Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Facundo Fiocca Vernengo"'
Autor:
Morgan Essex, Belén Millet Pascual-Leone, Ulrike Löber, Mathias Kuhring, Bowen Zhang, Ulrike Brüning, Raphaela Fritsche-Guenther, Marta Krzanowski, Facundo Fiocca Vernengo, Sophia Brumhard, Ivo Röwekamp, Agata Anna Bielecka, Till Robin Lesker, Emanuel Wyler, Markus Landthaler, Andrej Mantei, Christian Meisel, Sandra Caesar, Charlotte Thibeault, Victor M. Corman, Lajos Marko, Norbert Suttorp, Till Strowig, Florian Kurth, Leif E. Sander, Yang Li, Jennifer A. Kirwan, Sofia K. Forslund, Bastian Opitz
Publikováno v:
npj Biofilms and Microbiomes, Vol 10, Iss 1, Pp 1-15 (2024)
Abstract The clinical course of COVID-19 is variable and often unpredictable. To test the hypothesis that disease progression and inflammatory responses associate with alterations in the microbiome and metabolome, we analyzed metagenome, metabolome,
Externí odkaz:
https://doaj.org/article/3800ac4d0de04e14b83d18bba159a41d
Autor:
Patrick J. Dörner, Harithaa Anandakumar, Ivo Röwekamp, Facundo Fiocca Vernengo, Belén Millet Pascual-Leone, Marta Krzanowski, Josua Sellmaier, Ulrike Brüning, Raphaela Fritsche-Guenther, Lennart Pfannkuch, Florian Kurth, Miha Milek, Vanessa Igbokwe, Ulrike Löber, Birgitt Gutbier, Markus Holstein, Gitta Anne Heinz, Mir-Farzin Mashreghi, Leon N. Schulte, Ann-Brit Klatt, Sandra Caesar, Sandra-Maria Wienhold, Stefan Offermanns, Matthias Mack, Martin Witzenrath, Stefan Jordan, Dieter Beule, Jennifer A. Kirwan, Sofia K. Forslund, Nicola Wilck, Hendrik Bartolomaeus, Markus M. Heimesaat, Bastian Opitz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Hospital-acquired pneumonia (HAP) is associated with high mortality and costs, and frequently caused by multidrug-resistant (MDR) bacteria. Although prior antimicrobial therapy is a major risk factor for HAP, the underlying mechanism remains
Externí odkaz:
https://doaj.org/article/41a8a643c26b41c0b66352c312b98b9b
Autor:
Melisa Gorosito Serrán, Facundo Fiocca Vernengo, Laura Almada, Cristian G. Beccaria, Yamila Gazzoni, Pablo F. Canete, Jonathan A. Roco, Jimena Tosello Boari, Maria Cecilia Ramello, Ellen Wehrens, Yeping Cai, Elina I. Zuniga, Carolina L. Montes, Ian A. Cockburn, Eva V. Acosta Rodriguez, Carola G. Vinuesa, Adriana Gruppi
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
During infections with protozoan parasites or some viruses, T cell immunosuppression is generated simultaneously with a high B cell activation. It has been described that, as well as producing antibodies, plasmablasts, the differentiation product of
Externí odkaz:
https://doaj.org/article/e2cf7f337a5340039ee73c984b6bf218
Autor:
Ann-Brit Klatt, Christina Diersing, Juliane Lippmann, Sabine Mayer-Lambertz, Felix Stegmann, Swantje Fischer, Sandra Caesar, Facundo Fiocca Vernengo, Katja Hönzke, Andreas C. Hocke, Jürgen Ruland, Martin Witzenrath, Bernd Lepenies, Bastian Opitz
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3891 (2023)
Legionella pneumophila is an intracellular pathogen that can cause severe pneumonia after the inhalation of contaminated aerosols and replication in alveolar macrophages. Several pattern recognition receptors (PRRs) have been identified that contribu
Externí odkaz:
https://doaj.org/article/06f10b21fcfb49f4942c768fca318c2a
Autor:
Facundo Fiocca Vernengo, Cristian G. Beccaria, Cintia L. Araujo Furlan, Jimena Tosello Boari, Laura Almada, Melisa Gorosito Serrán, Yamila Gazzoni, Carolina L. Montes, Eva V. Acosta Rodríguez, Adriana Gruppi
