Zobrazeno 1 - 10
of 265
pro vyhledávání: '"Facundo M. Fernández"'
Autor:
Priyanka Priyadarshani, Alexandria Van Grouw, Adrian Ross Liversage, Kejie Rui, Arina Nikitina, Kayvan Forouhesh Tehrani, Bhavay Aggarwal, Steven L. Stice, Saurabh Sinha, Melissa L. Kemp, Facundo M. Fernández, Luke J. Mortensen
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114579- (2024)
Summary: Mesenchymal stem/stromal cell (MSC) therapies have had limited success so far in clinical trials due in part to heterogeneity in immune-responsive phenotypes. Therefore, techniques to characterize these properties of MSCs are needed during b
Externí odkaz:
https://doaj.org/article/e49e2cf5a48945ed8e369bccbdaa582a
Autor:
Dmitry Leontyev, Alexis N. Pulliam, Xin Ma, David A. Gaul, Michelle C. LaPlaca, Facundo M. Fernández
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
Traumatic brain injury (TBI) is a global public health problem with 50–60 million incidents per year, most of which are considered mild (mTBI) and many of these repetitive (rmTBI). Despite their massive implications, the pathologies of mTBI and rmT
Externí odkaz:
https://doaj.org/article/3b4bf857901244bca9a349fa7bb067a4
Autor:
Xin Ma, Andro Botros, Sylvia R. Yun, Eun Young Park, Olga Kim, Soojin Park, Thu-Huyen Pham, Ruihong Chen, Murugesan Palaniappan, Martin M. Matzuk, Jaeyeon Kim, Facundo M. Fernández
Publikováno v:
Frontiers in Chemistry, Vol 11 (2024)
No effective screening tools for ovarian cancer (OC) exist, making it one of the deadliest cancers among women. Considering that little is known about the detailed progression and metastasis mechanism of OC at a molecular level, it is crucial to gain
Externí odkaz:
https://doaj.org/article/4136372308ec4b55ab4eeaf71e2b8aa3
Autor:
Philip Fernandes, Yash Sharma, Fatima Zulqarnain, Brooklyn McGrew, Aman Shrivastava, Lubaina Ehsan, Dawson Payne, Lillian Dillard, Deborah Powers, Isabelle Aldridge, Jason Matthews, Subra Kugathasan, Facundo M. Fernández, David Gaul, Jason A. Papin, Sana Syed
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Crohn's disease (CD) is a chronic inflammatory disease of the gastrointestinal tract. A clear gap in our existing CD diagnostics and current disease management approaches is the lack of highly specific biomarkers that can be used to streamli
Externí odkaz:
https://doaj.org/article/0c627d7cb952461686b3ff7a2a7f13f8
Autor:
Alexis N. Pulliam, Alyssa F. Pybus, David A. Gaul, Samuel G. Moore, Levi B. Wood, Facundo M. Fernández, Michelle C. LaPlaca
Publikováno v:
Metabolites, Vol 14, Iss 3, p 133 (2024)
Traumatic brain injury (TBI) is a significant source of disability in the United States and around the world and may lead to long-lasting cognitive deficits and a decreased quality of life for patients across injury severities. Following the primary
Externí odkaz:
https://doaj.org/article/aeea03b3b0b24d62b6e2747b295ee6b3
Autor:
Hani Habra, Jennifer L. Meijer, Tong Shen, Oliver Fiehn, David A. Gaul, Facundo M. Fernández, Kaitlin R. Rempfert, Thomas O. Metz, Karen E. Peterson, Charles R. Evans, Alla Karnovsky
Publikováno v:
Metabolites, Vol 14, Iss 2, p 125 (2024)
Liquid chromatography–high-resolution mass spectrometry (LC-HRMS), as applied to untargeted metabolomics, enables the simultaneous detection of thousands of small molecules, generating complex datasets. Alignment is a crucial step in data processin
Externí odkaz:
https://doaj.org/article/ab4466185f434c298b44e5983418504f
Autor:
Moran Frenkel-Pinter, Marcos Bouza, Facundo M. Fernández, Luke J. Leman, Loren Dean Williams, Nicholas V. Hud, Aikomari Guzman-Martinez
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
One of the early processes enabling the origins of life is thought to be the condensation of building blocks into oligomers and polymers. In this article, the authors report the synthesis of thiodepsipeptides and HS-peptides under mild temperatures a
Externí odkaz:
https://doaj.org/article/df6d52a3f47240ee80e477d8bbe3f713
Autor:
Amanda O. Shaver, Brianna M. Garcia, Goncalo J. Gouveia, Alison M. Morse, Zihao Liu, Carter K. Asef, Ricardo M. Borges, Franklin E. Leach, Erik C. Andersen, I. Jonathan Amster, Facundo M. Fernández, Arthur S. Edison, Lauren M. McIntyre
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Untargeted metabolomics studies are unbiased but identifying the same feature across studies is complicated by environmental variation, batch effects, and instrument variability. Ideally, several studies that assay the same set of metabolic features
Externí odkaz:
https://doaj.org/article/9d83b8419e124151806b3aaea729b8cd
Autor:
Yafeng Li, Marcos Bouza, Changsheng Wu, Hengyu Guo, Danning Huang, Gilad Doron, Johnna S. Temenoff, Arlene A. Stecenko, Zhong Lin Wang, Facundo M. Fernández
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The analysis of metabolites offers promises in biomarker discovery. Here the authors demonstrate the metabolomics analysis of sub-nanoliter samples using triboelectric nanogenerator inductive nanoelectrospray ionization, which they apply to exhaled b
Externí odkaz:
https://doaj.org/article/854b6b4ffa1f4bf9aea9c90c9d4b7608
Autor:
Samyukta Sah, Sylvia R. Yun, David A. Gaul, Andro Botros, Eun Young Park, Olga Kim, Jaeyeon Kim, Facundo M. Fernández
Publikováno v:
Metabolites, Vol 12, Iss 6, p 532 (2022)
The lack of effective screening strategies for high-grade serous carcinoma (HGSC), a subtype of ovarian cancer (OC) responsible for 70–80% of OC related deaths, emphasizes the need for new diagnostic markers and a better understanding of disease pa
Externí odkaz:
https://doaj.org/article/30c1911e3268490b852c487f88f84e43