováno v: Pharmacological reports : PR [Pharmacol Rep] 2017 Oct; Vol. 69 (5), pp. 1088-1093. Date of Electronic Publication: 2017 May 06.