Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Fabrice Parat"'
Autor:
Fatima-Zahra Benssouina, Fabrice Parat, Claude Villard, Ludovic Leloup, Françoise Garrouste, Jean-marc Sabatier, Lotfi Ferhat, Hervé Kovacic
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4663 (2023)
Noxo1, the organizing element of the Nox1-dependent NADPH oxidase complex responsible for producing reactive oxygen species, has been described to be degraded by the proteasome. We mutated a D-box in Noxo1 to express a protein with limited degradatio
Externí odkaz:
https://doaj.org/article/c8f131fb6d3146d58364959d6f1a49a8
Autor:
Romain Sigaud, Nadège Dussault, Caroline Berenguer-Daizé, Christine Vellutini, Zohra Benyahia, Mylène Cayol, Fabrice Parat, Kamel Mabrouk, Ramiro Vázquez, Maria E. Riveiro, Philippe Metellus, L’Houcine Ouafik
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
VE-cadherin is an essential adhesion molecule in endothelial adherens junctions, and the integrity of these complexes is thought to be regulated by VE-cadherin tyrosine phosphorylation. We have previously shown that adrenomedullin (AM) blockade corre
Externí odkaz:
https://doaj.org/article/213926a4514e458da5ff6110a8a97da0
Autor:
Mathieu Chocry, Ludovic Leloup, Fabrice Parat, Mélissa Messé, Alessandra Pagano, Hervé Kovacic
Publikováno v:
Cancers, Vol 14, Iss 23, p 5894 (2022)
Resistance to treatments is one of the leading causes of cancer therapy failure. Oxaliplatin is a standard chemotherapy used to treat metastatic colorectal cancer. However, its efficacy is greatly reduced by the development of resistances. In a previ
Externí odkaz:
https://doaj.org/article/9db2d8b077964ea7b93f2df0fae68ed0
Autor:
Alessandra Pagano, Gilles Breuzard, Fabrice Parat, Aurélie Tchoghandjian, Dominique Figarella-Branger, Tiphany Coralie De Bessa, Françoise Garrouste, Alexis Douence, Pascale Barbier, Hervé Kovacic
Publikováno v:
Cancers, Vol 13, Iss 22, p 5818 (2021)
The Microtubule-Associated Protein Tau is expressed in several cancers, including low-grade gliomas and glioblastomas. We have previously shown that Tau is crucial for the 2D motility of several glioblastoma cell lines, including U87-MG cells. Using
Externí odkaz:
https://doaj.org/article/d1ee2278df8c4deeb69fd6b8526bc7af
Autor:
Dominique Figarella-Branger, Alessandra Pagano, Aurélie Tchoghandjian, Hervé Kovacic, Alexis Douence, Fabrice Parat, Gilles Breuzard, Françoise Garrouste, Pascale Barbier, Tiphany Coralie De Bessa
Publikováno v:
Cancers
Cancers, 2021, 13 (22), pp.5818. ⟨10.3390/cancers13225818⟩
Volume 13
Issue 22
Cancers, MDPI, 2021, 13 (22), pp.5818. ⟨10.3390/cancers13225818⟩
Cancers, Vol 13, Iss 5818, p 5818 (2021)
Cancers, 2021, 13 (22), pp.5818. ⟨10.3390/cancers13225818⟩
Volume 13
Issue 22
Cancers, MDPI, 2021, 13 (22), pp.5818. ⟨10.3390/cancers13225818⟩
Cancers, Vol 13, Iss 5818, p 5818 (2021)
Simple Summary The Microtubule-associated protein Tau is expressed in different cancers; however, its role and prognostic value are still debated. In the present work, we evaluated the role of Tau in glioblastoma by down-regulating its expression in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2058066cf146a7249746682289d9661e
https://hal-amu.archives-ouvertes.fr/hal-03470226
https://hal-amu.archives-ouvertes.fr/hal-03470226
Autor:
Françoise Garrouste, Mohamed Mousslim, Sylvia Pietri, Vincent Peyrot, Sophie Thétiot-Laurent, Sylvie Thuault, Alessandra Pagano, Jean-Marc Sabatier, Nicolas Andreotti, Marcel Culcasi, Hervé Kovacic, Fabrice Parat, José Luis
Publikováno v:
European Journal of Pharmacology
European Journal of Pharmacology, 2016, ⟨10.1016/j.ejphar.2016.10.011⟩
European Journal of Pharmacology, 2016, ⟨10.1016/j.ejphar.2016.10.011⟩
The NADPH oxidase proteins catalyse the formation of superoxide anion which act as signalling molecules in physiological and pathological processes. Nox1-dependent NADPH oxidase is expressed in heart, lung, colon, blood vessels and brain. Different s
Publikováno v:
Molecular and Cellular Neuroscience. 30:418-428
During neurite elongation, migrating growth cones encounter both permissive and inhibitory substrates, such as laminin and MAG (myelin-associated glycoprotein), respectively. Here, we demonstrated on two neuronal cell lines (PC12 and N1E-115), that l
Autor:
Catherine Bellan, Françoise Garrouste, Maxime Lehmann, Gilbert Pommier, Jacques Marvaldi, Jean-Claude Lissitsky, Frédéric André, Maryse Remacle-Bonnet, Fabrice Parat
Publikováno v:
Endocrinology. 139:3763-3771
To investigate endoproteolytic processing of the type I insulin-like growth factor receptor (IGF-IR), we have examined its structure and activity in the furin-deficient LoVo-C5 cell line. Immunoprecipitation experiments using the monoclonal anti-IGF-
Autor:
Sylvie Monferran, Emilie Faure, Françoise Garrouste, Maxime Lehmann, Fabrice Parat, Hervé Kovacic, Gilbert Pommier, Ludovic Leloup
Publikováno v:
Journal of cell science. 125(Pt 18)
α6β4 integrin is the main component of hemidesmosomes (HD) that stably anchor the epithelium to the underlying basement membrane. Epithelial cell migration requires HD remodelling which can be promoted by epidermal growth factor (EGF). We previousl
Autor:
Julie Milanini, Jean-Claude Hubaud, Fabrice Parat, Jun Takasaki, F Garrouste, Salma Taboubi, Hervé Kovacic, Maxime Lehmann, Gilbert Pommier, Estelle Delamarre
Publikováno v:
FASEB Journal
FASEB Journal, Federation of American Society of Experimental Biology, 2007, 21 (14), pp.4047-4058. ⟨10.1096/fj.06-7476com⟩
FASEB Journal, 2007, 21 (14), pp.4047-4058. ⟨10.1096/fj.06-7476com⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2007, 21 (14), pp.4047-4058. ⟨10.1096/fj.06-7476com⟩
FASEB Journal, 2007, 21 (14), pp.4047-4058. ⟨10.1096/fj.06-7476com⟩
International audience; Reepithelialization is a critical step in wound healing. It is initiated by keratinocyte migration at the wound edges. After wounding, extracellular nucleotides are released by keratinocytes and other skin cells. Here, we repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::340fcda91b2127a1cefc8eecc63898ae
https://hal-amu.archives-ouvertes.fr/hal-01744755
https://hal-amu.archives-ouvertes.fr/hal-01744755