Výsledky vyhledávání - "Fabrizio Conci"

Pharmacologic data reveal the heterogeneity of anaiotensin-converting enzyme according to its source (lung versus heart)

Autor: Tarcisio Vago, Maurizio Bevilacqua, Fabrizio Conci, Guido Norbiato, Angela Rogolino

Publikováno v: The American Journal of Cardiology. 75:13F-17F

Angiotensin-converting enzyme (ACE) has 2 different active sites: a C-site (in the carboxy terminal region) and an N-site (in the amino terminal part). Some ACE inhibitors have a relatively greater affinity for the C-sites, whereas others bind to the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::896a7f7cb0ce5706a352ebe48cd7bb2c
https://doi.org/10.1016/s0002-9149(99)80509-8

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Affinity of angiotensin I-converting enzyme (ACE) inhibitors for N- and C-binding sites of human ACE is different in heart, lung, arteries, and veins

Autor: Maurizio Bevilacqua, Edoardo Santoli, Tarcisio Vago, Guido Norbiato, Fabrizio Conci, Angela Rogolino

Publikováno v: Journal of cardiovascular pharmacology. 28(4)

Angiotensin-converting enzyme (ACE) has two enzymatically active domains: a C-domain in the carboxy terminal region and an N-domain in the amino terminal region. We based the pharmacologic characterization of these sites on the rat testis-lung model.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bb5291939a10c395d136237801700c6
https://pubmed.ncbi.nlm.nih.gov/8891872

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