Publikováno v:
mBio, Vol 11, Iss 3 (2020)
ABSTRACT Treatment with anti-CD20, used in many diseases in which B cells play a pathogenic role, has been associated with susceptibility to intracellular infections. Here, we studied the effect of anti-CD20 injection on CD8+ T cell immunity using an
Externí odkaz:
https://doaj.org/article/cb2cab0b6ad84a64815d58f1f221012c
Autor:
Cristian Gabriel Beccaria, María Carolina Amezcua Vesely, Facundo Fiocca Vernengo, Ricardo Carlos Gehrau, María Cecilia Ramello, Jimena Tosello Boari, Melisa Gorosito Serrán, Juan Mucci, Eliane Piaggio, Oscar Campetella, Eva Virginia Acosta Rodríguez, Carolina Lucía Montes, Adriana Gruppi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Germinal center (GC) is where B cells interact with other immune cells for optimal induction of antibody responses. Here the authors show that galectin-3 regulates GC development by modulating interferon-γ and B cell-intrinsic signaling, such that g
Externí odkaz:
https://doaj.org/article/e56f9c7562ff48e1b8ef2534da1247d2
Autor:
Leonardo R. Sanchez, Gloria J. Godoy, Melisa Gorosito Serrán, Maria L. Breser, Facundo Fiocca Vernengo, Pablo Engel, Ruben D. Motrich, Adriana Gruppi, Virginia E. Rivero
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
A significant proportion of individuals develop chronic, persistent and recurrent genital tract infections with Chlamydia trachomatis, which has been attributed to the numerous strategies that the bacterium uses to subvert host immune responses. Anim
Externí odkaz:
https://doaj.org/article/c3d6a144a14f4e5289f02b478640e7f6
Autor:
Cintia L. Araujo Furlan, Jimena Tosello Boari, Constanza Rodriguez, Fernando P. Canale, Facundo Fiocca Vernengo, Santiago Boccardo, Cristian G. Beccaria, Véronique Adoue, Olivier Joffre, Adriana Gruppi, Carolina L. Montes, Eva V. Acosta Rodriguez
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
While it is now acknowledged that CD4+ T cells expressing CD25 and Foxp3 (Treg cells) regulate immune responses and, consequently, influence the pathogenesis of infectious diseases, the regulatory response mediated by Treg cells upon infection by Try
Externí odkaz:
https://doaj.org/article/89675fb7b2c64350af68960726eb620a
Autor:
Jimena Tosello Boari, Cintia L. Araujo Furlan, Facundo Fiocca Vernengo, Constanza Rodriguez, María C. Ramello, María C. Amezcua Vesely, Melisa Gorosito Serrán, Nicolás G. Nuñez, Wilfrid Richer, Eliane Piaggio, Carolina L. Montes, Adriana Gruppi, Eva V. Acosta Rodríguez
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The IL-17 family contributes to host defense against many intracellular pathogens by mechanisms that are not fully understood. CD8+ T lymphocytes are key elements against intracellular microbes, and their survival and ability to mount cytotoxic respo
Externí odkaz:
https://doaj.org/article/079d5f04e628454aa28f96a60e4aaed2
Autor:
Melisa Gorosito Serrán, Jimena Tosello Boari, Facundo Fiocca Vernengo, Cristian G. Beccaría, María C. Ramello, Daniela A. Bermejo, Amelia G. Cook, Carola G. Vinuesa, Carolina L. Montes, Eva V. Acosta Rodriguez, Adriana Gruppi
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Chagas disease, caused by the parasite Trypanosoma cruzi, is endemic in Latin America but has become a global public health concern by migration of infected people. It has been reported that parasite persistence as well as the intensity of the inflam
Externí odkaz:
https://doaj.org/article/b227416f13764d8c86e92c05631e1f2b