Editorial: The role of glycans in infectious disease, Volume II

Autor: Iván Martínez-Duncker, Héctor M. Mora-Montes, Gerardo R. Vasta, Fabrizio Chiodo

Publikováno v: Frontiers in Microbiology, Vol 13 (2022)

Externí odkaz: https://doaj.org/article/65cada898dbe48baa8eaabbc8f10a57a

Chemical synthesis of glycans up to a 128-mer relevant to the O-antigen of Bacteroides vulgatus

Autor: Qian Zhu, Zhengnan Shen, Fabrizio Chiodo, Simone Nicolardi, Antonio Molinaro, Alba Silipo, Biao Yu

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-7 (2020)

Glycans are abundant biomolecules that mediate essential biological processes, but their chemical synthesis is challenging. Here, the authors report the synthesis of glycans up to a 128-mer, which represents the O-antigen of Bacteroides vulgatus lipo

Externí odkaz: https://doaj.org/article/86bc33511a5442518db1317c3d762cbc

Human Milk Oligosaccharide 2′-Fucosyllactose Inhibits Ligand Binding to C-Type Lectin DC-SIGN but Not to Langerin

Autor: Reshmi Mukherjee, Victor J. Somovilla, Fabrizio Chiodo, Sven Bruijns, Roland J. Pieters, Johan Garssen, Yvette van Kooyk, Aletta D. Kraneveld, Jeroen van Bergenhenegouwen

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 23, p 14745 (2022)

Human milk oligosaccharides (HMOs) and their most abundant component, 2′-Fucosyllactose (2′-FL), are known to be immunomodulatory. Previously, it was shown that HMOs and 2′-FL bind to the C-type lectin receptor DC-SIGN. Here we show, using a li

Externí odkaz: https://doaj.org/article/5e6c25f874b1419e8b6d767dcf6ce385

Simple engineering of hybrid cellulose nanocrystal-gold nanoparticles results in a functional glyconanomaterial with biomolecular recognition properties

Autor: Giacomo Biagiotti, Gianluca Toniolo, Martin Albino, Mirko Severi, Patrizia Andreozzi, Marcello Marelli, Hana Kokot, Giancarlo Tria, Annalisa Guerri, Claudio Sangregorio, Javier Rojo, Debora Berti, Marco Marradi, Stefano Cicchi, Iztok Urbančič, Yvette van Kooyk, Fabrizio Chiodo, Barbara Richichi

Publikováno v: Biagiotti, G, Toniolo, G, Albino, M, Severi, M, Andreozzi, P, Marelli, M, Kokot, H, Tria, G, Guerri, A, Sangregorio, C, Rojo, J, Berti, D, Marradi, M, Cicchi, S, Urbančič, I, van Kooyk, Y, Chiodo, F & Richichi, B 2023, ' Simple engineering of hybrid cellulose nanocrystal-gold nanoparticles results in a functional glyconanomaterial with biomolecular recognition properties ', Nanoscale Horizons, vol. 8, no. 6, pp. 776-782 . https://doi.org/10.1039/d3nh00063j
Nanoscale Horizons, 8(6), 776-782. Royal Society of Chemistry

Cellulose nanocrystal and gold nanoparticles are assembled, in a unique way, to yield a novel modular glyconanomaterial whose surface is then easily engineered with one or two different headgroups, by exploiting a robust click chemistry route. We dem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e7242973a3c5b2db22dca3e415fb224
https://doi.org/10.1039/d3nh00063j

Synthesis and Antibody Binding Studies of Schistosome-Derived Oligo-α-(1-2)-l-Fucosides

Autor: Michael R. Harvey, Fabrizio Chiodo, Wouter Noest, Cornelis H. Hokke, Gijsbert A. van der Marel, Jeroen D.C. Codée

Publikováno v: Molecules, Vol 26, Iss 8, p 2246 (2021)

Schistosomiasis is caused by blood-dwelling parasitic trematodes of the genus Schistosoma and is classified by the WHO as the second most socioeconomically devastating parasitic disease, second only to malaria. Schistosoma expresses a complex array o

Externí odkaz: https://doaj.org/article/c7ce982b28994927a8df42e74158b60e