Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Fabrizio Machetti"'
Publikováno v:
Reactions, Vol 5, Iss 3, Pp 492-566 (2024)
The present review is a comprehensive update of the synthesis of monocyclic β-lactams via cycloaddition reactions. According to the IUPAC definition of cycloaddition, both elementary and stepwise processes (formal cycloadditions) have been considere
Externí odkaz:
https://doaj.org/article/3a9a9b9e0b364381b0dd406a91f66604
Publikováno v:
Molbank, Vol 2024, Iss 1, p M1762 (2024)
We describe here the palladium hydrogenation of ethyl 5-(benzoyloxymethyl)isoxazole-3-carboxylate. The presence of two reducible sites in the molecule, namely the benzylic-like position and the isoxazole N–O bond, creates a possible competition. Th
Externí odkaz:
https://doaj.org/article/c26f6ae7d2c04d6b8e379fc09a2c15cb
Autor:
Giovanni La Penna, Fabrizio Machetti
Publikováno v:
Molecules, Vol 29, Iss 1, p 9 (2023)
Many computational methods have been applied to interpret and predict changes in reactivity by slight modifications of a given molecular scaffold. We describe a novel and simple method based on approximate density-functional theory of valence electro
Externí odkaz:
https://doaj.org/article/42fa57a7a78c48d488b13a1a50c9dce1
Autor:
Giovanni La Penna, Fabrizio Machetti
Publikováno v:
Molecules, Vol 23, Iss 12, p 3308 (2018)
Proton transfer in water involving C⁻H bonds is a challenge and nitro compounds have been studied for many years as good examples. The effect of substituents on acidity of protons geminal to the nitro group is exploited here with new p K a measurem
Externí odkaz:
https://doaj.org/article/8a784c933b3f472eaa9adb1861e65228
Autor:
Giovanni La Penna, Olivier Proux, Silvia Morante, Francesco Stellato, Fabrizio Machetti, Giancarlo Rossi
Publikováno v:
Journal of physical chemistry. C 125 (2021): 1483–1492. doi:10.1021/acs.jpcc.0c08676
info:cnr-pdr/source/autori:La Penna G.; Machetti F.; Proux O.; Rossi G.; Stellato F.; Morante S./titolo:Cu(II)-Glycerol-N-Ethylmorpholine Complex Stability Revealed by X-ray Spectroscopy/doi:10.1021%2Facs.jpcc.0c08676/rivista:Journal of physical chemistry. C/anno:2021/pagina_da:1483/pagina_a:1492/intervallo_pagine:1483–1492/volume:125
info:cnr-pdr/source/autori:La Penna G.; Machetti F.; Proux O.; Rossi G.; Stellato F.; Morante S./titolo:Cu(II)-Glycerol-N-Ethylmorpholine Complex Stability Revealed by X-ray Spectroscopy/doi:10.1021%2Facs.jpcc.0c08676/rivista:Journal of physical chemistry. C/anno:2021/pagina_da:1483/pagina_a:1492/intervallo_pagine:1483–1492/volume:125
We report on a detailed X-ray absorption spectroscopy study of the Cu(II) coordination mode in aqueous solution in the presence of glycerol cryoprotectant and N-ethylmorpholine buffer. The first additive is often used when working at very low tempera
Publikováno v:
European Journal of Organic Chemistry. 2020:1720-1726
Publikováno v:
Comprehensive Heterocyclic Chemistry IV ISBN: 9780128186565
Isoxazoles, benzisoxazoles, isoxazolines, and isoxazolidines are classes of heterocyclic compounds having a remarkable number of applications and are very versatile building blocks in organic synthesis. The major developments on the chemistry of thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3303a7dee9776560535c88d974e62d39
https://doi.org/10.1016/b978-0-12-818655-8.00135-9
https://doi.org/10.1016/b978-0-12-818655-8.00135-9
Autor:
Giacomo Biagiotti, Fabrizio Machetti, Maria Cristina Ligi, Helen Piwnica-Worms, Emily Powell, Erica Pranzini, Federica Pisaneschi, Stefano Cicchi, Giulia Tuci, David Piwnica-Worms, Seth T. Gammon, Paolo De Paoli, Giuliano Giambastiani
Publikováno v:
Journal of Materials Chemistry B 7 (2019): 2678–2687. doi:10.1039/c8tb03299h
info:cnr-pdr/source/autori:Biagiotti, Giacomo; Pisaneschi, Federica; Gammon, T. Seth; Machetti, Fabrizio; Ligi, Maria Cristina; Giambastiani, Giuliano; Tuci, Giulia; Powell, Emily; Piwnica-Worms, Helen; Pranzini, Erica; Paoli, Paolo; Cicchi, Stefano; Piwnica-Worms, David/titolo:Multiwalled carbon nanotubes for combination therapy: A biodistribution and efficacy pilot study/doi:10.1039%2Fc8tb03299h/rivista:Journal of Materials Chemistry B/anno:2019/pagina_da:2678/pagina_a:2687/intervallo_pagine:2678–2687/volume:7
info:cnr-pdr/source/autori:Biagiotti, Giacomo; Pisaneschi, Federica; Gammon, T. Seth; Machetti, Fabrizio; Ligi, Maria Cristina; Giambastiani, Giuliano; Tuci, Giulia; Powell, Emily; Piwnica-Worms, Helen; Pranzini, Erica; Paoli, Paolo; Cicchi, Stefano; Piwnica-Worms, David/titolo:Multiwalled carbon nanotubes for combination therapy: A biodistribution and efficacy pilot study/doi:10.1039%2Fc8tb03299h/rivista:Journal of Materials Chemistry B/anno:2019/pagina_da:2678/pagina_a:2687/intervallo_pagine:2678–2687/volume:7
A drug delivery system (DDS) for combined therapy, based on a short oxidized multiwalled carbon nanotube, is reported. It was prepared by exploiting a synthetic approach which allowed loading of two drugs, doxorubicin and metformin, the targeting age
Autor:
Martina, Banchelli, Roberta, Cascella, Cristiano, D'Andrea, Giovanni, La Penna, Mai Suan, Li, Fabrizio, Machetti, Paolo, Matteini, Silvia, Pizzanelli
Publikováno v:
ACS chemical neuroscience. 12(7)
Structural models of the toxic species involved in the development of Alzheimer's disease are of utmost importance to understand the molecular mechanism and to describe early biomarkers of the disease. Among toxic species, soluble oligomers of amyloi
Publikováno v:
European Journal of Organic Chemistry. 2016:4643-4655
Isoxazoles, mainly 3,5-disubstituted, are prepared by catalytic condensation of primary nitro compounds with terminal acetylenes by using a copper/base catalytic system. The additional catalytic effect of the copper(II) salts is evidenced by comparin