Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Fabrice Lavial"'
Autor:
Sébastien Durand, Marion Bruelle, Fleur Bourdelais, Bigitha Bennychen, Juliana Blin-Gonthier, Caroline Isaac, Aurélia Huyghe, Sylvie Martel, Antoine Seyve, Christophe Vanbelle, Annie Adrait, Yohann Couté, David Meyronet, Frédéric Catez, Jean-Jacques Diaz, Fabrice Lavial, Emiliano P. Ricci, François Ducray, Mathieu Gabut
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Pluripotency is coordinated at multiple levels of gene expression. Here the authors show that ribosome biogenesis is tightly regulated in embryonic stem cells (ESC) to control the translation of transcription and chromatin factors and dictate ESC fat
Externí odkaz:
https://doaj.org/article/a21afed10321427a82d524a32c704e2c
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
During development the embryo must balance lineage specification against the preservation of plasticity using a limited molecular toolkit. In this Perspective, the authors propose Molecular Versatility as a paradigm for grouping molecular mechanisms
Externí odkaz:
https://doaj.org/article/e92b07a4ce784300b334cd242852f5dd
Publikováno v:
The Journal of Poultry Science, Vol 43, Iss 4, Pp 313-322 (2006)
Over the past 3 decades, different strategies were launched to obtain transgenic animals and chicken in particular. Among various technical approaches, the direct modification of the embryo with DNA vectors or viruses is one of the ways of choice whi
Externí odkaz:
https://doaj.org/article/ac86e38243b0450e9f646e01d3242299
Netrin-1 promotes naive pluripotency through Neo1 and Unc5b co-regulation of Wnt and MAPK signalling
Autor:
Alexander Meissner, Manuel Koch, Jenny Y. Zhang, Nicolas Gadot, Xavier Gaume, Fabrice Lavial, Nicolas Rama, Marie Brevet, Pauline Wajda, Thomas Imhof, Bradley J. Merrill, Noémie Combémorel, Jocelyn Charlton, Christina Riemenschneider, Nicolas Allègre, Isabelle Durand, Patrick Mehlen, Claire Chazaud, Pauline Vieugué, Christina Galonska, Duygu Ozmadenci, Giacomo Furlan, Aurélia Huyghe
Publikováno v:
Nature Cell Biology
Nature Cell Biology, 2020, 22 (4), pp.389-400. ⟨10.1038/s41556-020-0483-2⟩
Nature Cell Biology, Nature Publishing Group, 2020, 22 (4), pp.389-400. ⟨10.1038/s41556-020-0483-2⟩
Nature Cell Biology, 2020, 22 (4), pp.389-400. ⟨10.1038/s41556-020-0483-2⟩
Nature Cell Biology, Nature Publishing Group, 2020, 22 (4), pp.389-400. ⟨10.1038/s41556-020-0483-2⟩
International audience; In mouse embryonic stem cells (mESCs), chemical blockade of Gsk3α/β and Mek1/2 (2i) instructs a self-renewing ground state whose endogenous inducers are unknown. Here we show that the axon guidance cue Netrin-1 promotes naiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b770103051f80da7756842265321cc80
https://doi.org/10.1038/s41556-020-0483-2
https://doi.org/10.1038/s41556-020-0483-2
Autor:
Sébastien Durand, Marion Bruelle, Fleur Bourdelais, Bigitha Bennychen, Juliana Blin, Caroline Isaac, Aurélia Huyghe, Antoine Seyve, Christophe Vanbelle, David Meyronet, Frederic CATEZ, Jean-Jacques Diaz, Fabrice Lavial, Emiliano Ricci, François Ducray, Mathieu Gabut
Embryonic stem cell (ESC) fate decisions are regulated by a complex molecular circuitry that requires tight and coordinated gene expression regulations at multiple levels from chromatin organization to mRNA processing. Recently, ribosome biogenesis a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6152e7e7620542043fb7237040aa1f08
https://doi.org/10.21203/rs.3.rs-738081/v1
https://doi.org/10.21203/rs.3.rs-738081/v1
Autor:
Nicolas Gadot, A. Huyghe, J. Stüder, Peter Mulligan, Jose M. Polo, L. De Matteo, Hinrich Gronemeyer, Fabrice Lavial, Nicolas Rama, Marie Brevet, R. Dante, Juexuan Wang, Marco Antonio Mendoza-Parra, Yong Yu, P. Wajda, Jan Schroeder, Pentao Liu, Benjamin Gibert, I. Goddard, F. Mugnier, G. Furlan, Maha Siouda
Coordinated changes of cellular identity and plasticity are critical for pluripotent reprogramming (PR) and malignant transformation (MT). However, the molecular circuitries orchestrating these modifications, as well as their degree of analogy during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6df432a02d950c412fa47251508e1b9
https://doi.org/10.1101/2020.12.28.424606
https://doi.org/10.1101/2020.12.28.424606
Publikováno v:
Cancer Cell. 33:164-172
Completion of early stages of tumorigenesis relies on the dynamic interplay between the initiating oncogenic event and the cellular context. Here, we review recent findings indicating that each differentiation stage within a defined cellular lineage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e14f93ecd5b6e72a4b285f310385bf9
https://doi.org/10.1016/j.ccell.2018.01.007
https://doi.org/10.1016/j.ccell.2018.01.007
Autor:
Patrick Mehlen, Fabrice Lavial
Publikováno v:
médecine/sciences. 32:241-244
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99257289b75e1eef6948f0d6723d8aa3
https://doi.org/10.1051/medsci/20163203005
https://doi.org/10.1051/medsci/20163203005
Autor:
Gabriel Ichim, Géraldine Gouysse, Jean-Yves Scoazec, Marie-May Coissieux, Anne-Laure Genevois, Loraine Jarrosson-Wuilleme, Fabrice Lavial, David Goldschneider, Servane Tauszig-Delamasure, Florian Lepinasse, Zdenko Herceg, Marie-Pierre Lambert, Patrick Mehlen
Publikováno v:
Proceedings of the National Academy of Sciences. 110:3017-3022
The TrkC neurotrophin receptor belongs to the functional dependence receptor family, members of which share the ability to induce apoptosis in the absence of their ligands. Such a trait has been hypothesized to confer tumor-suppressor activity. Indee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9099c722c77573ea20c15e0c91f1302a
https://doi.org/10.1073/pnas.1212333110
https://doi.org/10.1073/pnas.1212333110
Autor:
Michiel Vermeulen, Thomas L. Carroll, Gordon Peters, Ana O'Loghlen, Tomas Racek, Ana M. Muñoz-Cabello, Fabrice Lavial, Emily Bernstein, Véronique Azuara, Ambrosius P. Snijders, Natalia Kunowska, Alexandre Gaspar-Maia, Helen Pemberton, Johannes Graumann, Ana Banito, Jesús Gil, Niall Dillon, Patrizia Beolchi, Hsan-au Wu, Edith Heard, Osamu Masui
Publikováno v:
Cell Stem Cell
Summary The Polycomb Group (PcG) of chromatin modifiers regulates pluripotency and differentiation. Mammalian genomes encode multiple homologs of the Polycomb repressive complex 1 (PRC1) components, including five orthologs of the Drosophila Polycomb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6280199c427237086eb25547426719ff
http://europepmc.org/articles/PMC3277884
http://europepmc.org/articles/PMC3277884