Astrocyte-selective AAV-ADAMTS4 gene therapy combined with hindlimb rehabilitation promotes functional recovery after spinal cord injury

Autor: Griffin, Jarred M., Fackelmeier, Barbara, Clemett, Connor A., Fong, Dahna M., Mouravlev, Alexandre, Young, Deborah, O'Carroll, Simon J.

Publikováno v: In Experimental Neurology May 2020 327

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Additional file 1: Figure S1. of PSA-NCAM positive neural progenitors stably expressing BDNF promote functional recovery in a mouse model of spinal cord injury

Autor: Butenschรถn, Jennifer, Zimmermann, Tina, Schmarowski, Nikolai, Nitsch, Robert, Fackelmeier, Barbara, Friedemann, Kevin, Radyushkin, Konstantin, Baumgart, Jan, Lutz, Beat, Leschik, Julia

Efficient BrdU labeling and in vitro detection of sorted neural progenitors. A Representative bright-field (BF) image showing sorted PSA-NCAM-positive cells. B BrdU treatment resulted in a uniform fluorescent staining of the nuclei (blue). C All cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70bc82ec8ac1f67ad7f013867547a313

PSA-NCAM positive neural progenitors stably expressing BDNF promote functional recovery in a mouse model of spinal cord injury.

Autor: Butenschön J; Institute of Physiological Chemistry, University Medical Center, Johannes Gutenberg University, Duesbergweg 6, 55128, Mainz, Germany. jwerne01@students.uni-mainz.de., Zimmermann T; Institute of Physiological Chemistry, University Medical Center, Johannes Gutenberg University, Duesbergweg 6, 55128, Mainz, Germany. tina.zimmermann@uni-mainz.de., Schmarowski N; Institute of Microscopic Anatomy and Neurobiology, University Medical Center, Johannes Gutenberg University, Langenbeckstrasse 1, 55131, Mainz, Germany. nikolai.schmarowski@unimedizin-mainz.de., Nitsch R; Institute of Microscopic Anatomy and Neurobiology, University Medical Center, Johannes Gutenberg University, Langenbeckstrasse 1, 55131, Mainz, Germany. robert.nitsch@uni-mainz.de., Fackelmeier B; Institute of Physiological Chemistry, University Medical Center, Johannes Gutenberg University, Duesbergweg 6, 55128, Mainz, Germany. barbsfa@googlemail.com., Friedemann K; Institute of Physiological Chemistry, University Medical Center, Johannes Gutenberg University, Duesbergweg 6, 55128, Mainz, Germany. kfriedem@uni-mainz.de.; Institute of Microscopic Anatomy and Neurobiology, University Medical Center, Johannes Gutenberg University, Langenbeckstrasse 1, 55131, Mainz, Germany. kfriedem@uni-mainz.de.; Mouse Behavior Outcome Unit, Focus Program Translational Neurosciences (FTN), Johannes Gutenberg University, Hanns-Dieter-Hüsch-Weg 19, 55128, Mainz, Germany. kfriedem@uni-mainz.de., Radyushkin K; Mouse Behavior Outcome Unit, Focus Program Translational Neurosciences (FTN), Johannes Gutenberg University, Hanns-Dieter-Hüsch-Weg 19, 55128, Mainz, Germany. radyushkin@uni-mainz.de., Baumgart J; Institute of Microscopic Anatomy and Neurobiology, University Medical Center, Johannes Gutenberg University, Langenbeckstrasse 1, 55131, Mainz, Germany. jan.baumgart@unimedizin-mainz.de.; Translational Animal Research Center (TARC), University Medical Center, Johannes Gutenberg University, Hanns-Dieter-Hüsch-Weg 19, 55128, Mainz, Germany. jan.baumgart@unimedizin-mainz.de., Lutz B; Institute of Physiological Chemistry, University Medical Center, Johannes Gutenberg University, Duesbergweg 6, 55128, Mainz, Germany. blutz@uni-mainz.de., Leschik J; Institute of Physiological Chemistry, University Medical Center, Johannes Gutenberg University, Duesbergweg 6, 55128, Mainz, Germany. leschik@uni-mainz.de.

Publikováno v: Stem cell research & therapy [Stem Cell Res Ther] 2016 Jan 13; Vol. 7, pp. 11. Date of Electronic Publication: 2016 Jan 13.