Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Fabrice Darbellay"'
Autor:
Fabrice Darbellay, Anna Ramisch, Lucille Lopez-Delisle, Michael Kosicki, Antonella Rauseo, Zahra Jouini, Axel Visel, Guillaume Andrey
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Chondrocyte differentiation controls skeleton development and stature. Here we provide a comprehensive map of chondrocyte-specific enhancers and show that they provide a mechanistic framework through which non-coding genetic variants can inf
Externí odkaz:
https://doaj.org/article/b064cf129fd146118f68faab2889d660
Autor:
Sudha Sunil Rajderkar, Kitt Paraiso, Maria Luisa Amaral, Michael Kosicki, Laura E. Cook, Fabrice Darbellay, Cailyn H. Spurrell, Marco Osterwalder, Yiwen Zhu, Han Wu, Sarah Yasmeen Afzal, Matthew J. Blow, Guy Kelman, Iros Barozzi, Yoko Fukuda-Yuzawa, Jennifer A. Akiyama, Veena Afzal, Stella Tran, Ingrid Plajzer-Frick, Catherine S. Novak, Momoe Kato, Riana D. Hunter, Kianna von Maydell, Allen Wang, Lin Lin, Sebastian Preissl, Steven Lisgo, Bing Ren, Diane E. Dickel, Len A. Pennacchio, Axel Visel
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract The genetic basis of human facial variation and craniofacial birth defects remains poorly understood. Distant-acting transcriptional enhancers control the fine-tuned spatiotemporal expression of genes during critical stages of craniofacial d
Externí odkaz:
https://doaj.org/article/ad066eccb027472d812a541544ff79a2
Autor:
Pierluigi G. Manti, Fabrice Darbellay, Marion Leleu, Aisling Y. Coughlan, Bernard Moret, Julien Cuennet, Frederic Droux, Magali Stoudmann, Gian-Filippo Mancini, Agnès Hautier, Jessica Sordet-Dessimoz, Stephane D. Vincent, Giuseppe Testa, Giulio Cossu, Yann Barrandon
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2647 (2022)
Prdm1 mutant mice are one of the rare mutant strains that do not develop whisker hair follicles while still displaying a pelage. Here, we show that Prdm1 is expressed at the earliest stage of whisker development in clusters of mesenchymal cells befor
Externí odkaz:
https://doaj.org/article/ef69336a211c495e8787c9a0430add85
Autor:
Huan Liu, Kaylia Duncan, Annika Helverson, Priyanka Kumari, Camille Mumm, Yao Xiao, Jenna Colavincenzo Carlson, Fabrice Darbellay, Axel Visel, Elizabeth Leslie, Patrick Breheny, Albert J Erives, Robert A Cornell
Publikováno v:
eLife, Vol 9 (2020)
Genome-wide association studies for non-syndromic orofacial clefting (OFC) have identified single nucleotide polymorphisms (SNPs) at loci where the presumed risk-relevant gene is expressed in oral periderm. The functional subsets of such SNPs are dif
Externí odkaz:
https://doaj.org/article/54a09bab8c194db6a5efec438255ab05
Autor:
Patrick Schorderet, Nicolas Lonfat, Fabrice Darbellay, Patrick Tschopp, Sandra Gitto, Natalia Soshnikova, Denis Duboule
Publikováno v:
PLoS Genetics, Vol 9, Iss 11, p e1003951 (2013)
Polycomb group (PcG) proteins are essential for the repression of key factors during early development. In Drosophila, the polycomb repressive complexes (PRC) associate with defined polycomb response DNA elements (PREs). In mammals, however, the mech
Externí odkaz:
https://doaj.org/article/a8e696c108024ddba0a0a499796e247a
Autor:
Fabrice Darbellay, Anna Ramisch, Lucille Lopez-Delisle, Michael Kosicki, Axel Visel, Guillaume Andrey
The precisely orchestrated differentiation of chondrocytes during skeleton development is a critical determinant of human height and body shape and disruptions of this process can cause severe skeletal abnormalities. The ultimate size and shape of ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::631f3e83aaf2238a753f98dd367e31b2
https://doi.org/10.1101/2023.05.10.539849
https://doi.org/10.1101/2023.05.10.539849
Autor:
Ferdinand Marlétaz, Elisa de la Calle-Mustienes, Rafael D. Acemel, Christina Paliou, Silvia Naranjo, Pedro Manuel Martínez-García, Ildefonso Cases, Victoria A. Sleight, Christine Hirschberger, Marina Marcet-Houben, Dina Navon, Ali Andrescavage, Ksenia Skvortsova, Paul Edward Duckett, Álvaro González-Rajal, Ozren Bogdanovic, Johan H. Gibcus, Liyan Yang, Lourdes Gallardo-Fuentes, Ismael Sospedra, Javier Lopez-Rios, Fabrice Darbellay, Axel Visel, Job Dekker, Neil Shubin, Toni Gabaldón, Tetsuya Nakamura, Juan J. Tena, Darío G. Lupiáñez, Daniel S. Rokhsar, José Luis Gómez-Skarmeta
Skates are cartilaginous fish whose body plan features enlarged wing-like pectoral fins, enabling them to thrive in benthic environments1,2. However, the molecular underpinnings of this unique trait remain unclear. Here we investigate the origin of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89f1bfcf673c5cdf0b7b2bf7b8f2b39d
http://edoc.mdc-berlin.de/23267/2/23267suppl.zip
http://edoc.mdc-berlin.de/23267/2/23267suppl.zip
Autor:
Pierluigi G, Manti, Fabrice, Darbellay, Marion, Leleu, Aisling Y, Coughlan, Bernard, Moret, Julien, Cuennet, Frederic, Droux, Magali, Stoudmann, Gian-Filippo, Mancini, Agnès, Hautier, Jessica, Sordet-Dessimoz, Stephane D, Vincent, Giuseppe, Testa, Giulio, Cossu, Yann, Barrandon
Publikováno v:
Biomedicines. 10(10)
Autor:
Ferdinand Marletaz, Elisa de la Calle-Mustienes, Rafael D. Acemel, Tetsuya Nakamura, Christina Paliou, Silvia Naranjo, Pedro M. Martinez-Garcia, Ildefonso Cases, Victoria A. Sleight, Christine Hirschberger, Marina Marcet-Houben, Dina Navon, Ali Andrescavage, Ksenia Skvortsova, Paul E. Duckett, Alvaro Gonzalez-Rajal, Ozren Bogdanovic, Johan H. Gibcus, Liyan Yang, Lourdes Gallardo-Fuentes, Ismael Sospedra, Javier Lopez-Rios, Fabrice Darbellay, Axel Visel, Job Dekker, Neil Shubin, Toni Gabaldon, Juan J. Tena, Dario G. Lupianez, Daniel S. Rokhsar, Jose L. Gomez-Skarmeta
Skates are cartilaginous fish whose novel body plan features remarkably enlarged wing-like pectoral fins that allow them to thrive in benthic environments. The molecular underpinnings of this unique trait, however, remain elusive. Here we investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dda8760af2b27d9c2553990373d64909
https://doi.org/10.1101/2022.03.21.485123
https://doi.org/10.1101/2022.03.21.485123
Autor:
Priyanka Kumari, Axel Visel, Ryan Z. Friedman, Fabrice Darbellay, Barak A. Cohen, Lira Pi, Robert A. Cornell, Elizabeth J. Leslie, Annika Helverson, Sarah W. Curtis, Michael A. White
Publikováno v:
The FASEB Journal. 35