Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Fabrizio, Pin"'
Autor:
Rula Atwani, Rohit Pravin Nagare, Amber Rogers, Mayuri Prasad, Virginie Lazar, George Sandusky, Yan Tong, Fabrizio Pin, Salvatore Condello
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-20 (2024)
Abstract Background Platinum-based chemotherapy regimens are a mainstay in the management of ovarian cancer (OC), but emergence of chemoresistance poses a significant clinical challenge. The persistence of ovarian cancer stem cells (OCSCs) at the end
Externí odkaz:
https://doaj.org/article/61ab184379fa418987004cdab1fef9ee
Autor:
Anika Shimonty, Fabrizio Pin, Matthew Prideaux, Gang Peng, Joshua Huot, Hyeonwoo Kim, Clifford J Rosen, Bruce M Spiegelman, Lynda F Bonewald
Publikováno v:
eLife, Vol 12 (2024)
Irisin, released from exercised muscle, has been shown to have beneficial effects on numerous tissues but its effects on bone are unclear. We found significant sex and genotype differences in bone from wildtype (WT) mice compared to mice lacking Fndc
Externí odkaz:
https://doaj.org/article/8d8cec337c354f358d50ad275d1a6a3e
Autor:
Rula Atwani, Rohit Pravin Nagare, Amber Rogers, Mayuri Prasad, Virginie Lazar, George Sandusky, Yan Tong, Fabrizio Pin, Salvatore Condello
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/5c560b7da6f24cf3b90118ef19e01fd7
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 5, Pp 2480-2491 (2022)
Abstract Background Chemotherapy induces a cachectic‐like phenotype, accompanied by skeletal muscle wasting, weakness and mitochondrial dysfunction. Peroxisome proliferator‐activated receptor‐gamma coactivator‐1 alpha (PGC1α), a regulator of
Externí odkaz:
https://doaj.org/article/527c4592d80b4722ad3b7a66e827a803
Autor:
Fabrizio Pin, Marc Beltrà, Lorena Garcia‐Castillo, Barbara Pardini, Giovanni Birolo, Giuseppe Matullo, Fabio Penna, Denis Guttridge, Paola Costelli
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 1, Pp 481-494 (2022)
Abstract Background Cachexia, a syndrome frequently occurring in cancer patients, is characterized by muscle wasting, altered energy and protein metabolism and impaired myogenesis. Tumour‐derived microvesicles (TMVs) containing proteins, messenger
Externí odkaz:
https://doaj.org/article/bae6881d62c64c0fa01a8c15fe09eb44
Autor:
Marc Beltrà, Fabrizio Pin, Domiziana Costamagna, Robin Duelen, Alessandra Renzini, Riccardo Ballarò, Lorena Garcia-Castillo, Ambra Iannuzzi, Viviana Moresi, Dario Coletti, Maurilio Sampaolesi, Fabio Penna, Paola Costelli
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105480- (2022)
Summary: Skeletal muscle repair is accomplished by satellite cells (MuSCs) in cooperation with interstitial stromal cells (ISCs), but the relationship between the function of these cells and the metabolic state of myofibers remains unclear. This stud
Externí odkaz:
https://doaj.org/article/d23a3e4def1d4333a183327d1e23d406
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Cancer cachexia is a debilitating syndrome characterized by skeletal muscle wasting, weakness and fatigue. Several pathogenetic mechanisms can contribute to these muscle derangements. Mitochondrial alterations, altered metabolism and increased oxidat
Externí odkaz:
https://doaj.org/article/7ea3ea982a1043d88734693a732ff4f9
Autor:
Thomas M. O’Connell, Lilian Golzarri-Arroyo, Fabrizio Pin, Rafael Barreto, Stephanie L. Dickinson, Marion E. Couch, Andrea Bonetto
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Background: Cancer cachexia is a severe metabolic disorder characterized by progressive weight loss along with a dramatic loss in skeletal muscle and adipose tissue. Like cancer, cachexia progresses in stages starting with pre-cachexia to cachexia an
Externí odkaz:
https://doaj.org/article/8bc92bbe76294b5b911d317798df2ba7
Autor:
Hyo-Gun Kim, Joshua R. Huot, Fabrizio Pin, Daniel J. Belcher, Andrea Bonetto, Gustavo A. Nader
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 133(6)
We investigated the impact of tumor burden on muscle wasting in metastatic (m) and xenograft (x) models of colorectal cancer (CRC). Male Nod SCID γ and CD2F1 mice were injected subcutaneously or intrasplenically with HCT116 or C26 tumor cells, respe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2523afbc847518311cc867874305dd3
https://pubmed.ncbi.nlm.nih.gov/36201323
https://pubmed.ncbi.nlm.nih.gov/36201323
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 10, Iss 1, Pp 140-154 (2019)
Abstract Background Cancer cachexia is a metabolic disorder involving perturbed energy balance and altered mitochondrial function. Chemotherapy is a primary treatment option for many types of cancer, but there is substantial evidence that some chemot
Externí odkaz:
https://doaj.org/article/db4db5f6b72542b38cf0db3b8f5af6ca