Výsledky vyhledávání - "Facundo Martín Bertera"

Development of Subcutaneous Implants of Controlled Release Formulations of Carvedilol for Sustained Blood Pressure Reduction in Experimental Models of Hypertension

Autor: Facundo Martín Bertera, Camila Melody Boquete, Miguel Ángel Allo, Diego A. Chiappetta, Luciano Parola, Christian Höcht, Yanina Santander Pantamura, Marcela A. Moretton

Publikováno v: Revista Argentina de Cardiologia. 88:125-129

espanolObjetivo: El objetivo del presente estudio fue el desarrollo y la evaluacion farmacocinetica y farmacodinamica de la liberacionin vivo de implantes subcutaneos de carvedilol capaces de aportar niveles tisulares estables en modelos experimental

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::84336b5e88664ad746f26fc01f42af89
https://doi.org/10.7775/rac.es.v88.i2.17472

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Factors influencing hepatic metabolism of antihypertensive drugs: impact on clinical response

Autor: Julieta Sofía del Mauro, Facundo Martín Bertera, Yanina Santander Plantamura, Christian Höcht, Luciano Parola, Ariel H. Polizio

Introduction: Although main antihypertensive drugs are able to efficiently reduce blood pressure, only a third of treated hypertensive patients achieve optimal blood pressure control. Extensive interpatient variability on drug metabolism and oral dis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47dbfe54f0c5e499c53012a0724f66b8
https://www.tandfonline.com/doi/full/10.1080/17425255.2019.1558204

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PK/PD modeling of β-blockers in cardiovascular disease: an update

Autor: Julieta Sofía del Mauro, Luciano Parola, Facundo Martín Bertera, Christian Höcht, Carlos A. Taira

Publikováno v: International Journal of Pharmacokinetics. 1:55-68

β-blockers play a central role in the treatment of the various main cardiovascular diseases, including hypertension, coronary artery disease and systolic heart failure. As a therapeutic class, β-blockers form a heterogeneous family that differs in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::46f768afb1371ad93fa867bb313f75a5
https://doi.org/10.4155/ipk-2016-0008

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What is the Real Efficacy of Beta-Blockers for the Treatment of Essential Hypertension?

Autor: Julieta Sofía del Mauro, Christian Höcht, Facundo Martín Bertera, Ariel H. Polizio, Carlos A. Taira, Yanina Santander Plantamura

Publikováno v: Current Pharmaceutical Design. 23

Objective This review covers the pharmacokinetics and pharmacodynamic of β-blockers, the rationale for their use, some recent controversies in its use for managing hypertension, as well as, the beneficial properties of the third-generation β-blocke

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6e59967f24f7a7e32228b9ee2fbe7ca
https://doi.org/10.2174/1381612823666170608085109

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Advances in therapy for the prevention of HIV transmission from mother to child

Autor: Diego A. Chiappetta, Eduardo Lagomarsino, Jennifer Denise Riedel, Facundo Martín Bertera, Marcela A. Moretton, Christian Höcht

Introduction: Actually, ~17.8 million women and 1.8 million children (90%) resulted from ‘HIV mother-to-child transmission’ (MTCT), both in pregnancy, labour, delivery and later by breastfeeding. Due to its high pediatric incidence, MTCT represen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1402bab4d4208a30f3926a8efe74754f
https://www.tandfonline.com/doi/full/10.1080/14656566.2017.1316369

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Effects of carvedilol or amlodipine on target organ damage in L-NAME hypertensive rats: their relationship with blood pressure variability

Autor: Martín Donato, Andrea Carranza, Julieta Sofía del Mauro, Celina Morales, Marcela A. Moretton, Susana Gorzalczany, Facundo Martín Bertera, Paula D. Prince, Germán González, Diego A. Chiappetta, Ricardo J. Gelpi, Nahuel Fernandez Machulsky, Gabriela Berg, Carlos A. Taira, Christian Höcht

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

The aim of the study was to compare the effects of chronic oral treatment with carvedilol or amlodipine on blood pressure, blood pressure variability and target organ damage in N-nitro-l-arginine methyl ester (L-NAME) hypertensive rats. Wistar rats w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c23314b57fcd9f4c88dbbaab755cf3e
http://linkinghub.elsevier.com/retrieve/pii/S193317111730044X

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Tempol-nebivolol therapy potentiates hypotensive effect increasing NO bioavailability and signaling pathway

Autor: Karina B. Balestrasse, Susana Gorzalczany, Ariel H. Polizio, Diego M. Santa-Cruz, Facundo Martín Bertera, Carlos A. Taira, Chistian Höcht

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Nebivolol is a third generation beta blocker with endothelial nitric oxide synthase (eNOS) agonist properties. Considering the role of reactive oxygen species (ROS) in the uncoupling of eNOS, we hypothesized that the preadministration of an antioxida

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2057a20f98ae0ed5379265baccec66e
https://doi.org/10.3109/10715762.2013.845294

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