Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Fabrizio Alberti"'
Autor:
Songya Zhang, Lin Zhang, Anja Greule, Julien Tailhades, Edward Marschall, Panward Prasongpholchai, Daniel J. Leng, Jingfan Zhang, Jing Zhu, Joe A. Kaczmarski, Ralf B. Schittenhelm, Oliver Einsle, Colin J. Jackson, Fabrizio Alberti, Andreas Bechthold, Youming Zhang, Manuela Tosin, Tong Si, Max J. Cryle
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 8, Pp 3561-3574 (2023)
WS9326A is a peptide antibiotic containing a highly unusual N-methyl-E-2-3-dehydrotyrosine (NMet-Dht) residue that is incorporated during peptide assembly on a non-ribosomal peptide synthetase (NRPS). The cytochrome P450 encoded by sas16 (P450Sas) ha
Externí odkaz:
https://doaj.org/article/7d63ec27ecab4b6da2493ecc0f966b70
Autor:
Deepa Paliwal, Amanda J. Hamilton, Glyn A. Barrett, Fabrizio Alberti, Helmut vanEmden, Caroline L. Monteil, Tim H. Mauchline, Ralf Nauen, Carol Wagstaff, Chris Bass, Robert W. Jackson
Publikováno v:
Microbial Biotechnology, Vol 15, Iss 4, Pp 1203-1220 (2022)
Summary Aphids, including the peach‐potato aphid, Myzus persicae, are major insect pests of agriculture and horticulture, and aphid control measures are limited. There is therefore an urgent need to develop alternative and more sustainable means of
Externí odkaz:
https://doaj.org/article/5244dc766cc2470ba11d7ef208b9d22e
Publikováno v:
Journal of Fungi, Vol 9, Iss 9, p 895 (2023)
Fungi represents a rich repository of taxonomically restricted, yet chemically diverse, secondary metabolites that are synthesised via specific metabolic pathways. An enzyme’s specificity and biosynthetic gene clustering are the bottleneck of secon
Externí odkaz:
https://doaj.org/article/975e37ce25c947f2a32414666b0a5fea
Publikováno v:
Biology Open, Vol 9, Iss 12 (2020)
Basidiomycota are a large and diverse phylum of fungi. They can make bioactive metabolites that are used or have inspired the synthesis of antibiotics and agrochemicals. Terpenoids are the most abundant class of natural products encountered in this t
Externí odkaz:
https://doaj.org/article/1a4e23dad3f9412a8fa113503cb75e33
Autor:
Amin-Asyraf Tamizi, Noriha Mat-Amin, Jack A. Weaver, Richard T. Olumakaiye, Muhamad Afiq Akbar, Sophie Jin, Hamidun Bunawan, Fabrizio Alberti
Publikováno v:
Journal of Fungi, Vol 8, Iss 3, p 246 (2022)
Erwinia mallotivora, the causal agent of papaya dieback disease, is a devastating pathogen that has caused a tremendous decrease in Malaysian papaya export and affected papaya crops in neighbouring countries. A few studies on bacterial species capabl
Externí odkaz:
https://doaj.org/article/c75685e3254441d99d6f4c9221d7923f
Autor:
Fabrizio Alberti, Khairunisa Khairudin, Edith Rodriguez Venegas, Jonathan A. Davies, Patrick M. Hayes, Christine L. Willis, Andy M. Bailey, Gary D. Foster
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Pleuromutilin derivatives are potent antibacterial drugs obtained from Basidiomycete fungi. Here, the authors report the genetic characterisation of the steps involved in pleuromutilin biosynthesis through heterologous expression and generate a semi-
Externí odkaz:
https://doaj.org/article/69ed545afbdf4bf8aca81334cecd634a
Autor:
Fabrizio Alberti
Publikováno v:
Exchanges, Vol 4, Iss 1, Pp 158-166 (2016)
Natural products are compounds that are produced by living organisms. They have numerous applications in our everyday life, from antibiotics to herbicides. They possess great chemical and structural diversity, which gives them a leading position as a
Externí odkaz:
https://doaj.org/article/bce87889692546caacbc35091df4c56b
Autor:
Fabrizio Alberti, Khairunisa Khairudin, Jonathan A. Davies, Suphattra Sangmalee, Christine L. Willis, Gary D. Foster, Andy M. Bailey
Publikováno v:
Chemical Science. 14:3826-3833
We report two shunt pathways that expand our knowledge on the biosynthesis of the antibiotic pleuromutilin. Three new congeners of pleuromutilin were isolated, alongside the semi-synthesis of a novel C-3 methyl, C3–C4 unsaturated analogue.
Autor:
Fabrizio Alberti, Khairunisa Khairudin, Jonathan A. Davies, Suphattra Sangmalee, Christine L. Willis, Gary D. Foster, Andy M. Bailey
Pleuromutilin is an antibiotic diterpenoid made byClitopilus passeckerianusand related fungi, and it is the progenitor of a growing class of semi-synthetic antibiotics used in veterinary and human medicine. To harness the biotechnological potential o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1d32eabc3fe9ce7c36425e30acaf872
https://doi.org/10.1101/2022.12.03.518960
https://doi.org/10.1101/2022.12.03.518960
Publikováno v:
Natural Products and Bioprospecting
Since the olden times, infectious diseases have largely affected human existence. The newly emerged infections are excessively caused by viruses that are largely associated with mammal reservoirs. The casualties of these emergencies are significantly