Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Fabrice Godfroid"'
Autor:
Leen Moens, Philippe Hermand, Tine Wellens, Greet Wuyts, Rita Derua, Etienne Waelkens, Carine Ysebaert, Fabrice Godfroid, Xavier Bossuyt
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 14, Iss 5, Pp 1234-1242 (2018)
Serotype-independent protein-based pneumococcal vaccines represent attractive alternatives to capsular polysaccharide-based vaccines. The aim of this study was to identify novel immunogenic proteins from Streptococcus pneumoniae that may be used in p
Externí odkaz:
https://doaj.org/article/a6bf979410f44518a70c0d6901b5d5e6
Autor:
Philippe Hermand, Annick Vandercammen, Emmanuel Mertens, Emmanuel Di Paolo, Vincent Verlant, Philippe Denoël, Fabrice Godfroid
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 13, Iss 1, Pp 220-228 (2017)
The use of protein antigens able to protect against the majority of Streptococcus pneumoniae serotypes is envisaged as stand-alone and/or complement to the current capsular polysaccharide-based pneumococcal vaccines. Pneumolysin (Ply) is a key virule
Externí odkaz:
https://doaj.org/article/8b0e32c5221346c79227f1a345cbe296
Autor:
Philippe Hermand, Annick Vandercammen, Fabrice Godfroid, Emmanuel Mertens, Vincent Verlant, Philippe Denoel, Emmanuel Di Paolo
Publikováno v:
Human Vaccines & Immunotherapeutics
The use of protein antigens able to protect against the majority of Streptococcus pneumoniae serotypes is envisaged as stand-alone and/or complement to the current capsular polysaccharide-based pneumococcal vaccines. Pneumolysin (Ply) is a key virule
Autor:
Vincent Weynants, Carine Ysebaert, Laura A. Novotny, Philippe Hermand, Lauren O. Bakaletz, Philippe Denoel, Fabrice Godfroid
Publikováno v:
Infection and Immunity
PE-PilA is a fusion protein composed of immunologically relevant parts of protein E (PE) and the majority subunit of the type IV pilus (PilA), two major antigens of nontypeable Haemophilus influenzae (NTHi). Here we report on the preclinical evaluati
Autor:
Philippe Hermand, Leen Moens, Fabrice Godfroid, Greet Wuyts, Etienne Waelkens, Tine Wellens, Carine Ysebaert, Rita Derua, Xavier Bossuyt
Publikováno v:
Human vaccinesimmunotherapeutics. 14(5)
Serotype-independent protein-based pneumococcal vaccines represent attractive alternatives to capsular polysaccharide-based vaccines. The aim of this study was to identify novel immunogenic proteins from Streptococcus pneumoniae that may be used in p
Autor:
Laura A. Novotny, Joseph A. Jurcisek, Fabrice Godfroid, Lauren O. Bakaletz, Philippe Denoël, Jan Poolman
Publikováno v:
Vaccine. 24:4804-4811
Passive transfer of a pediatric human serum pool generated against polysaccharide-protein D conjugate vaccines conferred approximately 34% protection against development of ascending NTHI-induced OM when used in a chinchilla viral-bacterial co-infect
Publikováno v:
Vaccine. 23:5333-5341
A significant increase in the incidence of pertussis in adolescents and adults has been observed in vaccinated populations. Concomitantly, emergence of novel pertussis toxin and pertactin types in circulating Bordetella pertussis isolates was noticed
Publikováno v:
Expert Review of Vaccines. 4:757-778
Whooping cough remains an endemic disease, and the re-emergence of pertussis in older children and adolescents has been reported in several countries, despite high vaccine coverage. Polymorphism of Bordetella pertussis has been observed over time, an
Autor:
Kirsi Sepponen, Anna Kallio, Philippe Denoël, Merit Melin, Fabrice Godfroid, Philippe Hermand
Publikováno v:
Infection and immunity. 82(4)
Pneumococcal adherence to mucosal surfaces is a critical step in nasopharyngeal colonization, but so far few pneumococcal adhesins involved in the interaction with host cells have been identified. PhtA, PhtB, PhtD, and PhtE are conserved pneumococcal
Autor:
Fabrice Godfroid, Vincent Weynants, Anne Tibor, Thierry Laurent, Xavier De Bolle, Pascal Mertens, Jean-Jacques Letesson
Publikováno v:
Journal of Molecular Biology. 294:181-191
The lipopolysaccharide (LPS) is up to now the only identified major virulence determinant of Brucella. This bacterium is responsible for brucellosis in animals and for Malta fever in humans. Several monoclonal antibodies (mAbs) directed against vario